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IL-1alpha elisa kit :: Human Interleukin 1alpha, IL-1alpha ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9301493 IL-1alpha elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 1alpha, IL-1alpha, ELISA Kit

 Also Known As   

Human Interleukin 1alpha, IL-1alpha ELISA Kit

 Product Synonym Names    Human Interleukin 1a, IL-1a ELISA Kit
 Product Gene Name   

IL-1alpha elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 Chromosome Location    Chromosome: 2; NC_000002.11 (113531492..113542971, complement). Location: 2q14
 OMIM    147760
 3D Structure    ModBase 3D Structure for P01583
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Serum, Plasma and Tissue Homogenate
 Assay Type    Sandwich
 Detection Range    6.25 pg/ml - 200 pg/ml.
 Sensitivity    1.0 pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of IL-1alpha elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL-1alpha purchase    MBS9301493 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 1alpha, IL-1alpha, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 6.25 pg/ml - 200 pg/ml in biological research samples containing IL-1alpha, with an estimated sensitivity of 1.0 pg/ml. The ELISA analytical biochemical technique of the MBS9301493 kit is based on IL-1alpha antibody-IL-1alpha antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-1alpha antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-1alpha. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma and Tissue Homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for IL-1alpha elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IL1A (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS9301493
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NCBI/Uniprot data below describe general gene information for IL-1alpha. It may not necessarily be applicable to this product.
 NCBI GI #    27894330
 NCBI GeneID    3552
 NCBI Accession #    NP_000566.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_000575.3 [Other Products]
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 UniProt Primary Accession #    P01583 [Other Products]
 UniProt Secondary Accession #    Q53QF9; Q7RU02 [Other Products]
 UniProt Related Accession #    P01583 [Other Products]
 Molecular Weight    30,607 Da
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 NCBI Official Full Name    interleukin-1 alpha proprotein
 NCBI Official Synonym Full Names    interleukin 1, alpha
 NCBI Official Symbol    IL1A [Similar Products]
 NCBI Official Synonym Symbols   
IL1; IL-1A; IL1F1; IL1-ALPHA
[Similar Products]
 NCBI Protein Information    interleukin-1 alpha; IL-1 alpha; hematopoietin-1; preinterleukin 1 alpha; pro-interleukin-1-alpha
 UniProt Protein Name    Interleukin-1 alpha
 UniProt Synonym Protein Names   
Hematopoietin-1
 UniProt Gene Name    IL1A [Similar Products]
 UniProt Synonym Gene Names    IL1F1; IL-1 alpha [Similar Products]
 UniProt Entry Name    IL1A_HUMAN
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 NCBI Summary for IL-1alpha    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL-1alpha    IL1A: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Belongs to the IL-1 family.

Protein type: Cytokine; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q14

Cellular Component: extracellular space; extracellular region; cytosol

Molecular Function: protein binding; copper ion binding; interleukin-1 receptor binding; cytokine activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of mitosis; apoptosis; positive regulation of interleukin-2 biosynthetic process; cytokine and chemokine mediated signaling pathway; germ cell programmed cell death; positive regulation of JNK cascade; fever; negative regulation of cell proliferation; cell proliferation; connective tissue replacement during inflammatory response; positive regulation of angiogenesis; response to copper ion; positive regulation of transcription from RNA polymerase II promoter; immune response; inflammatory response; positive regulation of cytokine secretion
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 Research Articles on IL-1alpha    1. This meta-analysis/review suggests that IL-1A is a candidate gene for Alzheimer's disease susceptibility.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL-1alpha elisa kitPathways associated with IL-1alpha elisa kit
 Reference Product  PubMed Publications
 IL1B elisa kit  >157 publications with IL-1alpha and IL1B
 IL6 elisa kit  >75 publications with IL-1alpha and IL6
 IL8 elisa kit  >26 publications with IL-1alpha and IL8
 IL1R1 elisa kit  >13 publications with IL-1alpha and IL1R1
 CSF2 elisa kit  >7 publications with IL-1alpha and CSF2
 MYD88 elisa kit  >3 publications with IL-1alpha and MYD88
 IL1R2 elisa kit  >3 publications with IL-1alpha and IL1R2
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 FAS Pathway And Stress Induction Of HSP Regulation antibodies  FAS Pathway And Stress Induction Of HSP Regulation Diagram
 Graft-versus-host Disease Pathway antibodies  Graft-versus-host Disease Pathway Diagram
 Graft-versus-host Disease Pathway antibodies  Graft-versus-host Disease Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
Diseases associated with IL-1alpha elisa kitOrgans/Tissues associated with IL-1alpha elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >59 publications with IL-1alpha and Inflammation
 Necrosis Antibodies  >44 publications with IL-1alpha and Necrosis
 Neoplasms Antibodies  >38 publications with IL-1alpha and Neoplasms
 Skin Diseases Antibodies  >27 publications with IL-1alpha and Skin Diseases
 Cardiovascular Diseases Antibodies  >20 publications with IL-1alpha and Cardiovascular Diseases
 Lung Diseases Antibodies  >15 publications with IL-1alpha and Lung Diseases
 Kidney Diseases Antibodies  >8 publications with IL-1alpha and Kidney Diseases
 Heart Diseases Antibodies  >6 publications with IL-1alpha and Heart Diseases
 Drug Toxicity Antibodies  >6 publications with IL-1alpha and Drug Toxicity
 Pain Antibodies  >5 publications with IL-1alpha and Pain
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >18 publications with IL-1alpha and Skin
 Lung Antibodies  >13 publications with IL-1alpha and Lung
 Vascular Antibodies  >11 publications with IL-1alpha and Vascular
 Brain Antibodies  >10 publications with IL-1alpha and Brain
 Testis Antibodies  >4 publications with IL-1alpha and Testis
 Mouth Antibodies  >3 publications with IL-1alpha and Mouth
 Cervix Antibodies  >2 publications with IL-1alpha and Cervix
 Lymph Node Antibodies  >2 publications with IL-1alpha and Lymph Node
 Intestine Antibodies  >1 publications with IL-1alpha and Intestine
 Pharynx Antibodies  >1 publications with IL-1alpha and Pharynx
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