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LIMD1 elisa kit :: Human LIM domains containing 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9333468 LIMD1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LIM domains containing 1 (LIMD1), ELISA Kit

★Popular Item★
 Also Known As   

Human LIM domain-containing protein 1, LIMD1 ELISA Kit

 Product Synonym Names    Human LIM domain-containing protein 1 (LIMD1) ELISA kit; LIM domains containing 1
 Product Gene Name   

LIMD1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    604543
 3D Structure    ModBase 3D Structure for Q9UGP4
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    6.25 ng/ml - 200 ng/ml
 Sensitivity    1.0 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LIMD1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LIMD1 purchase    MBS9333468 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LIM domains containing 1 (LIMD1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 6.25 ng/ml - 200 ng/ml in biological research samples containing LIMD1, with an estimated sensitivity of 1.0 ng/ml. The ELISA analytical biochemical technique of the MBS9333468 kit is based on LIMD1 antibody-LIMD1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LIMD1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LIMD1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LIMD1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LIMD1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9333468. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LIMD1. It may not necessarily be applicable to this product.
 NCBI GI #    7657307
 NCBI GeneID    8994
 NCBI Accession #    NP_055055.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_014240.2 [Other Products]
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 UniProt Primary Accession #    Q9UGP4 [Other Products]
 UniProt Secondary Accession #    Q17RQ1; Q9BQQ9; Q9NQ47 [Other Products]
 UniProt Related Accession #    Q9UGP4 [Other Products]
 Molecular Weight    72,190 Da
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 NCBI Official Full Name    LIM domain-containing protein 1
 NCBI Official Synonym Full Names    LIM domains containing 1
 NCBI Official Symbol    LIMD1 [Similar Products]
 NCBI Protein Information    LIM domain-containing protein 1
 UniProt Protein Name    LIM domain-containing protein 1
 Protein Family    LIM domain-containing protein
 UniProt Gene Name    LIMD1 [Similar Products]
 UniProt Entry Name    LIMD1_HUMAN
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 UniProt Comments for LIMD1    LIMD1: Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG- dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1- responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation. Belongs to the zyxin/ajuba family.

Protein type: Tumor suppressor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: focal adhesion; adherens junction; cytoplasm; nucleus

Molecular Function: protein binding; zinc ion binding; transcription corepressor activity

Biological Process: cell migration; transcription, DNA-dependent; multicellular organismal development; cytoskeleton organization and biogenesis; miRNA-mediated gene silencing; signal transduction; osteoblast development; regulation of cell shape; regulation of transcription, DNA-dependent; response to hypoxia; negative regulation of osteoblast differentiation; cytoplasmic mRNA processing body assembly; negative regulation of transcription, DNA-dependent; phosphorylation
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 Research Articles on LIMD1    1. Data show that the tumour suppressor protein LIMD1 acts as a molecular scaffold, simultaneously binding the PHDs and VHL, thereby assembling a PHD-LIMD1-VHL protein complex and creating an enzymatic niche that enables efficient degradation of HIF-1alpha.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LIMD1 elisa kitPathways associated with LIMD1 elisa kit
 Reference Product  PubMed Publications
 VHL elisa kit  >3 publications with LIMD1 and VHL
 EGLN1 elisa kit  >2 publications with LIMD1 and EGLN1
 Products by Pathway  Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
Diseases associated with LIMD1 elisa kitOrgans/Tissues associated with LIMD1 elisa kit
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >1 publications with LIMD1 and Heart Diseases
 Myocardial Ischemia Antibodies  >1 publications with LIMD1 and Myocardial Ischemia
 Liver Diseases Antibodies  >1 publications with LIMD1 and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with LIMD1 and Cardiovascular Diseases
 Hyperplasia Antibodies  >1 publications with LIMD1 and Hyperplasia
 Carcinoma, Hepatocellular Antibodies  >1 publications with LIMD1 and Carcinoma, Hepatocellular
 Inflammation Antibodies  >1 publications with LIMD1 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >1 publications with LIMD1 and Lymph Node
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