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KISS1 elisa kit :: Human Kisspeptin 1 (KISS1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS454153 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $370 +1 FREE 8GB USB
96-Strip-Wells  /  $495 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,200 +2 FREE 8GB USB
10x96-Strip-Wells  /  $4,265 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Kisspeptin 1 (KISS1), ELISA Kit

★Popular Item★
 Also Known As   

Human Kisspeptin 1 (KISS1) ELISA Kit

 Product Synonym Names    Metastin; KiSS-1 Metastasis-Suppressor
 Product Gene Name   

KISS1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    U43527 mRNA
 3D Structure    ModBase 3D Structure for Q15726
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 Species Reactivity    Human
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 Samples    Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
 Assay Type    Sandwich
 Detection Range    31.25-2000pg/mL
 Sensitivity    12.9pg/mL
 Intra Assay    CV<10%
 Inter Assay    CV<12%
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 Preparation and Storage    For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of KISS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for KISS1 purchase    MBS454153 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Kisspeptin 1 (KISS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25-2000pg/mL in biological research samples containing KISS1, with an estimated sensitivity of 12.9pg/mL. The ELISA analytical biochemical technique of the MBS454153 kit is based on KISS1 antibody-KISS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KISS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KISS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of KISS1 elisa kit    KISS1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS454153. Click to request current manual
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NCBI/Uniprot data below describe general gene information for KISS1. It may not necessarily be applicable to this product.
 NCBI GI #    116829964
 NCBI GeneID    3814
 NCBI Accession #    NP_002247.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_002256.3 [Other Products]
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 UniProt Primary Accession #    Q15726 [Other Products]
 UniProt Secondary Accession #    Q9HBP1; A8K6N0 [Other Products]
 UniProt Related Accession #    Q15726 [Other Products]
 Molecular Weight    14,705 Da
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 NCBI Official Full Name    metastasis-suppressor KiSS-1 preproprotein
 NCBI Official Synonym Full Names    KiSS-1 metastasis-suppressor
 NCBI Official Symbol    KISS1 [Similar Products]
 NCBI Official Synonym Symbols   
HH13; KiSS-1
[Similar Products]
 NCBI Protein Information    metastasis-suppressor KiSS-1
 UniProt Protein Name    Metastasis-suppressor KiSS-1
 UniProt Synonym Protein Names   
Kisspeptin-1
 Protein Family    Metastasis-suppressor
 UniProt Gene Name    KISS1 [Similar Products]
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 NCBI Summary for KISS1    This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]
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 UniProt Comments for KISS1    Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca2+ levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
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 Research Articles on KISS1    1. There is an increasing appreciation that kisspeptin may act as a signal transmitter between metabolic status and reproductive function
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with KISS1 elisa kitPathways associated with KISS1 elisa kit
 Reference Product  PubMed Publications
 KISS1R elisa kit  >421 publications with KISS1 and KISS1R
 GNRH1 elisa kit  >49 publications with KISS1 and GNRH1
 TAC3 elisa kit  >25 publications with KISS1 and TAC3
 GNRHR elisa kit  >24 publications with KISS1 and GNRHR
 TACR3 elisa kit  >22 publications with KISS1 and TACR3
 GNRH2 elisa kit  >18 publications with KISS1 and GNRH2
 PROKR2 elisa kit  >9 publications with KISS1 and PROKR2
 NPFFR1 elisa kit  >1 publications with KISS1 and NPFFR1
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with KISS1 elisa kitOrgans/Tissues associated with KISS1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >109 publications with KISS1 and Neoplasm Metastasis
 Genital Diseases, Female Antibodies  >68 publications with KISS1 and Genital Diseases, Female
 Male Urogenital Diseases Antibodies  >67 publications with KISS1 and Male Urogenital Diseases
 Puberty, Precocious Antibodies  >64 publications with KISS1 and Puberty, Precocious
 Infertility, Female Antibodies  >62 publications with KISS1 and Infertility, Female
 Breast Neoplasms Antibodies  >50 publications with KISS1 and Breast Neoplasms
 Puberty, Delayed Antibodies  >47 publications with KISS1 and Puberty, Delayed
 Infertility, Male Antibodies  >40 publications with KISS1 and Infertility, Male
 Adenocarcinoma Antibodies  >35 publications with KISS1 and Adenocarcinoma
 Disorders of Sex Development Antibodies  >25 publications with KISS1 and Disorders of Sex Development
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >726 publications with KISS1 and Brain
 Placenta Antibodies  >70 publications with KISS1 and Placenta
 Testis Antibodies  >68 publications with KISS1 and Testis
 Embryonic Tissue Antibodies  >28 publications with KISS1 and Embryonic Tissue
 Prostate Antibodies  >24 publications with KISS1 and Prostate
 Lung Antibodies  >17 publications with KISS1 and Lung
 Bone Antibodies  >15 publications with KISS1 and Bone
 Skin Antibodies  >12 publications with KISS1 and Skin
 Heart Antibodies  >11 publications with KISS1 and Heart
 Intestine Antibodies  >7 publications with KISS1 and Intestine
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