NP_000596.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,550 Da
NCBI Official Full Name
interferon alpha-2
NCBI Official Synonym Full Names
interferon, alpha 2
NCBI Official Synonym Symbols
IFNA; INFA2; IFNA2B; IFN-alphaA [Similar Products]
NCBI Protein Information
interferon alpha-2
UniProt Protein Name
Interferon alpha-2
UniProt Synonym Protein Names
Interferon alpha-A; LeIF A
UniProt Synonym Gene Names
UniProt Entry Name
IFNA2_HUMAN
NCBI Summary for IFNa2
This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
UniProt Comments for IFNa2
IFNA2: Produced by macrophages, IFN-alpha have antiviral activities. Belongs to the alpha/beta interferon family.
Protein type: Membrane protein, integral; Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 9p22
Cellular Component: extracellular space; extracellular region
Molecular Function: protein binding; interferon-alpha/beta receptor binding; cytokine activity
Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; negative regulation of virion penetration into host cell; apoptosis; cytokine and chemokine mediated signaling pathway; innate immune response; inflammatory response; blood coagulation; negative regulation of transcription, DNA-dependent; negative regulation of T cell differentiation; defense response to virus; positive regulation of tyrosine phosphorylation of Stat3 protein
Research Articles on IFNa2
Precautions
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Disclaimer
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Products associated with IFNa2 elisa kit
Pathways associated with IFNa2 elisa kit
Diseases associated with IFNa2 elisa kit
Disease Name |
Pubmed Publications |
Skin Diseases Antibodies |
>2525 publications with IFNa2 and Skin Diseases |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Antibodies |
>1410 publications with IFNa2 and Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
Carcinoma, Renal Cell Antibodies |
>1401 publications with IFNa2 and Carcinoma, Renal Cell |
Anemia Antibodies |
>885 publications with IFNa2 and Anemia |
Fever Antibodies |
>789 publications with IFNa2 and Fever |
Lymphoma, Non-Hodgkin Antibodies |
>705 publications with IFNa2 and Lymphoma, Non-Hodgkin |
Neutropenia Antibodies |
>651 publications with IFNa2 and Neutropenia |
Fatigue Antibodies |
>645 publications with IFNa2 and Fatigue |
Mental Disorders Antibodies |
>633 publications with IFNa2 and Mental Disorders |
Thrombocytopenia Antibodies |
>610 publications with IFNa2 and Thrombocytopenia |
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