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GLP-2 elisa kit :: Human GLP-2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2510411
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GLP-2, ELISA Kit

★Popular Item★
 Also Known As   

Human GLP-2 (Glucagon Like Peptide 2) ELISA Kit

 Product Gene Name   

GLP-2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2510411 COA    COA PDF
 OMIM    603659
 3D Structure    ModBase 3D Structure for O95838
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and some recombinant Human GLP-2. No significant crossreactivity or interference between Human GLP-2 and analogues was observed.
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 Samples    serum, plasma and other biological fluids
 Detection Range    0.16-10 ng/mL
 Sensitivity    0.10 ng/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Human GLP-2 were tested 20 times on one plate, respectively.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Human GLP-2 were tested on 3 different plates, 20 replicates in each plate.
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GLP-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GLP-2 purchase    MBS2510411 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GLP-2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.16-10 ng/mL in biological research samples containing GLP-2, with an estimated sensitivity of 0.10 ng/mL. The ELISA analytical biochemical technique of the MBS2510411 kit is based on GLP-2 antibody-GLP-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GLP-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GLP-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). Human GLP-2 (Glucagon Like Peptide 2) ELISA Kit

In humans glucagon-like peptide-2 (GLP-2) is a 33 amino acid peptide. GLP-2 is created by specific post-translational proteolytic cleavage of glucagon in a process that also liberates the related glucagon-like peptide-1 (GLP-1).
GLP-2 is produced by the intestinal endocrine L cell and by various neurons in the central nervous system. Intestinal GLP-2 is co-secreted along with GLP-1 upon nutrient ingestion. Glucagon is a peptide hormone, produced by alpha cells of the pancreas that raises the concentration of glucose in the bloodstream. Its effect is opposite that of insulin, which lowers the glucose concentration. Thus, it is part of a feedback system that keeps blood glucose levels at a stable level.
GLP-2 results in a number of biological actions in humans and rodents, these include intestinal growth, enhancement of intestinal function, reduction in bone breakdown and neuroprotection. Some research suggests that GLP-2 and related analogs may be treatments for short bowel syndrome, Crohn's disease, osteoporosis and as adjuvant therapy during cancer chemotherapy.

The concentration of glucagon peptide 2 in the test sample (plasma, blood) can be derived from a standard curve. The details of assay and reagents in this ELISA kit can be found in the product datasheet. Cross species reactivity has been demonstrated to mouse, rat and human sequences.
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Related Product Information for GLP-2 elisa kit

   Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Human GLP-2 concentrations in serum, plasma and other biological fluids.
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 Typical Testing Data/Standard Curve (for reference only) of GLP-2 elisa kit    GLP-2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2510411. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GLP-2. It may not necessarily be applicable to this product.
 NCBI GI #    4758438
 NCBI GeneID    9340
 NCBI Accession #    NP_004237.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004246.2 [Other Products]
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 UniProt Primary Accession #    O95838 [Other Products]
 UniProt Secondary Accession #    Q4VAT3 [Other Products]
 UniProt Related Accession #    O95838 [Other Products]
 Molecular Weight    63,001 Da
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 NCBI Official Full Name    glucagon-like peptide 2 receptor
 NCBI Official Synonym Full Names    glucagon-like peptide 2 receptor
 NCBI Official Symbol    GLP2R [Similar Products]
 NCBI Protein Information    glucagon-like peptide 2 receptor; GLP-2 receptor
 UniProt Protein Name    Glucagon-like peptide 2 receptor
 UniProt Gene Name    GLP2R [Similar Products]
 UniProt Synonym Gene Names    GLP-2 receptor; GLP-2-R; GLP-2R [Similar Products]
 UniProt Entry Name    GLP2R_HUMAN
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 NCBI Summary for GLP-2    This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]
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 UniProt Comments for GLP-2    GLP2R: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; glucagon receptor activity

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; positive regulation of cell proliferation
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 Research Articles on GLP-2    1. Report gastrointestinal GLP-2 receptor and limited utility of GLP-2 in the management of inflammatory intestinal disorders.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GLP-2 elisa kitPathways associated with GLP-2 elisa kit
 Reference Product  PubMed Publications
 GCG elisa kit  >4 publications with GLP-2 and GCG
 GCGR elisa kit  >2 publications with GLP-2 and GCGR
 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Organs/Tissues associated with GLP-2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >10 publications with GLP-2 and Intestine
 Brain Antibodies  >3 publications with GLP-2 and Brain
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