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IRAK elisa kit :: Human Interleukin Receptor Associated Kinase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS017014 IRAK elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interleukin Receptor Associated Kinase (IRAK), ELISA Kit

 Also Known As   

Human Interleukin Receptor Associated Kinase ELISA Kit

 Product Gene Name   

IRAK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605457
 3D Structure    ModBase 3D Structure for Q8N6P7
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 Species Reactivity    Human
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IRAK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IRAK purchase    MBS017014 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin Receptor Associated Kinase (IRAK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IRAK. The ELISA analytical biochemical technique of the MBS017014 kit is based on IRAK antibody-IRAK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IRAK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IRAK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IRAK. It may not necessarily be applicable to this product.
 NCBI GI #    31317239
 NCBI GeneID    58985
 NCBI Accession #    NP_067081.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021258.3 [Other Products]
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 UniProt Primary Accession #    Q8N6P7 [Other Products]
 UniProt Secondary Accession #    Q9HB22; A8K839; B2R9Y9 [Other Products]
 UniProt Related Accession #    Q8N6P7 [Other Products]
 Molecular Weight    63,077 Da
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 NCBI Official Full Name    interleukin-22 receptor subunit alpha-1
 NCBI Official Synonym Full Names    interleukin 22 receptor, alpha 1
 NCBI Official Symbol    IL22RA1 [Similar Products]
 NCBI Official Synonym Symbols   
IL22R; CRF2-9; IL22R1
[Similar Products]
 NCBI Protein Information    interleukin-22 receptor subunit alpha-1; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9
 UniProt Protein Name    Interleukin-22 receptor subunit alpha-1
 UniProt Synonym Protein Names   
Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9; ZcytoR11
 UniProt Gene Name    IL22RA1 [Similar Products]
 UniProt Synonym Gene Names    IL22R; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1; CRF2-9 [Similar Products]
 UniProt Entry Name    I22R1_HUMAN
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 NCBI Summary for IRAK    The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IRAK    IL22RA1: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. Belongs to the type II cytokine receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: plasma membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interferon receptor activity; interleukin-20 binding

Biological Process: cytokine and chemokine mediated signaling pathway; defense response to Gram-negative bacterium
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 Research Articles on IRAK    1. the CC genotype of rs3795299 polymorphism in the IL-22R1 gene is associated with the reduced risk of IgAN, and this genetic association was supported by the higher renal expression of IL-22R1 in healthy controls compared with patients with IgAN.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IRAK elisa kitPathways associated with IRAK elisa kit
 Reference Product  PubMed Publications
 IL22 elisa kit  >4 publications with IRAK and IL22
 IL20 elisa kit  >2 publications with IRAK and IL20
 IL24 elisa kit  >2 publications with IRAK and IL24
 IL10RB elisa kit  >2 publications with IRAK and IL10RB
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with IRAK elisa kitOrgans/Tissues associated with IRAK elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with IRAK and Neoplasms
 Disease Models, Animal Antibodies  >1 publications with IRAK and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >1 publications with IRAK and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >1 publications with IRAK and Breast Neoplasms
 Immune System Diseases Antibodies  >1 publications with IRAK and Immune System Diseases
 Inflammation Antibodies  >1 publications with IRAK and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with IRAK and Skin
 Thyroid Antibodies  >1 publications with IRAK and Thyroid
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