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INS elisa kit :: Human Insulin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS580023 INS elisa kit
Unit / Price
96-Strip-Wells  /  $235 +1 FREE 8GB USB
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 Product Name   

Insulin, ELISA Kit

★Popular Item★
 Also Known As   

Insulin ELISA Kit

 Product Synonym Names    Insulin ELISA
 Product Gene Name   

INS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    125852
 3D Structure    ModBase 3D Structure for P01308
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 Species Reactivity    Human
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 Samples    Human serum or plasma
 Intended Uses    The Insulin ELISA Kit is intended for the quantitative measurement Insulin in human serum or plasma. For research use only.
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 Preparation and Storage    Product should be stored at 2-8 degree C. Product is stable for 24 months from the date of manufacturing.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of INS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for INS purchase    MBS580023 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing INS. The ELISA analytical biochemical technique of the MBS580023 kit is based on INS antibody-INS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect INS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, INS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Human serum or plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for INS elisa kit    Diabetes Markers
Sample Manual Insert of MBS580023. Click to request current manual
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NCBI/Uniprot data below describe general gene information for INS. It may not necessarily be applicable to this product.
 NCBI GI #    386828
 NCBI GeneID    3630
 NCBI Accession #    AAA59172.1 [Other Products]
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 UniProt Primary Accession #    P01308 [Other Products]
 UniProt Secondary Accession #    Q5EEX2 [Other Products]
 UniProt Related Accession #    P01308 [Other Products]
 Molecular Weight    21,537 Da [Similar Products]
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 NCBI Official Full Name    insulin
 NCBI Official Synonym Full Names    insulin
 NCBI Official Symbol    INS [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    insulin; preproinsulin
 UniProt Protein Name    Insulin
 Protein Family    Insulin
 UniProt Gene Name    INS [Similar Products]
 UniProt Entry Name    INS_HUMAN
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 NCBI Summary for INS    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
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 UniProt Comments for INS    Insulin: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Heterodimer of a B chain and an A chain linked by two disulfide bonds. Belongs to the insulin family.

Protein type: Secreted; Hormone; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: extracellular space; Golgi lumen; endoplasmic reticulum lumen; extracellular region

Molecular Function: insulin-like growth factor receptor binding; identical protein binding; protein binding; protease binding; hormone activity; insulin receptor binding

Biological Process: positive regulation of nitric oxide biosynthetic process; glucose homeostasis; positive regulation of vasodilation; activation of NF-kappaB transcription factor; positive regulation of glucose import; negative regulation of protein oligomerization; regulation of protein localization; cell-cell signaling; negative regulation of gluconeogenesis; acute-phase response; regulation of transmembrane transporter activity; negative regulation of NAD(P)H oxidase activity; positive regulation of mitosis; activation of protein kinase B; positive regulation of nitric-oxide synthase activity; negative regulation of acute inflammatory response; glucose metabolic process; positive regulation of lipid biosynthetic process; positive regulation of protein amino acid autophosphorylation; positive regulation of cell growth; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of protein catabolic process; regulation of amino acid metabolic process; positive regulation of cell differentiation; negative regulation of glycogen catabolic process; wound healing; positive regulation of glycogen biosynthetic process; positive regulation of cellular protein metabolic process; glucose transport; regulation of protein secretion; positive regulation of MAPKKK cascade; negative regulation of vasodilation; regulation of transcription, DNA-dependent; negative regulation of lipid catabolic process; positive regulation of cell proliferation; negative regulation of proteolysis; negative regulation of protein secretion; MAPKKK cascade; alpha-beta T cell activation; negative regulation of fatty acid metabolic process; endocrine pancreas development; G-protein coupled receptor protein signaling pathway; positive regulation of protein kinase B signaling cascade; cellular protein metabolic process; fatty acid homeostasis; positive regulation of glycolysis; insulin receptor signaling pathway; energy reserve metabolic process; positive regulation of insulin receptor signaling pathway; regulation of insulin secretion; positive regulation of DNA replication; positive regulation of cytokine secretion; positive regulation of cell migration

Disease: Diabetes Mellitus, Insulin-dependent, 2; Diabetes Mellitus, Permanent Neonatal; Hyperproinsulinemia; Maturity-onset Diabetes Of The Young, Type 10
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 Research Articles on INS    1. Data suggest serum insulin/proinsulin levels are highest at birth, decline by age 3 months, and remain stable as child approaches age 2 years; no differences are exhibited in children who later develop autoantibodies against insulin-secreting cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with INS elisa kitPathways associated with INS elisa kit
 Reference Product  PubMed Publications
 PDX1 elisa kit  >61 publications with INS and PDX1
 IRS1 elisa kit  >38 publications with INS and IRS1
 FOXO1 elisa kit  >34 publications with INS and FOXO1
 INSR elisa kit  >33 publications with INS and INSR
 IRS2 elisa kit  >30 publications with INS and IRS2
 IGF1R elisa kit  >24 publications with INS and IGF1R
 AKT1 elisa kit  >18 publications with INS and AKT1
 IGFBP1 elisa kit  >8 publications with INS and IGFBP1
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Arf6 Trafficking Events Pathway antibodies  Arf6 Trafficking Events Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
Diseases associated with INS elisa kitOrgans/Tissues associated with INS elisa kit
 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >1158 publications with INS and Metabolic Diseases
 Diabetes Mellitus Antibodies  >965 publications with INS and Diabetes Mellitus
 Insulin Resistance Antibodies  >346 publications with INS and Insulin Resistance
 Diabetes Mellitus, Type 2 Antibodies  >332 publications with INS and Diabetes Mellitus, Type 2
 Obesity Antibodies  >259 publications with INS and Obesity
 Hyperglycemia Antibodies  >236 publications with INS and Hyperglycemia
 Hyperinsulinism Antibodies  >225 publications with INS and Hyperinsulinism
 Hypertension Antibodies  >135 publications with INS and Hypertension
 Polycystic Ovary Syndrome Antibodies  >60 publications with INS and Polycystic Ovary Syndrome
 Hypoglycemia Antibodies  >53 publications with INS and Hypoglycemia
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >1626 publications with INS and Pancreas
 Blood Antibodies  >1597 publications with INS and Blood
 Brain Antibodies  >812 publications with INS and Brain
 Muscle Antibodies  >575 publications with INS and Muscle
 Liver Antibodies  >427 publications with INS and Liver
 Heart Antibodies  >316 publications with INS and Heart
 Kidney Antibodies  >289 publications with INS and Kidney
 Vascular Antibodies  >288 publications with INS and Vascular
 Nerve Antibodies  >288 publications with INS and Nerve
 Bone Antibodies  >168 publications with INS and Bone
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