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IFITM3 elisa kit :: Human Interferon-induced transmembrane protein 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS763456
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $280 +1 FREE 8GB USB
96-Strip-Wells  /  $375 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,015 +3 FREE 8GB USB
15x96-Strip-Wells  /  $4,285 +5 FREE 8GB USB
25x96-Strip-Wells  /  $6,715 +8 FREE 8GB USB
 
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 Product Name   

Interferon-induced transmembrane protein 3 (IFITM3), ELISA Kit

★Popular Item★
 Also Known As   

Human Interferon-induced transmembrane protein 3 ELISA Kit

 Product Synonym Names    IFITM3/Fragilis/IP15/mil-1/1-8U/DSPA2b/interferon induced transmembrane protein 3/interferon-induced transmembrane protein 3/Interferon-inducible protein 1-8U
 Product Gene Name   

IFITM3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS763456 COA    COA PDF
 OMIM    605579
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of IFITM3. No significant cross-reactivity or interference between IFITM3 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    31.2-2000pg/ml
 Sensitivity    <18.75pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level IFITM3 were tested 20 times on one plate, respectively. Intra-Assay: CV<8%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level IFITM3 were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%
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 Preparation and Storage    Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IFITM3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IFITM3 purchase    MBS763456 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interferon-induced transmembrane protein 3 (IFITM3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2-2000pg/ml in biological research samples containing IFITM3, with an estimated sensitivity of <18.75pg/ml. The ELISA analytical biochemical technique of the MBS763456 kit is based on IFITM3 antibody-IFITM3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IFITM3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IFITM3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IFITM3 elisa kit

   Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti- IFITM3 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti- IFITM3 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and washed with wash buffer. HRPStreptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the IFITM3 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of IFITM3 can be calculated.
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 Typical Standard Curve/Testing Data of IFITM3 elisa kit    IFITM3 elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS763456. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IFITM3. It may not necessarily be applicable to this product.
 NCBI GI #    148612842
 NCBI GeneID    10410
 NCBI Accession #    NP_066362.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021034.2 [Other Products]
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 UniProt Secondary Accession #    Q53Y76; Q96HK8; Q96J15 [Other Products]
 UniProt Related Accession #    Q01628 [Other Products]
 Molecular Weight    14,632 Da
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 NCBI Official Full Name    interferon-induced transmembrane protein 3
 NCBI Official Synonym Full Names    interferon induced transmembrane protein 3
 NCBI Official Symbol    IFITM3 [Similar Products]
 NCBI Official Synonym Symbols   
1-8U; IP15; DSPA2b
[Similar Products]
 NCBI Protein Information    interferon-induced transmembrane protein 3
 UniProt Protein Name    Interferon-induced transmembrane protein 3
 UniProt Synonym Protein Names   
Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U
 Protein Family    Interferon-induced transmembrane protein
 UniProt Gene Name    IFITM3 [Similar Products]
 UniProt Synonym Gene Names    DSPA2b [Similar Products]
 UniProt Entry Name    IFM3_HUMAN
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 NCBI Summary for IFITM3    The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012]
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 UniProt Comments for IFITM3    IFITM3: IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Interacts with SPP1; the interaction reduces OPN expression. By IFN-alpha and IFNG/IFN-gamma. Belongs to the CD225/Dispanin family.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: integral to membrane; late endosome membrane; lysosomal membrane; plasma membrane

Molecular Function: protein binding

Biological Process: cytokine and chemokine mediated signaling pathway; defense response to virus; immune response; negative regulation of viral genome replication; negative regulation of viral transcription; negative regulation of virion penetration into host cell; response to virus

Disease: Influenza, Severe, Susceptibility To
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 Research Articles on IFITM3    1. Our meta-analysis suggests a significant association between a minor IFITM3 allele (SNP rs12252-C) with severe influenza susceptibility, but not in mild influenza subjects
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IFITM3 elisa kitPathways associated with IFITM3 elisa kit
 Reference Product  PubMed Publications
 ISG15 elisa kit  >5 publications with IFITM3 and ISG15
 MX1 elisa kit  >5 publications with IFITM3 and MX1
 IFIT1 elisa kit  >3 publications with IFITM3 and IFIT1
 IFI6 elisa kit  >3 publications with IFITM3 and IFI6
 ISG20 elisa kit  >2 publications with IFITM3 and ISG20
 OAS1 elisa kit  >2 publications with IFITM3 and OAS1
 IFI27 elisa kit  >2 publications with IFITM3 and IFI27
 IFIT3 elisa kit  >2 publications with IFITM3 and IFIT3
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
Diseases associated with IFITM3 elisa kitOrgans/Tissues associated with IFITM3 elisa kit
 Disease Name  Pubmed Publications
 Influenza, Human Antibodies  >44 publications with IFITM3 and Influenza, Human
 Inflammation Antibodies  >10 publications with IFITM3 and Inflammation
 Lung Diseases Antibodies  >9 publications with IFITM3 and Lung Diseases
 Adenocarcinoma Antibodies  >5 publications with IFITM3 and Adenocarcinoma
 Disease Models, Animal Antibodies  >4 publications with IFITM3 and Disease Models, Animal
 Brain Diseases Antibodies  >4 publications with IFITM3 and Brain Diseases
 Necrosis Antibodies  >4 publications with IFITM3 and Necrosis
 Breast Neoplasms Antibodies  >3 publications with IFITM3 and Breast Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with IFITM3 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >2 publications with IFITM3 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >18 publications with IFITM3 and Lung
 Blood Antibodies  >13 publications with IFITM3 and Blood
 Brain Antibodies  >11 publications with IFITM3 and Brain
 Ovary Antibodies  >5 publications with IFITM3 and Ovary
 Embryonic Tissue Antibodies  >5 publications with IFITM3 and Embryonic Tissue
 Liver Antibodies  >5 publications with IFITM3 and Liver
 Kidney Antibodies  >5 publications with IFITM3 and Kidney
 Heart Antibodies  >4 publications with IFITM3 and Heart
 Intestine Antibodies  >4 publications with IFITM3 and Intestine
 Spleen Antibodies  >4 publications with IFITM3 and Spleen
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