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GRP94 elisa kit :: Human Glucose Regulated Protein 94 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS019841 GRP94 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glucose Regulated Protein 94 (GRP94), ELISA Kit

 Also Known As   

Human Glucose Regulated Protein 94 ELISA Kit

 Product Gene Name   

GRP94 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 15; NC_006597.3 (42456790..42474117). Location: chromosome: 15
 3D Structure    ModBase 3D Structure for P41148
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 Species Reactivity    Human
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GRP94 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GRP94 purchase    MBS019841 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glucose Regulated Protein 94 (GRP94) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRP94. The ELISA analytical biochemical technique of the MBS019841 kit is based on GRP94 antibody-GRP94 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRP94 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRP94. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GRP94. It may not necessarily be applicable to this product.
 NCBI GI #    403497
 NCBI GeneID    404019
 NCBI Accession #    AAA17708.1 [Other Products]
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 UniProt Primary Accession #    P41148 [Other Products]
 UniProt Related Accession #    P41148 [Other Products]
 Molecular Weight    92,514 Da
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 NCBI Official Full Name    GRP94
 NCBI Official Symbol    HSP90B1 [Similar Products]
 NCBI Official Synonym Symbols   
TRA1; GRP94
[Similar Products]
 NCBI Protein Information    endoplasmin; GRP-94; tumor rejection antigen 1; 94 kDa glucose-regulated protein; tumor rejection antigen (gp96) 1; heat shock protein 90 kDa beta member 1
 UniProt Protein Name    Endoplasmin
 UniProt Synonym Protein Names   
94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1
 UniProt Gene Name    HSP90B1 [Similar Products]
 UniProt Synonym Gene Names    GRP94; TRA1; GRP-94 [Similar Products]
 UniProt Entry Name    ENPL_CANFA
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 UniProt Comments for GRP94    GRP94: Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. Homodimer; disulfide-linked. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with AIMP1; regulates its retention in the endoplasmic reticulum. Interacts with OS9. Interacts with CNPY3. This interaction is disrupted in the presence of ATP. Interacts with TLR4 and TLR9, but not with TLR3. Belongs to the heat shock protein 90 family.

Protein type: Heat shock protein; Apoptosis; Secreted; Secreted, signal peptide

Cellular Component: extracellular matrix; endoplasmic reticulum membrane; focal adhesion; sarcoplasmic reticulum; perinuclear region of cytoplasm; endoplasmic reticulum lumen; melanosome; plasma membrane; midbody; cytosol; nucleus

Molecular Function: low-density lipoprotein receptor binding; RNA binding; unfolded protein binding; virion binding; protein phosphatase binding; ATP binding

Biological Process: actin rod formation; ER-associated protein catabolic process; protein folding; response to hypoxia; regulation of phosphoprotein phosphatase activity; negative regulation of apoptosis
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 Research Articles on GRP94    1. The ATPase activity of GRP94 is essential for chaperone activity in vivo and the essential protein-binding domain of GRP94 is distinct from the N-terminal domain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GRP94 elisa kitPathways associated with GRP94 elisa kit
 Reference Product  PubMed Publications
 HSPD1 elisa kit  >3 publications with GRP94 and HSPD1
 TLR9 elisa kit  >2 publications with GRP94 and TLR9
 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By ATF6-alpha Pathway antibodies  Activation Of Chaperone Genes By ATF6-alpha Pathway Diagram
 Activation Of Chaperones By ATF6-alpha Pathway antibodies  Activation Of Chaperones By ATF6-alpha Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
Diseases associated with GRP94 elisa kitOrgans/Tissues associated with GRP94 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with GRP94 and Neoplasms
 Disease Models, Animal Antibodies  >3 publications with GRP94 and Disease Models, Animal
 Nervous System Diseases Antibodies  >2 publications with GRP94 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with GRP94 and Brain Diseases
 Testicular Diseases Antibodies  >1 publications with GRP94 and Testicular Diseases
 Breast Neoplasms Antibodies  >1 publications with GRP94 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with GRP94 and Cardiovascular Diseases
 Drug Toxicity Antibodies  >1 publications with GRP94 and Drug Toxicity
 Infertility, Male Antibodies  >1 publications with GRP94 and Infertility, Male
 Inflammation Antibodies  >1 publications with GRP94 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with GRP94 and Brain
 Testis Antibodies  >2 publications with GRP94 and Testis
 Thyroid Antibodies  >1 publications with GRP94 and Thyroid
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