NP_001269328.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
62,304 Da
NCBI Official Full Name
interleukin-18 receptor 1 isoform 2
NCBI Official Synonym Full Names
interleukin 18 receptor 1
NCBI Official Synonym Symbols
CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp [Similar Products]
NCBI Protein Information
interleukin-18 receptor 1
UniProt Protein Name
Interleukin-18 receptor 1
UniProt Synonym Protein Names
CD218 antigen-like family member A; CDw218a; IL1 receptor-related protein; IL-1Rrp; IL1R-rp; CD_antigen: CD218a
UniProt Synonym Gene Names
NCBI Summary for IL18R1
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
UniProt Comments for IL18R1
Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B (Probable) (PubMed:8626725). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 ().
Research Articles on IL18R1
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Products associated with IL18R1 elisa kit
Pathways associated with IL18R1 elisa kit
Diseases associated with IL18R1 elisa kit
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