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IGF-1 elisa kit :: Human IGF-1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9501951
Testing Data
Unit / Price
96-Strip-Wells  /  $440 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IGF-1, ELISA Kit

★Popular Item★
 Also Known As   

IGF-1 (Human) OmniKine ELISA Kit

 Product Synonym Names    Insulin-like growth factor I; Mechano growth factor; Somatomedin-C
 Product Gene Name   

IGF-1 elisa kit

[Similar Products]
 Product Synonym Gene Name    IGF1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    X00173 mRNA
 3D Structure    ModBase 3D Structure for P05019
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 Species Reactivity    Human
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 Specificity    The OmniKine Human IGF-1 ELISA is capable of recognizing both recombinant and naturally produced Human IGF-1 proteins.The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: IGF-1sR, IGF-2, IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, IGFBP-6
Murine:IGF-1, IGF-2
 Form/Format    12 x 8-Well Microstrips
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 Samples    Plasma, serum, lysate
 Assay Type    Sandwich ELISA
 Detection Range    32-2000 pg/ml
 Sensitivity    32-2000 pg/ml
 Detection Method    Colorimetric 450 nm
 Subtype    None
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 Preparation and Storage    Store at 4 degree C for 6 months.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IGF-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IGF-1 purchase    MBS9501951 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IGF-1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 32-2000 pg/ml in biological research samples containing IGF-1, with an estimated sensitivity of 32-2000 pg/ml. The ELISA analytical biochemical technique of the MBS9501951 kit is based on IGF-1 antibody-IGF-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGF-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGF-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Plasma, serum, lysate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Testing Data of IGF-1 elisa kit    The OmniKine Human IGF-1 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IGF-1 proteins within the range of 32-2000 pg/ml.
IGF-1 elisa kit Testing Data image
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Sample Manual Insert of MBS9501951. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IGF-1. It may not necessarily be applicable to this product.
 NCBI GI #    11024682
 NCBI GeneID    3479
 NCBI Accession #    NP_000609.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000618.4 [Other Products]
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 UniProt Primary Accession #    P05019 [Other Products]
 UniProt Secondary Accession #    P01343; Q14620; B2RWM7; E9PD02 [Other Products]
 UniProt Related Accession #    P05019 [Other Products]
 Molecular Weight    17,762 Da
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 NCBI Official Full Name    insulin-like growth factor I isoform 4 preproprotein
 NCBI Official Synonym Full Names    insulin like growth factor 1
 NCBI Official Symbol    IGF1 [Similar Products]
 NCBI Official Synonym Symbols   
MGF; IGFI; IGF-I
[Similar Products]
 NCBI Protein Information    insulin-like growth factor I
 UniProt Protein Name    Insulin-like growth factor I
 UniProt Synonym Protein Names   
Mechano growth factor; MGF; Somatomedin-C
 UniProt Gene Name    IGF1 [Similar Products]
 UniProt Synonym Gene Names    IBP1; IGF-I; MGF [Similar Products]
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 NCBI Summary for IGF-1    The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
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 UniProt Comments for IGF-1    IGF1: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency). IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. Belongs to the insulin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q23.2

Cellular Component: extracellular region; extracellular space; insulin-like growth factor binding protein complex; plasma membrane

Molecular Function: growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; integrin binding; protein binding

Biological Process: activation of MAPK activity; activation of protein kinase B activity; cell activation; cell motility; cell proliferation; cellular protein metabolic process; DNA replication; glycolate metabolic process; insulin-like growth factor receptor signaling pathway; muscle hypertrophy; muscle organ development; myoblast differentiation; myoblast proliferation; myotube cell development; negative regulation of apoptosis; phosphoinositide 3-kinase cascade; phosphoinositide-mediated signaling; platelet degranulation; positive regulation of activated T cell proliferation; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of DNA binding; positive regulation of DNA replication; positive regulation of epithelial cell proliferation; positive regulation of fibroblast proliferation; positive regulation of glucose import; positive regulation of glycogen biosynthetic process; positive regulation of glycolysis; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of MAPK cascade; positive regulation of mitotic nuclear division; positive regulation of osteoblast differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein import into nucleus, translocation; positive regulation of protein secretion; positive regulation of Ras protein signal transduction; positive regulation of smooth muscle cell migration; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; positive regulation of tyrosine phosphorylation of STAT protein; protein kinase B signaling; protein stabilization; proteoglycan biosynthetic process; Ras protein signal transduction; regulation of gene expression; regulation of multicellular organism growth; response to heat; satellite cell compartment self-renewal involved in skeletal muscle regeneration; signal transduction; skeletal system development

Disease: Insulin-like Growth Factor I Deficiency
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 Research Articles on IGF-1    1. We discuss methodological shortcomings of our study and potential differences in the temporal dynamics of how IGF-1, VEGF and BDNF may be affected by exercise and to what extent these differences may have led to the negative findings reported here.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IGF-1 elisa kitPathways associated with IGF-1 elisa kit
 Reference Product  PubMed Publications
 IGF1R elisa kit  >441 publications with IGF-1 and IGF1R
 IGFBP3 elisa kit  >224 publications with IGF-1 and IGFBP3
 IGFBP1 elisa kit  >72 publications with IGF-1 and IGFBP1
 IRS1 elisa kit  >70 publications with IGF-1 and IRS1
 IGFBP2 elisa kit  >60 publications with IGF-1 and IGFBP2
 IRS2 elisa kit  >41 publications with IGF-1 and IRS2
 INSR elisa kit  >40 publications with IGF-1 and INSR
 IGFBP5 elisa kit  >28 publications with IGF-1 and IGFBP5
 IGFBP4 elisa kit  >23 publications with IGF-1 and IGFBP4
 IGFBP6 elisa kit  >8 publications with IGF-1 and IGFBP6
 Products by Pathway  Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
Diseases associated with IGF-1 elisa kitOrgans/Tissues associated with IGF-1 elisa kit
 Disease Name  Pubmed Publications
 Acromegaly Antibodies  >129 publications with IGF-1 and Acromegaly
 Breast Neoplasms Antibodies  >112 publications with IGF-1 and Breast Neoplasms
 Inflammation Antibodies  >87 publications with IGF-1 and Inflammation
 Female Urogenital Diseases Antibodies  >87 publications with IGF-1 and Female Urogenital Diseases
 Liver Diseases Antibodies  >66 publications with IGF-1 and Liver Diseases
 Adenoma Antibodies  >59 publications with IGF-1 and Adenoma
 Prostatic Neoplasms Antibodies  >51 publications with IGF-1 and Prostatic Neoplasms
 Necrosis Antibodies  >45 publications with IGF-1 and Necrosis
 Pituitary Neoplasms Antibodies  >45 publications with IGF-1 and Pituitary Neoplasms
 Hypertension Antibodies  >39 publications with IGF-1 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >609 publications with IGF-1 and Blood
 Muscle Antibodies  >286 publications with IGF-1 and Muscle
 Liver Antibodies  >256 publications with IGF-1 and Liver
 Bone Antibodies  >254 publications with IGF-1 and Bone
 Brain Antibodies  >203 publications with IGF-1 and Brain
 Vascular Antibodies  >117 publications with IGF-1 and Vascular
 Ovary Antibodies  >110 publications with IGF-1 and Ovary
 Heart Antibodies  >106 publications with IGF-1 and Heart
 Connective Tissue Antibodies  >103 publications with IGF-1 and Connective Tissue
 Lung Antibodies  >81 publications with IGF-1 and Lung
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