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IL18 elisa kit :: Human IL-18 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS824968
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
96 Tests  /  $470 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL-18 (IL18), ELISA Kit

★Popular Item★
 Also Known As   

Human IL-18 ELISA Kit

 Product Synonym Names    IGIF; IL1F4; Interleukin-18; IL-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
 Product Gene Name   

IL18 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600953
 3D Structure    ModBase 3D Structure for Q14116
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 Species Reactivity    Human
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 Specificity    The Human IL-18 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-18 proteins within the range of 39 pg/ml - 2500 pg/ml.
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 Samples    Cell Culture Supernatants, Serum, Plasma, Tissue Homogenates.
 Assay Type    Quantitative ELISA
 Sensitivity    Typically less than 20 pg/ml.
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 Preparation and Storage    Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL18 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL18 purchase    MBS824968 is a ready-to-use microwell, strip-or-full plate Quantitative ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IL-18 (IL18) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL18, with an estimated sensitivity of Typically less than 20 pg/ml. The ELISA analytical biochemical technique of the MBS824968 kit is based on IL18 antibody-IL18 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL18 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL18. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Cell Culture Supernatants, Serum, Plasma, Tissue Homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL18 elisa kit

   Background: Interleukin (IL)-18, also called Interferon-gamma-inducing factor (IGIF), augments natural killer (NK) activity in spleen cells. The gene encodes a precursor protein of 192 amino acids and a mature protein of 157 amino acids. IL-18 is a recently discovered cytokine that modulates both T helper type 1 (Th1) and Th2 responses. IL-18 is a potent proinflammatory cytokine with potential atherogenic properties. It is highly expressed in the atherosclerotic plaques compared with control normal arteries and is localized mainly in plaque macrophages.
 Applications Tested/Suitable for IL18 elisa kit   

Sandwich ELISA (SE)

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 Typical Testing Data/Standard Curve (for reference only) of IL18 elisa kit    IL18 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS824968. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL18. It may not necessarily be applicable to this product.
 NCBI GI #    342349321
 NCBI GeneID    3606
 NCBI Accession #    NP_001230140.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243211.1 [Other Products]
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 UniProt Primary Accession #    Q14116 [Other Products]
 UniProt Secondary Accession #    O75599; Q6FGY3; Q6WWJ7 [Other Products]
 UniProt Related Accession #    Q14116 [Other Products]
 Molecular Weight    21,896 Da
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 NCBI Official Full Name    interleukin-18 isoform 2 proprotein
 NCBI Official Synonym Full Names    interleukin 18
 NCBI Official Symbol    IL18 [Similar Products]
 NCBI Official Synonym Symbols   
IGIF; IL-18; IL-1g; IL1F4
[Similar Products]
 NCBI Protein Information    interleukin-18; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor)
 UniProt Protein Name    Interleukin-18
 UniProt Synonym Protein Names   
Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
 Protein Family    Interleukin
 UniProt Gene Name    IL18 [Similar Products]
 UniProt Synonym Gene Names    IGIF; IL1F4; IL-18; IFN-gamma-inducing factor; IL-1 gamma [Similar Products]
 UniProt Entry Name    IL18_HUMAN
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 NCBI Summary for IL18    The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
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 UniProt Comments for IL18    IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 11q22.2-q22.3

Cellular Component: extracellular space; extracellular region; cytosol

Molecular Function: protein binding; cytokine activity

Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of activated T cell proliferation; chemokine biosynthetic process; cell-cell signaling; lipopolysaccharide-mediated signaling pathway; granulocyte macrophage colony-stimulating factor biosynthetic process; angiogenesis; inflammatory response; regulation of cell adhesion; positive regulation of interleukin-17 production; positive regulation of natural killer cell proliferation; T-helper 1 type immune response; interleukin-2 biosynthetic process; T-helper 2 type immune response; MAPKKK cascade; interleukin-13 biosynthetic process; sleep; positive regulation of tissue remodeling; positive regulation of interferon-gamma production; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation; positive regulation of inflammatory response
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 Research Articles on IL18    1. THP-1 monocyte-secreted IL-1beta/IL-18 promotes vascular smooth muscle cell proliferation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL18 elisa kitPathways associated with IL18 elisa kit
 Reference Product  PubMed Publications
 CASP1 elisa kit  >524 publications with IL18 and CASP1
 IL10 elisa kit  >298 publications with IL18 and IL10
 IL18R1 elisa kit  >220 publications with IL18 and IL18R1
 IL13 elisa kit  >90 publications with IL18 and IL13
 IL6 elisa kit  >73 publications with IL18 and IL6
 IL18RAP elisa kit  >35 publications with IL18 and IL18RAP
 IL1B elisa kit  >30 publications with IL18 and IL1B
 IFNG elisa kit  >23 publications with IL18 and IFNG
 IL18BP elisa kit  >19 publications with IL18 and IL18BP
 CCR5 elisa kit  >18 publications with IL18 and CCR5
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cellular Roles Of Anthrax Toxin Pathway antibodies  Cellular Roles Of Anthrax Toxin Pathway Diagram
 Corticotropin-releasing Hormone Pathway antibodies  Corticotropin-releasing Hormone Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
Diseases associated with IL18 elisa kitOrgans/Tissues associated with IL18 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1211 publications with IL18 and Inflammation
 Necrosis Antibodies  >798 publications with IL18 and Necrosis
 Cardiovascular Diseases Antibodies  >434 publications with IL18 and Cardiovascular Diseases
 Lung Diseases Antibodies  >328 publications with IL18 and Lung Diseases
 Kidney Diseases Antibodies  >312 publications with IL18 and Kidney Diseases
 Hypersensitivity Antibodies  >266 publications with IL18 and Hypersensitivity
 Liver Diseases Antibodies  >237 publications with IL18 and Liver Diseases
 Arthritis, Rheumatoid Antibodies  >221 publications with IL18 and Arthritis, Rheumatoid
 Heart Diseases Antibodies  >204 publications with IL18 and Heart Diseases
 Hypersensitivity, Immediate Antibodies  >188 publications with IL18 and Hypersensitivity, Immediate
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >408 publications with IL18 and Liver
 Lung Antibodies  >317 publications with IL18 and Lung
 Heart Antibodies  >218 publications with IL18 and Heart
 Bone Antibodies  >215 publications with IL18 and Bone
 Brain Antibodies  >213 publications with IL18 and Brain
 Skin Antibodies  >213 publications with IL18 and Skin
 Intestine Antibodies  >158 publications with IL18 and Intestine
 Bone Marrow Antibodies  >144 publications with IL18 and Bone Marrow
 Muscle Antibodies  >133 publications with IL18 and Muscle
 Connective Tissue Antibodies  >74 publications with IL18 and Connective Tissue
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