NP_001166864.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,720 Da
NCBI Official Full Name
hepatitis A virus cellular receptor 1 isoform a
NCBI Official Synonym Full Names
hepatitis A virus cellular receptor 1
NCBI Official Synonym Symbols
TIM; KIM1; TIM1; CD365; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1 [Similar Products]
NCBI Protein Information
hepatitis A virus cellular receptor 1
UniProt Protein Name
Hepatitis A virus cellular receptor 1
UniProt Synonym Protein Names
Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1
UniProt Synonym Gene Names
UniProt Entry Name
HAVR1_HUMAN
NCBI Summary for HAVCR1
The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. [provided by RefSeq, Apr 2015]
UniProt Comments for HAVCR1
TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q33.2
Cellular Component: integral to membrane
Molecular Function: viral receptor activity
Biological Process: entry of virus into host cell
Disease: Ige Responsiveness, Atopic
Research Articles on HAVCR1
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