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INS elisa kit :: Human Insulin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS028989 INS elisa kit
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Insulin, ELISA Kit

★Popular Item★
 Also Known As   

Human Insulin ELISA Kit

 Product Gene Name   

INS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 11; NC_000011.9 (2181009..2182439, complement). Location: 11p15.5
 OMIM    125852
 3D Structure    ModBase 3D Structure for P01308
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples.
 Assay Type    Sandwich
 Detection Range    3.12 mIU/L - 100 mIU/L.
 Sensitivity    1.0 mIU/L.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of INS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for INS purchase    MBS028989 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12 mIU/L - 100 mIU/L in biological research samples containing INS, with an estimated sensitivity of 1.0 mIU/L. The ELISA analytical biochemical technique of the MBS028989 kit is based on INS antibody-INS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect INS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, INS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for INS elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of INS (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
NCBI/Uniprot data below describe general gene information for INS. It may not necessarily be applicable to this product.
 NCBI GI #    386828
 NCBI GeneID    3630
 NCBI Accession #    AAA59172.1 [Other Products]
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 UniProt Primary Accession #    P01308 [Other Products]
 UniProt Secondary Accession #    Q5EEX2 [Other Products]
 UniProt Related Accession #    P01308 [Other Products]
 Molecular Weight    11,981 Da
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 NCBI Official Full Name    insulin
 NCBI Official Synonym Full Names    insulin
 NCBI Official Symbol    INS [Similar Products]
 NCBI Official Synonym Symbols   
ILPR; IRDN; IDDM2; MODY10
[Similar Products]
 NCBI Protein Information    insulin; proinsulin; preproinsulin
 UniProt Protein Name    Insulin
 Protein Family    Insulin
 UniProt Gene Name    INS [Similar Products]
 UniProt Entry Name    INS_HUMAN
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 NCBI Summary for INS    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
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 UniProt Comments for INS    Insulin: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds. Belongs to the insulin family.

Protein type: Secreted; Hormone; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: extracellular space; Golgi lumen; endoplasmic reticulum lumen; extracellular region

Molecular Function: identical protein binding; insulin-like growth factor receptor binding; protein binding; protease binding; hormone activity; insulin receptor binding

Biological Process: positive regulation of nitric oxide biosynthetic process; glucose homeostasis; positive regulation of vasodilation; activation of NF-kappaB transcription factor; negative regulation of protein oligomerization; positive regulation of glucose import; regulation of protein localization; cell-cell signaling; negative regulation of gluconeogenesis; acute-phase response; regulation of transmembrane transporter activity; negative regulation of NAD(P)H oxidase activity; positive regulation of mitosis; activation of protein kinase B; positive regulation of nitric-oxide synthase activity; negative regulation of acute inflammatory response; glucose metabolic process; positive regulation of lipid biosynthetic process; positive regulation of cell growth; positive regulation of protein amino acid autophosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of peptidyl-tyrosine phosphorylation; regulation of amino acid metabolic process; negative regulation of protein catabolic process; positive regulation of cell differentiation; negative regulation of glycogen catabolic process; wound healing; positive regulation of cellular protein metabolic process; positive regulation of glycogen biosynthetic process; glucose transport; regulation of protein secretion; negative regulation of lipid catabolic process; regulation of transcription, DNA-dependent; negative regulation of vasodilation; positive regulation of MAPKKK cascade; positive regulation of cell proliferation; negative regulation of proteolysis; negative regulation of protein secretion; MAPKKK cascade; negative regulation of fatty acid metabolic process; alpha-beta T cell activation; endocrine pancreas development; G-protein coupled receptor protein signaling pathway; positive regulation of protein kinase B signaling cascade; cellular protein metabolic process; fatty acid homeostasis; positive regulation of glycolysis; energy reserve metabolic process; insulin receptor signaling pathway; positive regulation of insulin receptor signaling pathway; regulation of insulin secretion; positive regulation of DNA replication; positive regulation of cell migration; positive regulation of cytokine secretion

Disease: Diabetes Mellitus, Insulin-dependent, 2; Diabetes Mellitus, Permanent Neonatal; Hyperproinsulinemia; Maturity-onset Diabetes Of The Young, Type 10
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 Research Articles on INS    1. Elevated C-peptide and insulin predict increased risk of colorectal adenomas in normal mucosa.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with INS elisa kitPathways associated with INS elisa kit
 Reference Product  PubMed Publications
 IRS1 elisa kit  >30 publications with INS and IRS1
 FOXO1 elisa kit  >28 publications with INS and FOXO1
 INSR elisa kit  >25 publications with INS and INSR
 IRS2 elisa kit  >23 publications with INS and IRS2
 AKT1 elisa kit  >14 publications with INS and AKT1
 GRB2 elisa kit  >11 publications with INS and GRB2
 IDE elisa kit  >7 publications with INS and IDE
 IGFBP1 elisa kit  >4 publications with INS and IGFBP1
 PTPN1 elisa kit  >3 publications with INS and PTPN1
 AKT2 elisa kit  >2 publications with INS and AKT2
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
Diseases associated with INS elisa kitOrgans/Tissues associated with INS elisa kit
 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >983 publications with INS and Metabolic Diseases
 Diabetes Mellitus Antibodies  >802 publications with INS and Diabetes Mellitus
 Insulin Resistance Antibodies  >297 publications with INS and Insulin Resistance
 Diabetes Mellitus, Type 2 Antibodies  >269 publications with INS and Diabetes Mellitus, Type 2
 Obesity Antibodies  >219 publications with INS and Obesity
 Hyperinsulinism Antibodies  >197 publications with INS and Hyperinsulinism
 Hyperglycemia Antibodies  >193 publications with INS and Hyperglycemia
 Hypertension Antibodies  >119 publications with INS and Hypertension
 Polycystic Ovary Syndrome Antibodies  >50 publications with INS and Polycystic Ovary Syndrome
 Hypoglycemia Antibodies  >45 publications with INS and Hypoglycemia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1432 publications with INS and Blood
 Pancreas Antibodies  >1412 publications with INS and Pancreas
 Brain Antibodies  >698 publications with INS and Brain
 Muscle Antibodies  >536 publications with INS and Muscle
 Liver Antibodies  >384 publications with INS and Liver
 Heart Antibodies  >292 publications with INS and Heart
 Vascular Antibodies  >259 publications with INS and Vascular
 Kidney Antibodies  >258 publications with INS and Kidney
 Nerve Antibodies  >247 publications with INS and Nerve
 Bone Antibodies  >150 publications with INS and Bone
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