Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow IFIT3 rightarrow Human IFIT3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Zinc finger protein 567 (ZNF567) Recombinant Protein
 • LCAT Antibody
 • CCNT2 siRNA
 • 40S ribosomal protein SA (RPSA) Recombinant Protein
 • Bifunctional UDP-N-acetylglucosamine 2-epimerase-N-acetylman... ELISA Kit
 • Kallikrein-1 (KLK1) Recombinant Protein
 • Heat Shock 70kDa Protein 1B (HSPA1B) ELISA Kit
 • Syntaxin 1A (STX1A) Protein
 • Probable proton ATPase 1A (H1A) Recombinant Protein
 • Norepinephrine Transporter (SLC6A2) Antibody
 • ADCY3 Antibody
 • Tryptophan 5-hydroxylase 1 (TPH1) ELISA Kit
 • BMP4 Antibody
 • Interferon Stimulated Gene 15 (ISG15) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

IFIT3 elisa kit :: Human Interferon-induced protein with tetratricopeptide repeats 3, IFIT3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602757
Typical Testing Data/Standard Curve
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $420 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interferon-induced protein with tetratricopeptide repeats 3, IFIT3, ELISA Kit

 Also Known As   

Human Interferon-induced protein with tetratricopeptide repeats 3, IFIT3 ELISA Kit

 Product Gene Name   

IFIT3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    604650
 3D Structure    ModBase 3D Structure for O14879
Section Bar
 Species Reactivity    Human
Section Bar
 Specificity    No cross-reaction with other factors.
Section Bar
 Samples    Human serum, plasma or cell culture supernatant and organizations in the natural and recombinant IFIT3 concentration.
 Assay Type    Sandwich
 Detection Range    20 ng/ml-0.312 ng/ml
 Sensitivity    0.06 ng/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of IFIT3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IFIT3 purchase    MBS2602757 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interferon-induced protein with tetratricopeptide repeats 3, IFIT3, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 20 ng/ml-0.312 ng/ml in biological research samples containing IFIT3, with an estimated sensitivity of 0.06 ng/ml. The ELISA analytical biochemical technique of the MBS2602757 kit is based on IFIT3 antibody-IFIT3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IFIT3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IFIT3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Human serum, plasma or cell culture supernatant and organizations in the natural and recombinant IFIT3 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Product Description specifically for IFIT3 elisa kit

   Principle of the Assay||This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human IFIT3 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
Section Bar
 Typical Testing Data/Standard Curve of IFIT3 elisa kit    IFIT3 elisa kit Typical Testing Data/Standard Curve image
Table BarTOPTable Bar
Sample Manual Insert of MBS2602757
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for IFIT3. It may not necessarily be applicable to this product.
 NCBI GI #    72534658
 NCBI GeneID    3437
 NCBI Accession #    NP_001026853.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001031683.3 [Other Products]
Section Bar
 UniProt Primary Accession #    O14879 [Other Products]
 UniProt Secondary Accession #    Q99634; Q9BSK7 [Other Products]
 UniProt Related Accession #    O14879 [Other Products]
 Molecular Weight    55,985 Da
Table BarTOPTable Bar
 NCBI Official Full Name    interferon-induced protein with tetratricopeptide repeats 3 isoform a
 NCBI Official Synonym Full Names    interferon-induced protein with tetratricopeptide repeats 3
 NCBI Official Symbol    IFIT3 [Similar Products]
 NCBI Official Synonym Symbols   
P60; IRG2; IFI60; IFIT4; ISG60; RIG-G; CIG-49; GARG-49
[Similar Products]
 NCBI Protein Information    interferon-induced protein with tetratricopeptide repeats 3; CIG49; IFIT-3; IFIT-4; ISG-60; IFI-60K; interferon-induced 60 kDa protein; retinoic acid-induced gene G protein; interferon-induced protein with tetratricopeptide repeats 4
 UniProt Protein Name    Interferon-induced protein with tetratricopeptide repeats 3
 UniProt Synonym Protein Names   
CIG49; ISG-60; Interferon-induced 60 kDa protein; IFI-60K; Interferon-induced protein with tetratricopeptide repeats 4; IFIT-4; Retinoic acid-induced gene G protein; P60; RIG-G
 Protein Family    Interferon-induced protein with tetratricopeptide repeats
 UniProt Gene Name    IFIT3 [Similar Products]
 UniProt Synonym Gene Names    CIG-49; IFI60; IFIT4; ISG60; IFIT-3; IFI-60K; IFIT-4; P60; RIG-G [Similar Products]
 UniProt Entry Name    IFIT3_HUMAN
Section Bar
 UniProt Comments for IFIT3    IFIT3: IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS- mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exihibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27. Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin- dependent degradation. IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels. Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21. Can negatively regulate the apoptotic effects of IFIT2. Belongs to the IFIT family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: mitochondrion; cytoplasm; cytosol

Molecular Function: identical protein binding; protein binding

Biological Process: negative regulation of cell proliferation; response to virus; cytokine and chemokine mediated signaling pathway; defense response to virus; negative regulation of apoptosis
Table BarTOPTable Bar
 Research Articles on IFIT3    1. protective roles of IFIT3 following IFN-alpha production in DV infection of human lung epithelial cells
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with IFIT3 elisa kitPathways associated with IFIT3 elisa kit
 Reference Product  PubMed Publications
 IFIT1 elisa kit  >13 publications with IFIT3 and IFIT1
 IFIT2 elisa kit  >11 publications with IFIT3 and IFIT2
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
Diseases associated with IFIT3 elisa kitOrgans/Tissues associated with IFIT3 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >9 publications with IFIT3 and Neoplasms
 Leukemia, Promyelocytic, Acute Antibodies  >6 publications with IFIT3 and Leukemia, Promyelocytic, Acute
 Inflammation Antibodies  >3 publications with IFIT3 and Inflammation
 Liver Diseases Antibodies  >2 publications with IFIT3 and Liver Diseases
 Fever Antibodies  >1 publications with IFIT3 and Fever
 Carcinoma Antibodies  >1 publications with IFIT3 and Carcinoma
 Melanoma Antibodies  >1 publications with IFIT3 and Melanoma
 Neoplasms, Experimental Antibodies  >1 publications with IFIT3 and Neoplasms, Experimental
 Necrosis Antibodies  >1 publications with IFIT3 and Necrosis
 Carcinoma, Hepatocellular Antibodies  >1 publications with IFIT3 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with IFIT3 and Blood
 Brain Antibodies  >6 publications with IFIT3 and Brain
 Kidney Antibodies  >2 publications with IFIT3 and Kidney
 Liver Antibodies  >2 publications with IFIT3 and Liver
 Lymph Node Antibodies  >1 publications with IFIT3 and Lymph Node
 Bone Marrow Antibodies  >1 publications with IFIT3 and Bone Marrow
 Mouth Antibodies  >1 publications with IFIT3 and Mouth
 Muscle Antibodies  >1 publications with IFIT3 and Muscle
 Lung Antibodies  >1 publications with IFIT3 and Lung
 Vascular Antibodies  >1 publications with IFIT3 and Vascular
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions