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KLF2 elisa kit :: Human Kruppel-like factor 2 (lung) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS931735
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Kruppel-like factor 2 (lung) (KLF2), ELISA Kit

★Popular Item★
 Also Known As   

Human Krueppel-like factor 2, KLF2 ELISA Kit

 Product Synonym Names    Human Krueppel-like factor 2 (KLF2) ELISA kit; LKLF; Kruppel-like factor; Kruppel-like factor LKLF; lung Kruppel-like zinc finger transcription factor; Kruppel-like factor 2 (lung)
 Product Gene Name   

KLF2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS931735 Testing Data    Testing Data PDF
 OMIM    602016
 3D Structure    ModBase 3D Structure for Q9Y5W3
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human KLF2. No significant cross-reactivity or interference between human KLF2 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates.
 Assay Type    Sandwich
 Detection Range    15.6 pg/ml -1000 pg/ml.
 Sensitivity    3.9 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of KLF2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for KLF2 purchase    MBS931735 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Kruppel-like factor 2 (lung) (KLF2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6 pg/ml -1000 pg/ml in biological research samples containing KLF2, with an estimated sensitivity of 3.9 pg/ml. The ELISA analytical biochemical technique of the MBS931735 kit is based on KLF2 antibody-KLF2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KLF2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KLF2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for KLF2 elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for KLF2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any KLF2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for KLF2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of KLF2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of KLF2 elisa kit    KLF2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS931735. Click to request current manual
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NCBI/Uniprot data below describe general gene information for KLF2. It may not necessarily be applicable to this product.
 NCBI GI #    7706469
 NCBI GeneID    10365
 NCBI Accession #    NP_057354.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016270.2 [Other Products]
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 UniProt Primary Accession #    Q9Y5W3 [Other Products]
 UniProt Secondary Accession #    Q6IPC4; Q9UJS5; Q9UKR6 [Other Products]
 UniProt Related Accession #    Q9Y5W3 [Other Products]
 Molecular Weight    37,420 Da
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 NCBI Official Full Name    Krueppel-like factor 2
 NCBI Official Synonym Full Names    Kruppel-like factor 2
 NCBI Official Symbol    KLF2 [Similar Products]
 NCBI Official Synonym Symbols   
LKLF
[Similar Products]
 NCBI Protein Information    Krueppel-like factor 2; Kruppel-like factor LKLF; lung krueppel-like factor; Kruppel-like factor 2 (lung); lung Kruppel-like zinc finger transcription factor
 UniProt Protein Name    Krueppel-like factor 2
 UniProt Synonym Protein Names   
Lung krueppel-like factor
 Protein Family    Krueppel-like factor
 UniProt Gene Name    KLF2 [Similar Products]
 UniProt Synonym Gene Names    LKLF [Similar Products]
 UniProt Entry Name    KLF2_HUMAN
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 NCBI Summary for KLF2    Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]
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 UniProt Comments for KLF2    KLF2: Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: nucleus

Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding; transcription factor activity

Biological Process: erythrocyte maturation; transcription, DNA-dependent; in utero embryonic development; multicellular organism growth; negative regulation of interleukin-6 production; cell morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein metabolic process; regulation of gene expression, epigenetic
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 Research Articles on KLF2    1. The observations identify KLF2 as a novel negative regulator of DC function and it may play an essential role in DC activation in ACS.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with KLF2 elisa kitPathways associated with KLF2 elisa kit
 Reference Product  PubMed Publications
 NOS3 elisa kit  >13 publications with KLF2 and NOS3
 FOXO1 elisa kit  >10 publications with KLF2 and FOXO1
 PPARG elisa kit  >8 publications with KLF2 and PPARG
 THBD elisa kit  >4 publications with KLF2 and THBD
 S1PR1 elisa kit  >4 publications with KLF2 and S1PR1
 SELL elisa kit  >3 publications with KLF2 and SELL
 WWP1 elisa kit  >3 publications with KLF2 and WWP1
 PDGFB elisa kit  >2 publications with KLF2 and PDGFB
 Products by Pathway  Pathway Diagram
 FoxO Signaling Pathway antibodies  FoxO Signaling Pathway Diagram
Diseases associated with KLF2 elisa kitOrgans/Tissues associated with KLF2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >62 publications with KLF2 and Inflammation
 Atherosclerosis Antibodies  >49 publications with KLF2 and Atherosclerosis
 Necrosis Antibodies  >26 publications with KLF2 and Necrosis
 Heart Diseases Antibodies  >19 publications with KLF2 and Heart Diseases
 Disease Models, Animal Antibodies  >19 publications with KLF2 and Disease Models, Animal
 Lung Diseases Antibodies  >14 publications with KLF2 and Lung Diseases
 Hypertension Antibodies  >10 publications with KLF2 and Hypertension
 Anemia Antibodies  >8 publications with KLF2 and Anemia
 Liver Diseases Antibodies  >7 publications with KLF2 and Liver Diseases
 Carcinoma Antibodies  >7 publications with KLF2 and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >24 publications with KLF2 and Heart
 Muscle Antibodies  >22 publications with KLF2 and Muscle
 Bone Marrow Antibodies  >7 publications with KLF2 and Bone Marrow
 Adipose Tissue Antibodies  >6 publications with KLF2 and Adipose Tissue
 Eye Antibodies  >3 publications with KLF2 and Eye
 Pancreas Antibodies  >2 publications with KLF2 and Pancreas
 Thyroid Antibodies  >2 publications with KLF2 and Thyroid
 Brain Antibodies  >1 publications with KLF2 and Brain
 Placenta Antibodies  >1 publications with KLF2 and Placenta
 Uncharacterized Tissue Antibodies  >1 publications with KLF2 and Uncharacterized Tissue
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