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GKRP elisa kit :: Human Glucokinase Regulatory Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS039471 GKRP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glucokinase Regulatory Protein (GKRP), ELISA Kit

 Also Known As   

Human Glucokinase Regulatory Protein ELISA Kit

 Product Gene Name   

GKRP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 2; NC_000002.11 (27719706..27746551). Location: 2p23
 OMIM    600842
 3D Structure    ModBase 3D Structure for Q14397
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 Species Reactivity    Human
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of GKRP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GKRP purchase    MBS039471 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glucokinase Regulatory Protein (GKRP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GKRP. The ELISA analytical biochemical technique of the MBS039471 kit is based on GKRP antibody-GKRP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GKRP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GKRP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GKRP. It may not necessarily be applicable to this product.
 NCBI GI #    221625433
 NCBI GeneID    2646
 NCBI Accession #    NP_001477.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001486.3 [Other Products]
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 UniProt Primary Accession #    Q14397 [Other Products]
 UniProt Secondary Accession #    Q53RY6; Q99522; A1L4C2 [Other Products]
 UniProt Related Accession #    Q14397 [Other Products]
 Molecular Weight    68,685 Da
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 NCBI Official Full Name    glucokinase regulatory protein
 NCBI Official Synonym Full Names    glucokinase (hexokinase 4) regulator
 NCBI Official Symbol    GCKR [Similar Products]
 NCBI Official Synonym Symbols   
GKRP; FGQTL5
[Similar Products]
 NCBI Protein Information    glucokinase regulatory protein
 UniProt Protein Name    Glucokinase regulatory protein
 Protein Family    Glucokinase regulatory protein
 UniProt Gene Name    GCKR [Similar Products]
 UniProt Synonym Gene Names    Glucokinase regulator [Similar Products]
 UniProt Entry Name    GCKR_HUMAN
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 NCBI Summary for GKRP    This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]
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 UniProt Comments for GKRP    GCKR: a key regulator of glucokinase in the liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen. When expressed alone, both glucokinase and GCKR localize predominantly to the cytoplasm. Co-expression induces both proteins to localize in the nucleus.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 2p23

Cellular Component: nucleoplasm; mitochondrion; cytoplasm; cytosol

Molecular Function: enzyme inhibitor activity; protein domain specific binding; protein binding; enzyme binding; carbohydrate binding

Biological Process: negative regulation of glucokinase activity; urate metabolic process; protein import into nucleus, translocation; hexose transport; carbohydrate metabolic process; cell glucose homeostasis; pathogenesis; glucose transport; transmembrane transport; response to fructose stimulus; positive regulation of glucokinase activity

Disease: Fasting Plasma Glucose Level Quantitative Trait Locus 5
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 Research Articles on GKRP    1. Triglycerides-increasing alleles of GCKR variants reduce insulin and HOMA-IR index, and protect from insulin resistance in Chinese children.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GKRP elisa kitPathways associated with GKRP elisa kit
 Reference Product  PubMed Publications
 GCK elisa kit  >36 publications with GKRP and GCK
 APOA5 elisa kit  >22 publications with GKRP and APOA5
 MTNR1B elisa kit  >15 publications with GKRP and MTNR1B
 SLC2A2 elisa kit  >5 publications with GKRP and SLC2A2
 TRAF2 elisa kit  >4 publications with GKRP and TRAF2
 KHK elisa kit  >2 publications with GKRP and KHK
 HK1 elisa kit  >1 publications with GKRP and HK1
 Products by Pathway  Pathway Diagram
 Glucose Transport Pathway antibodies  Glucose Transport Pathway Diagram
 Hexose Transport Pathway antibodies  Hexose Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Regulation Of Glucokinase By Glucokinase Regulatory Protein Pathway antibodies  Regulation Of Glucokinase By Glucokinase Regulatory Protein Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with GKRP elisa kitOrgans/Tissues associated with GKRP elisa kit
 Disease Name  Pubmed Publications
 Diabetes Mellitus, Type 2 Antibodies  >49 publications with GKRP and Diabetes Mellitus, Type 2
 Insulin Resistance Antibodies  >27 publications with GKRP and Insulin Resistance
 Cardiovascular Diseases Antibodies  >25 publications with GKRP and Cardiovascular Diseases
 Hyperglycemia Antibodies  >18 publications with GKRP and Hyperglycemia
 Dyslipidemias Antibodies  >16 publications with GKRP and Dyslipidemias
 Fatty Liver Antibodies  >15 publications with GKRP and Fatty Liver
 Liver Diseases Antibodies  >14 publications with GKRP and Liver Diseases
 Heart Diseases Antibodies  >13 publications with GKRP and Heart Diseases
 Hypertriglyceridemia Antibodies  >13 publications with GKRP and Hypertriglyceridemia
 Hyperlipidemias Antibodies  >12 publications with GKRP and Hyperlipidemias
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >62 publications with GKRP and Liver
 Vascular Antibodies  >5 publications with GKRP and Vascular
 Muscle Antibodies  >5 publications with GKRP and Muscle
 Lung Antibodies  >2 publications with GKRP and Lung
 Testis Antibodies  >1 publications with GKRP and Testis
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