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ITSN2 elisa kit :: Human Intersectin 2 (ITSN2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9311781 ITSN2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Intersectin 2 (ITSN2), ELISA Kit

 Also Known As   

Human Intersectin 2 (ITSN2) ELISA Kit

 Product Gene Name   

ITSN2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 2; NC_000002.11 (24425735..24583397, complement). Location: 2pter-p25.1
 OMIM    604464
 3D Structure    ModBase 3D Structure for Q9NZM3
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ITSN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ITSN2 purchase    MBS9311781 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Intersectin 2 (ITSN2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITSN2. The ELISA analytical biochemical technique of the MBS9311781 kit is based on ITSN2 antibody-ITSN2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITSN2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITSN2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ITSN2. It may not necessarily be applicable to this product.
 NCBI GI #    194294525
 NCBI GeneID    50618
 NCBI Accession #    NP_671494.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_147152.2 [Other Products]
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 UniProt Primary Accession #    Q9NZM3 [Other Products]
 UniProt Secondary Accession #    O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9ULG4 [Other Products]
 UniProt Related Accession #    Q9NZM3 [Other Products]
 Molecular Weight    193,461 Da
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 NCBI Official Full Name    intersectin-2 isoform 2
 NCBI Official Synonym Full Names    intersectin 2
 NCBI Official Symbol    ITSN2 [Similar Products]
 NCBI Official Synonym Symbols   
SWA; SWAP; SH3D1B; SH3P18; PRO2015
[Similar Products]
 NCBI Protein Information    intersectin-2; SH3 domain-containing protein 1B; SH3P18-like WASP-associated protein
 UniProt Protein Name    Intersectin-2
 UniProt Synonym Protein Names   
SH3 domain-containing protein 1B; SH3P18; SH3P18-like WASP-associated protein
 Protein Family    Intersectin
 UniProt Gene Name    ITSN2 [Similar Products]
 UniProt Synonym Gene Names    KIAA1256; SH3D1B; SWAP [Similar Products]
 UniProt Entry Name    ITSN2_HUMAN
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 NCBI Summary for ITSN2    This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ITSN2    ITSN2: adapter protein that contains SH3 domains. Involved in the formation of clathrin-coated vesicles. May function in the induction of T cell antigen receptor (TCR) endocytosis. May provide indirect link between the endocytic membrane traffic and the actin assembly machinery. Three alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cytoplasm

Molecular Function: Rho guanyl-nucleotide exchange factor activity; protein binding; SH3/SH2 adaptor activity; calcium ion binding

Biological Process: positive regulation of signal transduction; endocytosis
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 Research Articles on ITSN2    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ITSN2 elisa kitPathways associated with ITSN2 elisa kit
 Reference Product  PubMed Publications
 CDC42 elisa kit  >5 publications with ITSN2 and CDC42
 EPS8 elisa kit  >1 publications with ITSN2 and EPS8
 NUMB elisa kit  >1 publications with ITSN2 and NUMB
 Products by Pathway  Pathway Diagram
 Regulation Of CDC42 Activity Pathway antibodies  Regulation Of CDC42 Activity Pathway Diagram
Diseases associated with ITSN2 elisa kitOrgans/Tissues associated with ITSN2 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with ITSN2 and Neoplasms
 Nervous System Diseases Antibodies  >3 publications with ITSN2 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with ITSN2 and Brain Diseases
 Memory Disorders Antibodies  >1 publications with ITSN2 and Memory Disorders
 Learning Disorders Antibodies  >1 publications with ITSN2 and Learning Disorders
 Cognition Disorders Antibodies  >1 publications with ITSN2 and Cognition Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with ITSN2 and Brain
 Blood Antibodies  >2 publications with ITSN2 and Blood
 Nerve Antibodies  >2 publications with ITSN2 and Nerve
 Kidney Antibodies  >1 publications with ITSN2 and Kidney
 Lung Antibodies  >1 publications with ITSN2 and Lung
 Skin Antibodies  >1 publications with ITSN2 and Skin
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