AAH65194.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,765 Da
NCBI Official Full Name
Lysophosphatidylcholine acyltransferase 3
NCBI Official Synonym Full Names
lysophosphatidylcholine acyltransferase 3
NCBI Official Synonym Symbols
C3F; LPCAT; LPSAT; OACT5; nessy; MBOAT5; LPLAT 5 [Similar Products]
NCBI Protein Information
lysophospholipid acyltransferase 5; lyso-PS acyltransferase; lyso-PC acyltransferase 3; putative protein similar to nessy; lysophosphatidylserine acyltransferase; 1-acylglycerophosphoserine O-acyltransferase; 1-acylglycerophosphocholine O-acyltransferase; O-acyltransferase domain-containing protein 5; membrane bound O-acyltransferase domain containing 5; O-acyltransferase (membrane bound) domain containing 5; membrane-bound O-acyltransferase domain-containing protein 5
UniProt Protein Name
Lysophospholipid acyltransferase 5
UniProt Synonym Protein Names
1-acylglycerophosphocholine O-acyltransferase (EC:2.3.1.23); 1-acylglycerophosphoserine O-acyltransferase (EC:2.3.1.n6); Lysophosphatidylcholine acyltransferase; LPCAT; Lyso-PC acyltransferase; Lysophosphatidylcholine acyltransferase 3; Lyso-PC acyltransferase 3; Lysophosphatidylserine acyltransferase; LPSAT; Lyso-PS acyltransferase; Membrane-bound O-acyltransferase domain-containing protein 5; O-acyltransferase domain-containing protein 5
UniProt Synonym Gene Names
MBOAT5; OACT5; LPLAT 5; LPCAT; Lyso-PC acyltransferase; Lyso-PC acyltransferase 3; LPSAT; Lyso-PS acyltransferase; O-acyltransferase domain-containing protein 5 [Similar Products]
UniProt Entry Name
MBOA5_HUMAN
UniProt Comments for LPCAT3
MBOAT5: Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3- phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero- 3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. Belongs to the membrane-bound acyltransferase family.
Protein type: Membrane protein, multi-pass; EC 2.3.1.23; EC 2.3.1.n6; Transferase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane
Molecular Function: 1-acylglycerophosphocholine O-acyltransferase activity
Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process
Research Articles on LPCAT3
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Pathways associated with LPCAT3 elisa kit
Diseases associated with LPCAT3 elisa kit
Organs/Tissues associated with LPCAT3 elisa kit
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