NP_944605.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,118 Da
NCBI Official Full Name
mas-related G-protein coupled receptor member D
NCBI Official Synonym Full Names
MAS-related GPR, member D
NCBI Official Synonym Symbols
NCBI Protein Information
mas-related G-protein coupled receptor member D; beta-alanine receptor; G-protein coupled receptor TGR7; mas-related G protein-coupled MRGD
UniProt Protein Name
Mas-related G-protein coupled receptor member D
UniProt Synonym Protein Names
Beta-alanine receptor; G-protein coupled receptor TGR7
UniProt Synonym Gene Names
UniProt Entry Name
MRGRD_HUMAN
UniProt Comments for MRGPRD
MRGPRD: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q13.3
Cellular Component: extracellular space; integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Research Articles on MRGPRD
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Products associated with MRGPRD elisa kit
Diseases associated with MRGPRD elisa kit
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