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IL15RA elisa kit :: Human Interleukin-15 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS284419 IL15RA elisa kit
Unit / Price
48-Strip-Wells  /  $425 +1 FREE 8GB USB
96-Strip-Wells  /  $720 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,160 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,055 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin-15 (IL15RA), ELISA Kit

★Popular Item★
 Also Known As   

Human Interleukin-15 receptor subunit alpha (IL15RA) ELISA Kit

 Product Synonym Names    RP11-536K7.2; MGC104179;
 Product Gene Name   

IL15RA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    U31628 mRNA
 3D Structure    ModBase 3D Structure for Q13261
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human IL15RA. No significant cross-reactivity or interference between Human IL15RA and analogues was observed.
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 Samples    Serum, Plasma, Other biological fluids
 Assay Type    Sandwich
 Sample Volume    1-200 uL
 Precision    Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
 Detection Wavelength    450 nm
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 Preparation and Storage    Store at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL15RA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL15RA purchase    MBS284419 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin-15 (IL15RA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL15RA. The ELISA analytical biochemical technique of the MBS284419 kit is based on IL15RA antibody-IL15RA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL15RA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL15RA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL15RA elisa kit

   Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate IL15RA in samples. An antibody specific for IL15RA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyIL15RA present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL15RA is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL15RA bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI/Uniprot data below describe general gene information for IL15RA. It may not necessarily be applicable to this product.
 NCBI GI #    343780891
 NCBI GeneID    3601
 NCBI Accession #    NP_001230468.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243539.1 [Other Products]
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 UniProt Primary Accession #    Q13261 [Other Products]
 UniProt Secondary Accession #    Q3B769; Q5JVA1; Q5JVA2; Q5JVA4; Q6B0J2; Q7LDR4; Q7Z609; B4E2C2 [Other Products]
 UniProt Related Accession #    Q13261 [Other Products]
 Molecular Weight    24,388 Da
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 NCBI Official Full Name    interleukin-15 receptor subunit alpha isoform 3
 NCBI Official Synonym Full Names    interleukin 15 receptor subunit alpha
 NCBI Official Symbol    IL15RA [Similar Products]
 NCBI Official Synonym Symbols   
CD215
[Similar Products]
 NCBI Protein Information    interleukin-15 receptor subunit alpha
 UniProt Protein Name    Interleukin-15 receptor subunit alpha
 UniProt Synonym Protein Names   
CD_antigen: CD215
 Protein Family    Interleukin
 UniProt Gene Name    IL15RA [Similar Products]
 UniProt Synonym Gene Names    IL-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; sIL-15 receptor subunit alpha; sIL-15R-alpha; sIL-15RA [Similar Products]
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 NCBI Summary for IL15RA    This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]
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 UniProt Comments for IL15RA    IL15RA: High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves STAT3, STAT5, STAT6, JAK2 and SYK. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: cytoplasmic vesicle membrane; endoplasmic reticulum membrane; extracellular space; Golgi membrane; integral component of membrane; nuclear membrane; plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; signal transducer activity

Biological Process: cell proliferation; cytokine-mediated signaling pathway; signal transduction
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 Research Articles on IL15RA    1. this work provides evidence that the sushi-IL-15Ralpha/IL-15 fusion protein RLI enhances antitumor activity of anti-PD-1 treatment and is a promising approach to stimulate host immunity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL15RA elisa kitPathways associated with IL15RA elisa kit
 Reference Product  PubMed Publications
 IL15 elisa kit  >224 publications with IL15RA and IL15
 IL2RB elisa kit  >22 publications with IL15RA and IL2RB
 IL2RG elisa kit  >11 publications with IL15RA and IL2RG
 TRAF2 elisa kit  >4 publications with IL15RA and TRAF2
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 TCR Signaling Pathway antibodies  TCR Signaling Pathway Diagram
Diseases associated with IL15RA elisa kitOrgans/Tissues associated with IL15RA elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >25 publications with IL15RA and Necrosis
 Inflammation Antibodies  >19 publications with IL15RA and Inflammation
 Lymphoma Antibodies  >12 publications with IL15RA and Lymphoma
 Prostatic Diseases Antibodies  >3 publications with IL15RA and Prostatic Diseases
 Vascular Diseases Antibodies  >3 publications with IL15RA and Vascular Diseases
 Lung Neoplasms Antibodies  >3 publications with IL15RA and Lung Neoplasms
 Hyperplasia Antibodies  >3 publications with IL15RA and Hyperplasia
 Hypertrophy Antibodies  >2 publications with IL15RA and Hypertrophy
 Liver Diseases Antibodies  >2 publications with IL15RA and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with IL15RA and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >162 publications with IL15RA and Blood
 Spleen Antibodies  >18 publications with IL15RA and Spleen
 Lung Antibodies  >11 publications with IL15RA and Lung
 Intestine Antibodies  >10 publications with IL15RA and Intestine
 Skin Antibodies  >8 publications with IL15RA and Skin
 Liver Antibodies  >6 publications with IL15RA and Liver
 Brain Antibodies  >5 publications with IL15RA and Brain
 Uterus Antibodies  >5 publications with IL15RA and Uterus
 Eye Antibodies  >3 publications with IL15RA and Eye
 Prostate Antibodies  >3 publications with IL15RA and Prostate
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