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IFN-beta1/IFNB elisa kit :: Human Interferon beta ELISA Kit

Scan QR to view Datasheet Catalog #    MBS280597 IFN-beta1/IFNB elisa kit
Unit / Price
48-Strip-Wells  /  $350 +1 FREE 8GB USB
96-Strip-Wells  /  $585 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,555 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,885 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interferon beta (IFN-beta1/IFNB), ELISA Kit

★Popular Item★
 Also Known As   

Human Interferon beta (IFN-beta1/IFNB) ELISA Kit

 Product Gene Name   

IFN-beta1/IFNB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    V00534 Genomic DNA
 3D Structure    ModBase 3D Structure for P01574
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human IFNB. No significant cross-reactivity or interference between Human IFNB and analogues was observed.
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 Preparation and Storage    Store at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IFN-beta1/IFNB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IFN-beta1/IFNB purchase    MBS280597 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interferon beta (IFN-beta1/IFNB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IFN-beta1/IFNB. The ELISA analytical biochemical technique of the MBS280597 kit is based on IFN-beta1/IFNB antibody-IFN-beta1/IFNB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IFN-beta1/IFNB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IFN-beta1/IFNB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IFN-beta1/IFNB elisa kit

   Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitative IFNB in Human serum, plasma. An antibody specific for IFNB has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IFNB present is bound by the immobilized antibody. After removing any unbound substances, a biotin - conjugated antibody specific for IFNB is added to the wells. After washing, Streptavidin conjugated Humanradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IFNB bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI/Uniprot data below describe general gene information for IFN-beta1/IFNB. It may not necessarily be applicable to this product.
 NCBI GI #    4504603
 NCBI GeneID    3456
 NCBI Accession #    NP_002167.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002176.3 [Other Products]
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 UniProt Primary Accession #    P01574 [Other Products]
 UniProt Secondary Accession #    Q5VWC9 [Other Products]
 UniProt Related Accession #    P01574 [Other Products]
 Molecular Weight    22,294 Da
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 NCBI Official Full Name    interferon beta
 NCBI Official Synonym Full Names    interferon beta 1
 NCBI Official Symbol    IFNB1 [Similar Products]
 NCBI Official Synonym Symbols   
IFB; IFF; IFNB; IFN-beta
[Similar Products]
 NCBI Protein Information    interferon beta
 UniProt Protein Name    Interferon beta
 UniProt Synonym Protein Names   
Fibroblast interferon
 Protein Family    Interferon
 UniProt Gene Name    IFNB1 [Similar Products]
 UniProt Synonym Gene Names    IFB; IFNB; IFN-beta [Similar Products]
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 NCBI Summary for IFN-beta1/IFNB    This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]
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 UniProt Comments for IFN-beta1/IFNB    IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p21.3

Cellular Component: extracellular region; extracellular space

Molecular Function: chloramphenicol O-acetyltransferase activity; cytokine activity; interferon-alpha/beta receptor binding

Biological Process: adaptive immune response; B cell activation involved in immune response; B cell differentiation; B cell proliferation; blood coagulation; cell surface receptor signaling pathway; defense response to bacterium; defense response to virus; humoral immune response; macrophage activation involved in immune response; natural killer cell activation; natural killer cell activation involved in immune response; negative regulation of T cell differentiation; negative regulation of viral genome replication; positive regulation of innate immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of transcription from RNA polymerase II promoter; regulation of MHC class I biosynthetic process; response to exogenous dsRNA; response to virus; T cell activation involved in immune response
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 Research Articles on IFN-beta1/IFNB    1. c-Cbl negatively regulates IFN-beta signaling and cellular antiviral response by promoting IRF3 ubiquitination and degradation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IFN-beta1/IFNB elisa kitPathways associated with IFN-beta1/IFNB elisa kit
 Reference Product  PubMed Publications
 IRF3 elisa kit  >12 publications with IFN-beta1/IFNB and IRF3
 IFNAR1 elisa kit  >4 publications with IFN-beta1/IFNB and IFNAR1
 IRF7 elisa kit  >3 publications with IFN-beta1/IFNB and IRF7
 STAT2 elisa kit  >2 publications with IFN-beta1/IFNB and STAT2
 IFNAR2 elisa kit  >1 publications with IFN-beta1/IFNB and IFNAR2
 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
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 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
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 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Diseases associated with IFN-beta1/IFNB elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >7 publications with IFN-beta1/IFNB and Neoplasms
 Carcinoma Antibodies  >4 publications with IFN-beta1/IFNB and Carcinoma
 Necrosis Antibodies  >4 publications with IFN-beta1/IFNB and Necrosis
 Inflammation Antibodies  >3 publications with IFN-beta1/IFNB and Inflammation
 Lung Neoplasms Antibodies  >2 publications with IFN-beta1/IFNB and Lung Neoplasms
 Multiple Sclerosis Antibodies  >2 publications with IFN-beta1/IFNB and Multiple Sclerosis
 Cardiovascular Diseases Antibodies  >2 publications with IFN-beta1/IFNB and Cardiovascular Diseases
 Melanoma Antibodies  >2 publications with IFN-beta1/IFNB and Melanoma
 Brain Diseases Antibodies  >2 publications with IFN-beta1/IFNB and Brain Diseases
 Neoplasm Metastasis Antibodies  >1 publications with IFN-beta1/IFNB and Neoplasm Metastasis
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