NP_001158886.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,712 Da
NCBI Official Full Name
L-lactate dehydrogenase A chain isoform 3
NCBI Official Synonym Full Names
lactate dehydrogenase A
NCBI Official Synonym Symbols
LDH1; LDHM; GSD11; PIG19; HEL-S-133P [Similar Products]
NCBI Protein Information
L-lactate dehydrogenase A chain; LDH-A; LDH-M; LDH muscle subunit; lactate dehydrogenase M; proliferation-inducing gene 19; renal carcinoma antigen NY-REN-59; cell proliferation-inducing gene 19 protein; epididymis secretory sperm binding protein Li 133P
UniProt Protein Name
L-lactate dehydrogenase A chain
UniProt Synonym Protein Names
Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59
UniProt Synonym Gene Names
UniProt Entry Name
LDHA_HUMAN
NCBI Summary for LDHA
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
UniProt Comments for LDHA
LDH-A: Homotetramer. Belongs to the LDH/MDH superfamily. LDH family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.1.1.27; Oxidoreductase; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; Apoptosis; Amino Acid Metabolism - cysteine and methionine; Carbohydrate Metabolism - glycolysis and gluconeogenesis
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: mitochondrion; membrane; cytosol; nucleus
Molecular Function: protein binding; L-lactate dehydrogenase activity
Biological Process: cellular metabolic process; glycolysis; substantia nigra development; cellular response to extracellular stimulus; cellular carbohydrate metabolic process; pyruvate metabolic process
Disease: Glycogen Storage Disease Xi
Research Articles on LDHA
Precautions
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Products associated with LDHA elisa kit
Pathways associated with LDHA elisa kit
Diseases associated with LDHA elisa kit
Organs/Tissues associated with LDHA elisa kit
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