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LEFTY1 elisa kit :: Human LEFTY1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2515962
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LEFTY1, ELISA Kit

★Popular Item★
 Also Known As   

Human LEFTY1(Left/Right Determination Factor 1)ELISA Kit

 Product Gene Name   

LEFTY1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    603037
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinantHumanLEFTY1. No significant cross-reactivity or interference between HumanLEFTY1 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    Min: 0.188ng/mL; Max: 20ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LEFTY1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LEFTY1 purchase    MBS2515962 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LEFTY1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing LEFTY1, with an estimated sensitivity of Min: 0.188ng/mL; Max: 20ng/mL. The ELISA analytical biochemical technique of the MBS2515962 kit is based on LEFTY1 antibody-LEFTY1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LEFTY1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LEFTY1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LEFTY1 elisa kit

   Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanLEFTY1concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to LEFTY1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for LEFTY1and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain LEFTY1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of LEFTY1.You can calculate the concentration of LEFTY1in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of LEFTY1 elisa kit    LEFTY1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2515962. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LEFTY1. It may not necessarily be applicable to this product.
 NCBI GI #    10337603
 NCBI GeneID    10637
 NCBI Accession #    NP_066277.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020997.3 [Other Products]
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 UniProt Secondary Accession #    Q53H67; Q5TE94; B2R7U0 [Other Products]
 UniProt Related Accession #    O75610 [Other Products]
 Molecular Weight    40,880 Da
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 NCBI Official Full Name    left-right determination factor 1 preproprotein
 NCBI Official Synonym Full Names    left-right determination factor 1
 NCBI Official Symbol    LEFTY1 [Similar Products]
 NCBI Official Synonym Symbols   
LEFTB; LEFTYB
[Similar Products]
 NCBI Protein Information    left-right determination factor 1; left-right determination factor B; left-right determination, factor B; protein lefty-1; protein lefty-B
 UniProt Protein Name    Left-right determination factor 1
 UniProt Synonym Protein Names   
Left-right determination factor B; Protein lefty-1; Protein lefty-B
 Protein Family    Left-right determination factor
 UniProt Gene Name    LEFTY1 [Similar Products]
 UniProt Synonym Gene Names    LEFTB; LEFTYB [Similar Products]
 UniProt Entry Name    LFTY1_HUMAN
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 NCBI Summary for LEFTY1    This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for LEFTY1    LEFTY1: Required for left-right axis determination as a regulator of LEFTY2 and NODAL. Belongs to the TGF-beta family.

Protein type: Motility/polarity/chemotaxis; Cytokine; Secreted, signal peptide; Ligand, receptor tyrosine kinase; Secreted

Chromosomal Location of Human Ortholog: 1q42.1

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: heart morphogenesis; regulation of apoptosis; transforming growth factor beta receptor signaling pathway; regulation of MAPKKK cascade; negative regulation of transcription from RNA polymerase II promoter; determination of left/right symmetry; cell growth; cell development
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 Research Articles on LEFTY1    1. The mRNA levels of LSD1 and beta-catenin are inversely correlated with the levels of Lefty1 in pancreas and breast tumors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LEFTY1 elisa kitPathways associated with LEFTY1 elisa kit
 Reference Product  PubMed Publications
 NODAL elisa kit  >78 publications with LEFTY1 and NODAL
 PITX2 elisa kit  >25 publications with LEFTY1 and PITX2
 CFC1 elisa kit  >7 publications with LEFTY1 and CFC1
 OCT4 elisa kit  >7 publications with LEFTY1 and OCT4
 ZIC3 elisa kit  >4 publications with LEFTY1 and ZIC3
 ACVR2B elisa kit  >4 publications with LEFTY1 and ACVR2B
 TGFB3 elisa kit  >2 publications with LEFTY1 and TGFB3
 TGFB1 elisa kit  >2 publications with LEFTY1 and TGFB1
 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Regulation Of Signaling By NODAL Pathway antibodies  Regulation Of Signaling By NODAL Pathway Diagram
 Signaling By NODAL Pathway antibodies  Signaling By NODAL Pathway Diagram
 TGF Beta Signaling Pathway antibodies  TGF Beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
Diseases associated with LEFTY1 elisa kitOrgans/Tissues associated with LEFTY1 elisa kit
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >11 publications with LEFTY1 and Heart Diseases
 Carcinoma Antibodies  >2 publications with LEFTY1 and Carcinoma
 Breast Neoplasms Antibodies  >2 publications with LEFTY1 and Breast Neoplasms
 Edema Antibodies  >1 publications with LEFTY1 and Edema
 Nervous System Malformations Antibodies  >1 publications with LEFTY1 and Nervous System Malformations
 Kidney Diseases Antibodies  >1 publications with LEFTY1 and Kidney Diseases
 Nervous System Diseases Antibodies  >1 publications with LEFTY1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with LEFTY1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >18 publications with LEFTY1 and Embryonic Tissue
 Brain Antibodies  >13 publications with LEFTY1 and Brain
 Uterus Antibodies  >8 publications with LEFTY1 and Uterus
 Pancreas Antibodies  >6 publications with LEFTY1 and Pancreas
 Stomach Antibodies  >3 publications with LEFTY1 and Stomach
 Ovary Antibodies  >1 publications with LEFTY1 and Ovary
 Intestine Antibodies  >1 publications with LEFTY1 and Intestine
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