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GDF1 elisa kit :: Human GDF1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2501702
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GDF1, ELISA Kit

★Popular Item★
 Also Known As   

Human GDF1 (Growth Differentiation Factor 1) ELISA Kit

 Product Gene Name   

GDF1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    187500
 3D Structure    ModBase 3D Structure for P27539
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human GDF1. No significant cross-reactivity or interference between Human GDF1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human GDF1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    31.25-2000pg/mL
 Sensitivity    Min: 18.75pg/mL; Max: 2000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GDF1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GDF1 purchase    MBS2501702 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GDF1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25-2000pg/mL in biological research samples containing GDF1, with an estimated sensitivity of Min: 18.75pg/mL; Max: 2000pg/mL. The ELISA analytical biochemical technique of the MBS2501702 kit is based on GDF1 antibody-GDF1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GDF1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GDF1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for GDF1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of GDF1 in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human GDF1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human GDF1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human GDF1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human GDF1. You can calculate the concentration of Human GDF1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of GDF1 elisa kit    GDF1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2501702. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GDF1. It may not necessarily be applicable to this product.
 NCBI GI #    18490663
 NCBI GeneID    2657
 NCBI Accession #    AAH22450.1 [Other Products]
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 UniProt Primary Accession #    P27539 [Other Products]
 UniProt Secondary Accession #    O43344 [Other Products]
 UniProt Related Accession #    P27539 [Other Products]
 Molecular Weight    39,475 Da
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 NCBI Official Full Name    GDF1 protein
 NCBI Official Synonym Full Names    growth differentiation factor 1
 NCBI Official Symbol    GDF1 [Similar Products]
 NCBI Official Synonym Symbols   
RAI; DORV; DTGA3
[Similar Products]
 NCBI Protein Information    embryonic growth/differentiation factor 1; GDF-1
 UniProt Protein Name    Embryonic growth/differentiation factor 1
 Protein Family    Embryonic growth/differentiation factor
 UniProt Gene Name    GDF1 [Similar Products]
 UniProt Synonym Gene Names    GDF-1 [Similar Products]
 UniProt Entry Name    GDF1_HUMAN
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 NCBI Summary for GDF1    This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Mar 2014]
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 UniProt Comments for GDF1    GDF1: May mediate cell differentiation events during embryonic development. Defects in GDF1 are a cause of conotruncal heart malformations (CTHM). A group of congenital heart defects involving the outflow tracts. Examples include truncus arteriosus communis, double-outlet right ventricle and transposition of great arteries. Truncus arteriosus communis is characterized by a single outflow tract instead of a separate aorta and pulmonary artery. In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. In double outlet of the right ventricle, both the pulmonary artery and aorta arise from the right ventricle. Defects in GDF1 are the cause of transposition of the great arteries dextro-looped type 3 (DTGA3). A congenital heart defect consisting of complete inversion of the great vessels, so that the aorta incorrectly arises from the right ventricle and the pulmonary artery incorrectly arises from the left ventricle. This creates completely separate pulmonary and systemic circulatory systems, an arrangement that is incompatible with life. The presence or absence of associated cardiac anomalies defines the clinical presentation and surgical management of patients with transposition of the great arteries. Defects in GDF1 are a cause of tetralogy of Fallot (TOF). A congenital heart anomaly which consists of pulmonary stenosis, ventricular septal defect, dextroposition of the aorta (aorta is on the right side instead of the left) and hypertrophy of the right ventricle. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing cyanosis. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p12

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; regulation of apoptosis; regulation of MAPKKK cascade; cell development; growth

Disease: Transposition Of The Great Arteries, Dextro-looped 3; Right Atrial Isomerism; Conotruncal Heart Malformations; Tetralogy Of Fallot
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 Research Articles on GDF1    1. This implies that Gdf1 potentiates Nodal activity by stabilizing a low molecular weight fraction that is susceptible to neutralization by soluble Acvr2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GDF1 elisa kitPathways associated with GDF1 elisa kit
 Reference Product  PubMed Publications
 CFC1 elisa kit  >6 publications with GDF1 and CFC1
 FOXH1 elisa kit  >3 publications with GDF1 and FOXH1
 SMAD2 elisa kit  >3 publications with GDF1 and SMAD2
 IHH elisa kit  >2 publications with GDF1 and IHH
 ACVR1C elisa kit  >1 publications with GDF1 and ACVR1C
 LASS1 elisa kit  >1 publications with GDF1 and LASS1
 MED13L elisa kit  >1 publications with GDF1 and MED13L
 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Signaling By NODAL Pathway antibodies  Signaling By NODAL Pathway Diagram
 Sphingolipid De Novo Biosynthesis Pathway antibodies  Sphingolipid De Novo Biosynthesis Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
Diseases associated with GDF1 elisa kitOrgans/Tissues associated with GDF1 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >8 publications with GDF1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >8 publications with GDF1 and Heart Diseases
 Transposition of Great Vessels Antibodies  >3 publications with GDF1 and Transposition of Great Vessels
 Genital Diseases, Male Antibodies  >2 publications with GDF1 and Genital Diseases, Male
 Prostatic Diseases Antibodies  >2 publications with GDF1 and Prostatic Diseases
 Tetralogy of Fallot Antibodies  >2 publications with GDF1 and Tetralogy of Fallot
 Hypertrophy Antibodies  >1 publications with GDF1 and Hypertrophy
 Edema Antibodies  >1 publications with GDF1 and Edema
 Double Outlet Right Ventricle Antibodies  >1 publications with GDF1 and Double Outlet Right Ventricle
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >8 publications with GDF1 and Nerve
 Embryonic Tissue Antibodies  >7 publications with GDF1 and Embryonic Tissue
 Brain Antibodies  >6 publications with GDF1 and Brain
 Muscle Antibodies  >5 publications with GDF1 and Muscle
 Lung Antibodies  >2 publications with GDF1 and Lung
 Testis Antibodies  >1 publications with GDF1 and Testis
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