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MAD1L1 elisa kit :: Human MAD1 mitotic arrest deficient-like 1 (yeast) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9338339 MAD1L1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1), ELISA Kit

 Also Known As   

Human Mitotic spindle assembly checkpoint protein MAD1, MAD1L1 ELISA Kit

 Product Synonym Names    Human Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1) ELISA kit; HsMAD1; MAD1; PIG9; TP53I9; TXBP181; MAD1-like 1 protein; OTTHUMP00000200097; OTTHUMP00000200099; mitotic-arrest deficient 1; yeast; homolog-like 1; tumor protein p53 inducible protein 9; MAD1 mitotic arrest deficient-like 1 (yeast)
 Product Gene Name   

MAD1L1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    602686
 3D Structure    ModBase 3D Structure for Q9Y6D9
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Other Notes    Small volumes of MAD1L1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MAD1L1 purchase    MBS9338339 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the MAD1 mitotic arrest deficient-like 1 (yeast) (MAD1L1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MAD1L1. The ELISA analytical biochemical technique of the MBS9338339 kit is based on MAD1L1 antibody-MAD1L1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MAD1L1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MAD1L1. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MAD1L1. It may not necessarily be applicable to this product.
 NCBI GI #    62243369
 NCBI GeneID    8379
 NCBI Accession #    NP_001013858.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001013836.1 [Other Products]
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 UniProt Primary Accession #    Q9Y6D9 [Other Products]
 UniProt Secondary Accession #    Q13312; Q75MI0; Q86UM4; Q9UNH0 [Other Products]
 UniProt Related Accession #    Q9Y6D9 [Other Products]
 Molecular Weight    83,067 Da
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 NCBI Official Full Name    mitotic spindle assembly checkpoint protein MAD1
 NCBI Official Synonym Full Names    MAD1 mitotic arrest deficient-like 1 (yeast)
 NCBI Official Symbol    MAD1L1 [Similar Products]
 NCBI Official Synonym Symbols   
MAD1; PIG9; TP53I9; TXBP181
[Similar Products]
 NCBI Protein Information    mitotic spindle assembly checkpoint protein MAD1; MAD1-like protein 1; tax-binding protein 181; tumor protein p53 inducible protein 9; mitotic checkpoint MAD1 protein homolog; mitotic arrest deficient 1-like protein 1; mitotic-arrest deficient 1, yeast, homolog-like 1
 UniProt Protein Name    Mitotic spindle assembly checkpoint protein MAD1
 UniProt Synonym Protein Names   
Mitotic arrest deficient 1-like protein 1; MAD1-like protein 1; Mitotic checkpoint MAD1 protein homolog; HsMAD1; hMAD1; Tax-binding protein 181
 Protein Family    Mitotic spindle assembly checkpoint protein
 UniProt Gene Name    MAD1L1 [Similar Products]
 UniProt Synonym Gene Names    MAD1; TXBP181; MAD1-like protein 1; HsMAD1; hMAD1 [Similar Products]
 UniProt Entry Name    MD1L1_HUMAN
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 NCBI Summary for MAD1L1    MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MAD1L1    MAD1L1: a component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Expressed weakly at G0/G1 and highly at late S and G2/M phase. Induced by p53. Becomes hyperphosphorylated in late S through M phases or after mitotic spindle damage. Two alternatively spliced isoforms have been described. Defects in MAD1L1 are involved in the development and/or progression of various types of cancer.

Protein type: Cell cycle regulation; Cytoskeletal

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: kinetochore; centrosome; cytoplasm; spindle; nuclear pore; nucleus; cytosol; actin cytoskeleton

Molecular Function: protein binding

Biological Process: mitosis; cell division; mitotic cell cycle checkpoint; mitotic cell cycle spindle assembly checkpoint; mitotic cell cycle

Disease: Prostate Cancer
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 Research Articles on MAD1L1    1. PRAP1 is a protein interacting partner of MAD1 and that PRAP1 is able to down-regulate MAD1 and suppress mitotic checkpoint signalling in hepatocellular carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MAD1L1 elisa kitPathways associated with MAD1L1 elisa kit
 Reference Product  PubMed Publications
 MAD2L1 elisa kit  >42 publications with MAD1L1 and MAD2L1
 MAX elisa kit  >36 publications with MAD1L1 and MAX
 SIN3A elisa kit  >10 publications with MAD1L1 and SIN3A
 tax elisa kit  >6 publications with MAD1L1 and tax
 SIN3B elisa kit  >4 publications with MAD1L1 and SIN3B
 NDC80 elisa kit  >4 publications with MAD1L1 and NDC80
 HDAC1 elisa kit  >4 publications with MAD1L1 and HDAC1
 COIL elisa kit  >3 publications with MAD1L1 and COIL
 NEK2 elisa kit  >2 publications with MAD1L1 and NEK2
 HDAC2 elisa kit  >2 publications with MAD1L1 and HDAC2
 Products by Pathway  Pathway Diagram
 Amplification Of Signal From Unattached Kinetochores Via A MAD2 Inhibitory Signal Pathway antibodies  Amplification Of Signal From Unattached Kinetochores Via A MAD2 Inhibitory Signal Pathway Diagram
 Amplification Of Signal From The Kinetochores Pathway antibodies  Amplification Of Signal From The Kinetochores Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
Diseases associated with MAD1L1 elisa kitOrgans/Tissues associated with MAD1L1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >47 publications with MAD1L1 and Neoplasms
 Carcinoma Antibodies  >17 publications with MAD1L1 and Carcinoma
 Leukemia Antibodies  >13 publications with MAD1L1 and Leukemia
 Chromosome Aberrations Antibodies  >10 publications with MAD1L1 and Chromosome Aberrations
 Adenocarcinoma Antibodies  >7 publications with MAD1L1 and Adenocarcinoma
 Breast Neoplasms Antibodies  >5 publications with MAD1L1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >5 publications with MAD1L1 and Lung Neoplasms
 Lung Diseases Antibodies  >5 publications with MAD1L1 and Lung Diseases
 Cell Transformation, Neoplastic Antibodies  >5 publications with MAD1L1 and Cell Transformation, Neoplastic
 Colorectal Neoplasms Antibodies  >4 publications with MAD1L1 and Colorectal Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16 publications with MAD1L1 and Blood
 Bone Antibodies  >8 publications with MAD1L1 and Bone
 Lung Antibodies  >7 publications with MAD1L1 and Lung
 Stomach Antibodies  >5 publications with MAD1L1 and Stomach
 Bone Marrow Antibodies  >5 publications with MAD1L1 and Bone Marrow
 Skin Antibodies  >4 publications with MAD1L1 and Skin
 Liver Antibodies  >3 publications with MAD1L1 and Liver
 Thymus Antibodies  >2 publications with MAD1L1 and Thymus
 Kidney Antibodies  >2 publications with MAD1L1 and Kidney
 Heart Antibodies  >2 publications with MAD1L1 and Heart
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