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IL-23 elisa kit :: Human Interleukin 23 (IL-23) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS265395
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $420 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin 23 (IL-23), ELISA Kit

 Also Known As   

Human Interleukin 23 (IL-23) ELISA Kit

 Product Gene Name   

IL-23 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    605510
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 Species Reactivity    Human
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 Specificity    No cross-reaction with other factors.
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 Samples    Serum, plasma or cell culture supernatant and organizations in the natural and recombinant IL-23 concentration.
 Assay Type    Sandwich
 Detection Range    1000 pg/ml-15.6 pg/ml
 Sensitivity    5 pg/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of IL-23 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL-23 purchase    MBS265395 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 23 (IL-23) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1000 pg/ml-15.6 pg/ml in biological research samples containing IL-23, with an estimated sensitivity of 5 pg/ml. The ELISA analytical biochemical technique of the MBS265395 kit is based on IL-23 antibody-IL-23 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-23 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-23. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma or cell culture supernatant and organizations in the natural and recombinant IL-23 concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for IL-23 elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human IL-23 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of IL-23 elisa kit    IL-23 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS265395
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NCBI/Uniprot data below describe general gene information for IL-23. It may not necessarily be applicable to this product.
 NCBI GI #    27894302
 NCBI GeneID    27178
 NCBI Accession #    NP_775297.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_173205.1 [Other Products]
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 UniProt Secondary Accession #    Q56AP9; Q8TD04; Q8TD05; Q9HBF2; Q9HBF3; Q9UHA6; B5BU97 [Other Products]
 UniProt Related Accession #    Q9NZH6 [Other Products]
 Molecular Weight    17,459 Da
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 NCBI Official Full Name    interleukin-37 isoform 5
 NCBI Official Synonym Full Names    interleukin 37
 NCBI Official Symbol    IL37 [Similar Products]
 NCBI Official Synonym Symbols   
FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)
[Similar Products]
 NCBI Protein Information    interleukin-37; FIL1 zeta; IL-1 zeta; IL-1X protein; interleukin-23; interleukin 1, zeta; interleukin-1 homolog 4; interleukin-1 superfamily z; interleukin 1 family member 7; interleukin-1-related protein; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL1F7 (canonical product IL-1F7b)
 UniProt Protein Name    Interleukin-37
 UniProt Synonym Protein Names   
FIL1 zeta; IL-1X; Interleukin-1 family member 7; IL-1F7; Interleukin-1 homolog 4; IL-1H; IL-1H4; Interleukin-1 zeta; IL-1 zeta; Interleukin-1-related protein; IL-1RP1; Interleukin-23; IL-37
 UniProt Gene Name    IL37 [Similar Products]
 UniProt Synonym Gene Names    FIL1Z; IL1F7; IL1H4; IL1RP1; IL-1F7; IL-1H; IL-1H4; IL-1 zeta; IL-1RP1; IL-37 [Similar Products]
 UniProt Entry Name    IL37_HUMAN
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 NCBI Summary for IL-23    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL-23    IL37: Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation. Belongs to the IL-1 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 2q12-q14.1

Cellular Component: nucleoplasm; extracellular space; cytoplasm; nucleolus; extracellular region; cytosol; nucleus

Molecular Function: interleukin-1 receptor binding; cytokine activity

Biological Process: cytokine and chemokine mediated signaling pathway; immune response; inflammatory response
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 Research Articles on IL-23    1. IL-37 associated with SLE disease activity, especially related with systemic Lupus erythematosus renal disease activity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL-23 elisa kitDiseases associated with IL-23 elisa kit
 Reference Product  PubMed Publications
 CASP1 elisa kit  >1 publications with IL-23 and CASP1
 SMAD3 elisa kit  >1 publications with IL-23 and SMAD3
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >13 publications with IL-23 and Inflammation
 Disease Models, Animal Antibodies  >4 publications with IL-23 and Disease Models, Animal
 Necrosis Antibodies  >4 publications with IL-23 and Necrosis
 Liver Diseases Antibodies  >3 publications with IL-23 and Liver Diseases
 Death Antibodies  >1 publications with IL-23 and Death
 Heart Diseases Antibodies  >1 publications with IL-23 and Heart Diseases
 Weight Loss Antibodies  >1 publications with IL-23 and Weight Loss
 Drug-Induced Liver Injury Antibodies  >1 publications with IL-23 and Drug-Induced Liver Injury
Organs/Tissues associated with IL-23 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >1 publications with IL-23 and Intestine
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