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SLC2A4 elisa kit :: Human Glucose transporter 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS283942 SLC2A4 elisa kit
Unit / Price
48-Strip-Wells  /  $465 +1 FREE 8GB USB
96-Strip-Wells  /  $790 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,500 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,655 +8 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glucose transporter 4 (SLC2A4), ELISA Kit

★Popular Item★
 Also Known As   

Human Glucose transporter 4 (GLUT4) ELISA Kit

 Product Synonym Names    GLUT4; glucose transporter 4|insulin-responsive glucose transporter type 4
 Product Gene Name   

SLC2A4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    M20747 mRNA
 3D Structure    ModBase 3D Structure for P14672
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human SLC2A4. No significant cross-reactivity or interference between Human SLC2A4 and analogues was observed.
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 Samples    Serum, Plasma, Other biological fluids
 Assay Type    Sandwich
 Sample Volume    1-200 uL
 Precision    Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
 Detection Wavelength    450 nm
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 Preparation and Storage    Store at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SLC2A4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLC2A4 purchase    MBS283942 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glucose transporter 4 (SLC2A4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC2A4. The ELISA analytical biochemical technique of the MBS283942 kit is based on SLC2A4 antibody-SLC2A4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC2A4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC2A4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SLC2A4 elisa kit

   Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate SLC2A4 in samples. An antibody specific for SLC2A4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySLC2A4 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SLC2A4 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SLC2A4 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS283942. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SLC2A4. It may not necessarily be applicable to this product.
 NCBI GI #    4507011
 NCBI GeneID    6517
 NCBI Accession #    NP_001033.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042.2 [Other Products]
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 UniProt Primary Accession #    P14672 [Other Products]
 UniProt Secondary Accession #    Q05BQ3; Q14CX2 [Other Products]
 UniProt Related Accession #    P14672 [Other Products]
 Molecular Weight    43,760 Da
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 NCBI Official Full Name    solute carrier family 2, facilitated glucose transporter member 4
 NCBI Official Synonym Full Names    solute carrier family 2 member 4
 NCBI Official Symbol    SLC2A4 [Similar Products]
 NCBI Official Synonym Symbols   
GLUT4
[Similar Products]
 NCBI Protein Information    solute carrier family 2, facilitated glucose transporter member 4
 UniProt Protein Name    Solute carrier family 2, facilitated glucose transporter member 4
 UniProt Synonym Protein Names   
Glucose transporter type 4, insulin-responsive; GLUT-4
 Protein Family    Solute carrier family
 UniProt Gene Name    SLC2A4 [Similar Products]
 UniProt Synonym Gene Names    GLUT4; GLUT-4 [Similar Products]
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 NCBI Summary for SLC2A4    This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
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 UniProt Comments for SLC2A4    GLUT4: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Its surface expression is regulated by insulin. Has two internalization sequences, a dileucine repeat present in the C-terminus and a FxxY motif in the amino-terminal end. Associates with an intracellular tubulo-vesicular compartment under low plasma conditions. The binding of insulin to the insulin receptor (a typosine kinase) leads to the rapid translocation of GLUT4 to the cell surface, increasing cellular glucose transport activity. Its translocation to the plasma membrane is also stimulated by exercise, but independent from insulin signaling. This insulin-independent pathway may be regulated by AMPK.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: clathrin-coated pit; clathrin-coated vesicle; cytoplasmic vesicle membrane; cytosol; endomembrane system; external side of plasma membrane; extracellular exosome; integral component of plasma membrane; membrane; membrane raft; multivesicular body; perinuclear region of cytoplasm; plasma membrane; T-tubule; trans-Golgi network transport vesicle; vesicle membrane

Molecular Function: D-glucose transmembrane transporter activity; glucose transmembrane transporter activity; protein binding

Biological Process: amylopectin biosynthetic process; brown fat cell differentiation; carbohydrate metabolic process; cellular response to hypoxia; cellular response to insulin stimulus; cellular response to osmotic stress; cellular response to tumor necrosis factor; glucose homeostasis; glucose import; glucose import in response to insulin stimulus; glucose transmembrane transport; glucose transport; response to ethanol

Disease: Diabetes Mellitus, Noninsulin-dependent
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 Research Articles on SLC2A4    1. Three polymorphisms (rs2654185, rs5415, and rs5417) in SLC2A4 were positively correlated with hip circumference and the rs2654185 locus was also positively associated with thigh circumference. Consumption of n-3 polyunsaturated fatty acids modifies associations between SCD, SLC2A4, and SREBF1 polymorphisms and anthropometric variables and metabolic phenotypes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SLC2A4 elisa kitPathways associated with SLC2A4 elisa kit
 Reference Product  PubMed Publications
 AKT2 elisa kit  >28 publications with SLC2A4 and AKT2
 TBC1D4 elisa kit  >27 publications with SLC2A4 and TBC1D4
 STXBP3 elisa kit  >15 publications with SLC2A4 and STXBP3
 RAB8A elisa kit  >5 publications with SLC2A4 and RAB8A
 STXBP4 elisa kit  >5 publications with SLC2A4 and STXBP4
 PRKAA2 elisa kit  >5 publications with SLC2A4 and PRKAA2
 RAB10 elisa kit  >5 publications with SLC2A4 and RAB10
 RAB14 elisa kit  >2 publications with SLC2A4 and RAB14
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Class I PI3K Signaling Events Mediated By Akt Pathway antibodies  Class I PI3K Signaling Events Mediated By Akt Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Facilitative Na+-independent Glucose Transporters Pathway antibodies  Facilitative Na+-independent Glucose Transporters Pathway Diagram
 Glucose Transport Pathway antibodies  Glucose Transport Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
Diseases associated with SLC2A4 elisa kitOrgans/Tissues associated with SLC2A4 elisa kit
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >768 publications with SLC2A4 and Insulin Resistance
 Hyperinsulinism Antibodies  >576 publications with SLC2A4 and Hyperinsulinism
 Diabetes Mellitus, Type 2 Antibodies  >282 publications with SLC2A4 and Diabetes Mellitus, Type 2
 Hyperglycemia Antibodies  >192 publications with SLC2A4 and Hyperglycemia
 Diabetes Mellitus, Experimental Antibodies  >166 publications with SLC2A4 and Diabetes Mellitus, Experimental
 Cardiovascular Diseases Antibodies  >138 publications with SLC2A4 and Cardiovascular Diseases
 Heart Diseases Antibodies  >102 publications with SLC2A4 and Heart Diseases
 Glucose Intolerance Antibodies  >76 publications with SLC2A4 and Glucose Intolerance
 Necrosis Antibodies  >76 publications with SLC2A4 and Necrosis
 Neoplasms Antibodies  >63 publications with SLC2A4 and Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2370 publications with SLC2A4 and Muscle
 Heart Antibodies  >376 publications with SLC2A4 and Heart
 Brain Antibodies  >93 publications with SLC2A4 and Brain
 Kidney Antibodies  >75 publications with SLC2A4 and Kidney
 Lung Antibodies  >22 publications with SLC2A4 and Lung
 Placenta Antibodies  >15 publications with SLC2A4 and Placenta
 Uterus Antibodies  >13 publications with SLC2A4 and Uterus
 Bone Antibodies  >11 publications with SLC2A4 and Bone
 Intestine Antibodies  >9 publications with SLC2A4 and Intestine
 Prostate Antibodies  >5 publications with SLC2A4 and Prostate
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