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IGFALS elisa kit :: Human IGFALS ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2500615
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Human IGFALS(Insulin Like Growth Factor Binding Protein, Acid Labile Subunit)ELISA Kit

 Product Gene Name   

IGFALS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    601489
 3D Structure    ModBase 3D Structure for P35858
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human IGFALS. No significant cross-reactivity or interference between Human IGFALS and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human IGFALS and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    1.563-100ng/mL
 Sensitivity    Min: 0.938ng/mL; Max: 100ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IGFALS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IGFALS purchase    MBS2500615 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IGFALS, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.563-100ng/mL in biological research samples containing IGFALS, with an estimated sensitivity of Min: 0.938ng/mL; Max: 100ng/mL. The ELISA analytical biochemical technique of the MBS2500615 kit is based on IGFALS antibody-IGFALS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFALS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFALS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IGFALS elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IGFALS in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IGFALS. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human IGFALS and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human IGFALS, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human IGFALS. You can calculate the concentration of Human IGFALS in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of IGFALS elisa kit    IGFALS elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2500615. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IGFALS. It may not necessarily be applicable to this product.
 NCBI GI #    4826772
 NCBI GeneID    3483
 NCBI Accession #    NP_004961.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004970.2 [Other Products]
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 UniProt Primary Accession #    P35858 [Other Products]
 UniProt Secondary Accession #    B4DZY8; E9PGU3 [Other Products]
 UniProt Related Accession #    P35858 [Other Products]
 Molecular Weight    70,236 Da
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 NCBI Official Full Name    insulin-like growth factor-binding protein complex acid labile subunit isoform 2
 NCBI Official Synonym Full Names    insulin-like growth factor binding protein, acid labile subunit
 NCBI Official Symbol    IGFALS [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    insulin-like growth factor-binding protein complex acid labile subunit; insulin-like growth factor binding protein complex acid labile chain
 UniProt Protein Name    Insulin-like growth factor-binding protein complex acid labile subunit
 Protein Family    Insulin-like growth factor-binding protein complex acid labile
 UniProt Gene Name    IGFALS [Similar Products]
 UniProt Synonym Gene Names    ALS; ALS [Similar Products]
 UniProt Entry Name    ALS_HUMAN
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 NCBI Summary for IGFALS    The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
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 UniProt Comments for IGFALS    IGFALS: Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.

Protein type: Secreted; Secreted, signal peptide; Cell adhesion

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nucleoplasm; extracellular space; extracellular region

Molecular Function: insulin-like growth factor binding

Biological Process: cellular protein metabolic process; cell adhesion; signal transduction

Disease: Acid-labile Subunit Deficiency
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 Research Articles on IGFALS    1. Heterozygous IGFALS gene variants could be responsible for short stature in a subset of idiopathic short stature children with diminished levels of IGF-1, IGFBP-3 and ALS.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IGFALS elisa kitPathways associated with IGFALS elisa kit
 Reference Product  PubMed Publications
 IGF1 elisa kit  >24 publications with IGFALS and IGF1
 IGFBP3 elisa kit  >20 publications with IGFALS and IGFBP3
 IGF2 elisa kit  >4 publications with IGFALS and IGF2
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies  Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
Diseases associated with IGFALS elisa kitOrgans/Tissues associated with IGFALS elisa kit
 Disease Name  Pubmed Publications
 Growth Disorders Antibodies  >20 publications with IGFALS and Growth Disorders
 Insulin Resistance Antibodies  >10 publications with IGFALS and Insulin Resistance
 Puberty, Delayed Antibodies  >4 publications with IGFALS and Puberty, Delayed
 Congenital Abnormalities Antibodies  >4 publications with IGFALS and Congenital Abnormalities
 Liver Diseases Antibodies  >3 publications with IGFALS and Liver Diseases
 Weight Gain Antibodies  >3 publications with IGFALS and Weight Gain
 Heart Diseases Antibodies  >2 publications with IGFALS and Heart Diseases
 Fatty Liver Antibodies  >2 publications with IGFALS and Fatty Liver
 Carcinoma, Hepatocellular Antibodies  >2 publications with IGFALS and Carcinoma, Hepatocellular
 Inflammation Antibodies  >2 publications with IGFALS and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >8 publications with IGFALS and Liver
 Eye Antibodies  >1 publications with IGFALS and Eye
 Brain Antibodies  >1 publications with IGFALS and Brain
 Mammary Gland Antibodies  >1 publications with IGFALS and Mammary Gland
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