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Hepc elisa kit :: Human Hepcidin (Hepc) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS454800
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $400 +1 FREE 8GB USB
96-Strip-Wells  /  $530 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,325 +2 FREE 8GB USB
10x96-Strip-Wells  /  $4,515 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hepcidin (Hepc), ELISA Kit

 Also Known As   

Human Hepcidin (Hepc) ELISA Kit

 Product Synonym Names    HAMP; HFE2B; PLTR; LEAP1; Hepcidin Antimicrobial Peptide; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor
 Product Gene Name   

Hepc elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    AF309489 mRNA
 3D Structure    ModBase 3D Structure for P81172
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 Species Reactivity    Human
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 Samples    Serum, Plasma, Urine, Tissue homogenates, Cell culture supernates, other biological fluids
 Assay Type    Sandwich
 Detection Range    62.5-4000pg/mL
 Sensitivity    23.5pg/mL
 Intra Assay    CV<10%
 Inter Assay    CV<12%
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 Preparation and Storage    For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of Hepc elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Hepc purchase    MBS454800 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hepcidin (Hepc) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5-4000pg/mL in biological research samples containing Hepc, with an estimated sensitivity of 23.5pg/mL. The ELISA analytical biochemical technique of the MBS454800 kit is based on Hepc antibody-Hepc antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Hepc antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Hepc. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Urine, Tissue homogenates, Cell culture supernates, other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of Hepc elisa kit    Hepc elisa kit Typical Testing Data/Standard Curve (for reference only) image
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NCBI/Uniprot data below describe general gene information for Hepc. It may not necessarily be applicable to this product.
 NCBI GI #    10863973
 NCBI GeneID    57817
 NCBI Accession #    NP_066998.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021175.3 [Other Products]
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 UniProt Primary Accession #    P81172 [Other Products]
 UniProt Secondary Accession #    Q1HE14; Q9BY68 [Other Products]
 UniProt Related Accession #    P81172 [Other Products]
 Molecular Weight    9,408 Da
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 NCBI Official Full Name    hepcidin preproprotein
 NCBI Official Synonym Full Names    hepcidin antimicrobial peptide
 NCBI Official Symbol    HAMP [Similar Products]
 NCBI Official Synonym Symbols   
HEPC; PLTR; HFE2B; LEAP1
[Similar Products]
 NCBI Protein Information    hepcidin
 UniProt Protein Name    Hepcidin
 UniProt Synonym Protein Names   
Liver-expressed antimicrobial peptide 1; LEAP-1
 Protein Family    Heparin-sulfate lyase
 UniProt Gene Name    HAMP [Similar Products]
 UniProt Synonym Gene Names    HEPC; LEAP1; LEAP-1; PLTR; Hepc25; Hepc20 [Similar Products]
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 NCBI Summary for Hepc    The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014]
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 UniProt Comments for Hepc    Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).
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 Research Articles on Hepc    1. serum NGAL and hepcidin levels might be valuable for the evaluation of inflammation in chronic kidney disease, not related through iron metabolism
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Hepc elisa kitPathways associated with Hepc elisa kit
 Reference Product  PubMed Publications
 HFE elisa kit  >339 publications with Hepc and HFE
 BMP6 elisa kit  >84 publications with Hepc and BMP6
 STAT3 elisa kit  >74 publications with Hepc and STAT3
 SLC40A1 elisa kit  >56 publications with Hepc and SLC40A1
 IL6 elisa kit  >52 publications with Hepc and IL6
 GDF15 elisa kit  >36 publications with Hepc and GDF15
 SLC11A2 elisa kit  >6 publications with Hepc and SLC11A2
 CREB3L3 elisa kit  >3 publications with Hepc and CREB3L3
 ATOH8 elisa kit  >1 publications with Hepc and ATOH8
 Products by Pathway  Pathway Diagram
 Hfe Effect On Hepcidin Production Pathway antibodies  Hfe Effect On Hepcidin Production Pathway Diagram
 Iron Metabolism In Placenta Pathway antibodies  Iron Metabolism In Placenta Pathway Diagram
Diseases associated with Hepc elisa kitOrgans/Tissues associated with Hepc elisa kit
 Disease Name  Pubmed Publications
 Anemia Antibodies  >919 publications with Hepc and Anemia
 Iron Overload Antibodies  >757 publications with Hepc and Iron Overload
 Inflammation Antibodies  >675 publications with Hepc and Inflammation
 Hemochromatosis Antibodies  >534 publications with Hepc and Hemochromatosis
 Liver Diseases Antibodies  >322 publications with Hepc and Liver Diseases
 Kidney Diseases Antibodies  >193 publications with Hepc and Kidney Diseases
 Disease Models, Animal Antibodies  >165 publications with Hepc and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >126 publications with Hepc and Cardiovascular Diseases
 Necrosis Antibodies  >95 publications with Hepc and Necrosis
 beta-Thalassemia Antibodies  >89 publications with Hepc and beta-Thalassemia
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >949 publications with Hepc and Liver
 Spleen Antibodies  >151 publications with Hepc and Spleen
 Brain Antibodies  >61 publications with Hepc and Brain
 Lung Antibodies  >38 publications with Hepc and Lung
 Eye Antibodies  >23 publications with Hepc and Eye
 Placenta Antibodies  >21 publications with Hepc and Placenta
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