|
| Product Name
|
|
Hyaluronan-Mediated Motility Receptor (HMMR/CD168), ELISA Kit
|
| Also Known As
|
|
Human Hyaluronan-Mediated Motility Receptor ELISA Kit
|
| Product Gene Name
|
|
|
[Similar Products]
|
| Research Use Only
|
|
For Research Use Only. Not for use in diagnostic procedures.
|
 TOP
|
| Request for Current Manual Insert
|
|
 |
|
| Chromosome Location
|
|
Chromosome: 5; NC_000005.9 (162887517..162918951). Location: 5q33.2-qter
|
| OMIM
|
|
600936
|
| 3D Structure
|
|
ModBase 3D Structure for O75330
|
|
| Species Reactivity
|
|
Human
|
|
|
|
|
| Assay Type
|
|
Sandwich
|
|
|
| Preparation and Storage
|
|
Store all reagents at 2-8 degree C
|
| Product Note
|
|
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
|
| Other Notes
|
|
Small volumes of HMMR/CD168 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
|
| Searchable Terms for HMMR/CD168 purchase
|
|
MBS024203 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hyaluronan-Mediated Motility Receptor (HMMR/CD168) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HMMR/CD168. The ELISA analytical biochemical technique of the MBS024203 kit is based on HMMR/CD168 antibody-HMMR/CD168 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HMMR/CD168 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HMMR/CD168. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
|
|
TOP
|
|
| NCBI/Uniprot data below describe general gene information for HMMR/CD168. It may not necessarily be applicable to this product. |
| NCBI GI #
|
|
217416398
|
| NCBI GeneID
|
|
3161
|
| NCBI Accession #
|
|
NP_036617.2
|
[Other Products]
|
| NCBI GenBank Nucleotide #
|
|
NM_012485.2
|
[Other Products]
|
|
|
| UniProt Primary Accession #
|
|
O75330
|
[Other Products]
|
| UniProt Secondary Accession #
|
|
Q32N02; Q92767; A8K3G2; B4E114; D3DQK9; D3DQL0; E9PCS0
|
[Other Products]
|
| UniProt Related Accession #
|
|
O75330
|
[Other Products]
|
| Molecular Weight
|
|
84,100 Da
|
|
TOP
|
| NCBI Official Full Name
|
|
hyaluronan mediated motility receptor isoform c
|
| NCBI Official Synonym Full Names
|
|
hyaluronan-mediated motility receptor (RHAMM)
|
| NCBI Official Symbol
|
|
HMMR
|
[Similar Products]
|
| NCBI Official Synonym Symbols
|
|
CD168; IHABP; RHAMM
|
[Similar Products]
|
| NCBI Protein Information
|
|
hyaluronan mediated motility receptor; receptor for hyaluronan-mediated motility; intracellular hyaluronic acid-binding protein
|
| UniProt Protein Name
|
|
Hyaluronan mediated motility receptor
|
| UniProt Synonym Protein Names
|
|
Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility
|
| Protein Family
|
|
Hyaluronan-mediated motility receptor
|
| UniProt Gene Name
|
|
HMMR
|
[Similar Products]
|
| UniProt Synonym Gene Names
|
|
IHABP; RHAMM
|
[Similar Products]
|
| UniProt Entry Name
|
|
HMMR_HUMAN
|
|
|
| NCBI Summary for HMMR/CD168
|
|
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]
|
|
|
| UniProt Comments for HMMR/CD168
|
|
HMMR: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 5q34
Cellular Component: cell surface; membrane; cytoplasm; plasma membrane
Molecular Function: hyaluronic acid binding
Biological Process: glycosaminoglycan metabolic process; carbohydrate metabolic process; pathogenesis; hyaluronan metabolic process; hyaluronan catabolic process
Disease: Breast Cancer
|
|
TOP
|
|
| Research Articles on HMMR/CD168
|
|
1. RHAMM does not fulfill the criteria of an ideal target antigen for immunotherapy of acute myeloid leukemia.
|
|
TOP
|
| Precautions
|
|
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
|
| Disclaimer
|
|
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
|
|
TOP
|
|
| Products associated with HMMR/CD168 elisa kit | Pathways associated with HMMR/CD168 elisa kit |
|
|
|
| Diseases associated with HMMR/CD168 elisa kit | Organs/Tissues associated with HMMR/CD168 elisa kit |
|
|
|
|
|
|
TOP
|
ELISA Kit 
