NP_002454.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
82,089 Da
NCBI Official Full Name
interferon-induced GTP-binding protein Mx2
NCBI Official Synonym Full Names
MX dynamin-like GTPase 2
NCBI Official Synonym Symbols
NCBI Protein Information
interferon-induced GTP-binding protein Mx2; p78-related protein; myxovirus resistance protein 2; second interferon-induced protein p78; myxovirus (influenza virus) resistance 2; interferon-regulated resistance GTP-binding protein MXB
UniProt Protein Name
Interferon-induced GTP-binding protein Mx2
UniProt Synonym Protein Names
Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
UniProt Entry Name
MX2_HUMAN
NCBI Summary for MX2
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]
UniProt Comments for MX2
MX2: has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]
Protein type: G protein regulator, misc.
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component: cytoplasm; nuclear pore; cytosol; nucleus
Molecular Function: GTPase activity; GTP binding
Biological Process: protein transport; mRNA transport; metabolic process; regulation of cell cycle; regulation of nucleocytoplasmic transport; response to virus; cytokine and chemokine mediated signaling pathway; defense response; defense response to virus
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Products associated with MX2 elisa kit
Pathways associated with MX2 elisa kit
Diseases associated with MX2 elisa kit
Organs/Tissues associated with MX2 elisa kit
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