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IDH1 elisa kit :: Human Isocitrate Dehydrogenase 1, Soluble (IDH1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS450967
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $400 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,425 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,710 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Isocitrate Dehydrogenase 1, Soluble (IDH1), ELISA Kit

★Popular Item★
 Also Known As   

Human Isocitrate Dehydrogenase 1, Soluble (IDH1) ELISA Kit

 Product Synonym Names    PICD; IDP; Oxalosuccinate decarboxylase; NADP(+)-specific ICDH; Cytosolic NADP-isocitrate dehydrogenase
 Product Gene Name   

IDH1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    AF020038 mRNA
 3D Structure    ModBase 3D Structure for O75874
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 Species Reactivity    Human
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 Samples    Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
 Assay Type    Sandwich
 Detection Range    3.125-200ng/mL
 Sensitivity    1.26ng/mL
 Intra Assay    CV<10%
 Inter Assay    CV<12%
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 Preparation and Storage    For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IDH1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IDH1 purchase    MBS450967 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Isocitrate Dehydrogenase 1, Soluble (IDH1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.125-200ng/mL in biological research samples containing IDH1, with an estimated sensitivity of 1.26ng/mL. The ELISA analytical biochemical technique of the MBS450967 kit is based on IDH1 antibody-IDH1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IDH1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IDH1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of IDH1 elisa kit    IDH1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS450967. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IDH1. It may not necessarily be applicable to this product.
 NCBI GI #    538917488
 NCBI GeneID    3417
 NCBI Accession #    NP_001269315.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001282386.1 [Other Products]
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 UniProt Primary Accession #    O75874 [Other Products]
 UniProt Secondary Accession #    Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8 [Other Products]
 UniProt Related Accession #    O75874 [Other Products]
 Molecular Weight    46,659 Da
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 NCBI Official Full Name    isocitrate dehydrogenase
 NCBI Official Synonym Full Names    isocitrate dehydrogenase (NADP(+)) 1, cytosolic
 NCBI Official Symbol    IDH1 [Similar Products]
 NCBI Official Synonym Symbols   
IDH; IDP; IDCD; IDPC; PICD; HEL-216; HEL-S-26
[Similar Products]
 NCBI Protein Information    isocitrate dehydrogenase [NADP] cytoplasmic
 UniProt Protein Name    Isocitrate dehydrogenase [NADP] cytoplasmic
 UniProt Synonym Protein Names   
Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
 Protein Family    Isocitrate dehydrogenase
 UniProt Gene Name    IDH1 [Similar Products]
 UniProt Synonym Gene Names    PICD; IDH [Similar Products]
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 NCBI Summary for IDH1    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]
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 Research Articles on IDH1    1. In patients with glioblastoma multiforme, less than a quarter of our patients' long-term survivorship was associated with favorable IDH1 status.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IDH1 elisa kitPathways associated with IDH1 elisa kit
 Reference Product  PubMed Publications
 MDH1 elisa kit  >10 publications with IDH1 and MDH1
 ACO1 elisa kit  >8 publications with IDH1 and ACO1
 ACLY elisa kit  >5 publications with IDH1 and ACLY
 GOT1 elisa kit  >2 publications with IDH1 and GOT1
 ACO2 elisa kit  >2 publications with IDH1 and ACO2
 GLUD1 elisa kit  >1 publications with IDH1 and GLUD1
 GOT2 elisa kit  >1 publications with IDH1 and GOT2
 IDH3B elisa kit  >1 publications with IDH1 and IDH3B
 IDH3A elisa kit  >1 publications with IDH1 and IDH3A
 Products by Pathway  Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 Abnormal Conversion Of 2-oxoglutarate To 2-hydroxyglutarate Pathway antibodies  Abnormal Conversion Of 2-oxoglutarate To 2-hydroxyglutarate Pathway Diagram
 Amino Acid Metabolism Pathway antibodies  Amino Acid Metabolism Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
Diseases associated with IDH1 elisa kitOrgans/Tissues associated with IDH1 elisa kit
 Disease Name  Pubmed Publications
 Glioma Antibodies  >981 publications with IDH1 and Glioma
 Nervous System Diseases Antibodies  >744 publications with IDH1 and Nervous System Diseases
 Leukemia, Myeloid, Acute Antibodies  >314 publications with IDH1 and Leukemia, Myeloid, Acute
 Oligodendroglioma Antibodies  >187 publications with IDH1 and Oligodendroglioma
 Cell Transformation, Neoplastic Antibodies  >64 publications with IDH1 and Cell Transformation, Neoplastic
 Cholangiocarcinoma Antibodies  >45 publications with IDH1 and Cholangiocarcinoma
 Neoplasm Recurrence, Local Antibodies  >44 publications with IDH1 and Neoplasm Recurrence, Local
 Neoplasms, Experimental Antibodies  >42 publications with IDH1 and Neoplasms, Experimental
 Necrosis Antibodies  >38 publications with IDH1 and Necrosis
 Liver Neoplasms Antibodies  >24 publications with IDH1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >853 publications with IDH1 and Brain
 Blood Antibodies  >166 publications with IDH1 and Blood
 Bone Antibodies  >104 publications with IDH1 and Bone
 Bone Marrow Antibodies  >61 publications with IDH1 and Bone Marrow
 Liver Antibodies  >49 publications with IDH1 and Liver
 Vascular Antibodies  >42 publications with IDH1 and Vascular
 Nerve Antibodies  >34 publications with IDH1 and Nerve
 Lung Antibodies  >23 publications with IDH1 and Lung
 Prostate Antibodies  >15 publications with IDH1 and Prostate
 Skin Antibodies  >13 publications with IDH1 and Skin
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