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iNV elisa kit :: Human Involucrin (iNV) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS269878
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $260 +1 FREE 8GB USB
96-Strip-Wells  /  $405 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Involucrin (iNV), ELISA Kit

★Popular Item★
 Also Known As   

Human Involucrin (iNV) ELISA Kit

 Product Gene Name   

iNV elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    147360
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 Species Reactivity    Human
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 Specificity    No cross-reaction with other factors.
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 Samples    Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant iNV concentration
 Assay Type    Sandwich
 Detection Range    20 ng/ml-0.312 ng/ml
 Sensitivity    0.06 ng/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of iNV elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for iNV purchase    MBS269878 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Involucrin (iNV) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 20 ng/ml-0.312 ng/ml in biological research samples containing iNV, with an estimated sensitivity of 0.06 ng/ml. The ELISA analytical biochemical technique of the MBS269878 kit is based on iNV antibody-iNV antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect iNV antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, iNV. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant iNV concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for iNV elisa kit

   Principle of the assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human iNV monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of iNV elisa kit    iNV elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS269878. Click to request current manual
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NCBI/Uniprot data below describe general gene information for iNV. It may not necessarily be applicable to this product.
 NCBI GI #    44890059
 NCBI GeneID    3713
 NCBI Accession #    NP_005538.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005547.2 [Other Products]
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 UniProt Secondary Accession #    Q5T7P4 [Other Products]
 UniProt Related Accession #    P07476 [Other Products]
 Molecular Weight    68,479 Da
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 NCBI Official Full Name    involucrin
 NCBI Official Synonym Full Names    involucrin
 NCBI Official Symbol    IVL [Similar Products]
 NCBI Protein Information    involucrin
 UniProt Protein Name    Involucrin
 Protein Family    Homeobox protein
 UniProt Gene Name    IVL [Similar Products]
 UniProt Entry Name    INVO_HUMAN
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 NCBI Summary for iNV    Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]
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 UniProt Comments for iNV    IVL: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. Belongs to the involucrin family.

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cornified envelope

Molecular Function: protein binding, bridging; structural molecule activity

Biological Process: keratinocyte differentiation; isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; keratinization; peptide cross-linking; response to UV-B
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 Research Articles on iNV    1. involucrin is up-regulated in psoriatic keratinocytes
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with iNV elisa kitPathways associated with iNV elisa kit
 Reference Product  PubMed Publications
 LOR elisa kit  >4 publications with iNV and LOR
 SPRR3 elisa kit  >2 publications with iNV and SPRR3
 KRT1 elisa kit  >1 publications with iNV and KRT1
 JUNB elisa kit  >1 publications with iNV and JUNB
 Products by Pathway  Pathway Diagram
 Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway antibodies  Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway Diagram
Diseases associated with iNV elisa kitOrgans/Tissues associated with iNV elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >184 publications with iNV and Neoplasms
 Skin Neoplasms Antibodies  >43 publications with iNV and Skin Neoplasms
 Brain Diseases Antibodies  >37 publications with iNV and Brain Diseases
 Lung Neoplasms Antibodies  >26 publications with iNV and Lung Neoplasms
 Drug Toxicity Antibodies  >18 publications with iNV and Drug Toxicity
 Heart Diseases Antibodies  >16 publications with iNV and Heart Diseases
 Neoplasm Invasiveness Antibodies  >15 publications with iNV and Neoplasm Invasiveness
 Liver Neoplasms Antibodies  >15 publications with iNV and Liver Neoplasms
 Anemia Antibodies  >12 publications with iNV and Anemia
 Edema Antibodies  >11 publications with iNV and Edema
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >71 publications with iNV and Skin
 Brain Antibodies  >55 publications with iNV and Brain
 Muscle Antibodies  >38 publications with iNV and Muscle
 Lung Antibodies  >33 publications with iNV and Lung
 Esophagus Antibodies  >3 publications with iNV and Esophagus
 Prostate Antibodies  >3 publications with iNV and Prostate
 Larynx Antibodies  >2 publications with iNV and Larynx
 Mouth Antibodies  >2 publications with iNV and Mouth
 Mammary Gland Antibodies  >1 publications with iNV and Mammary Gland
 Bladder Antibodies  >1 publications with iNV and Bladder
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