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MCRS1 elisa kit :: Human MCRS1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2506387
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Human MCRS1 (Microspherule Protein 1) ELISA Kit

 Product Gene Name   

MCRS1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    609504
 3D Structure    ModBase 3D Structure for Q96EZ8
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinant Human MCRS1. No significant cross-reactivity or interference between Human MCRS1 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    Min: 0.188ng/mL; Max: 20ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MCRS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MCRS1 purchase    MBS2506387 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the MCRS1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing MCRS1, with an estimated sensitivity of Min: 0.188ng/mL; Max: 20ng/mL. The ELISA analytical biochemical technique of the MBS2506387 kit is based on MCRS1 antibody-MCRS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MCRS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MCRS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for MCRS1 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human MCRS1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to MCRS1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for MCRS1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain MCRS1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of MCRS1. You can calculate the concentration of MCRS1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of MCRS1 elisa kit    MCRS1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2506387. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MCRS1. It may not necessarily be applicable to this product.
 NCBI GI #    507588242
 NCBI GeneID    10445
 NCBI Accession #    NP_001265270.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001278341.1 [Other Products]
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 UniProt Primary Accession #    Q96EZ8 [Other Products]
 UniProt Secondary Accession #    O14742; O75497; Q6VN53; Q7Z372 [Other Products]
 UniProt Related Accession #    Q96EZ8 [Other Products]
 Molecular Weight    31,134 Da
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 NCBI Official Full Name    microspherule protein 1 isoform 3
 NCBI Official Synonym Full Names    microspherule protein 1
 NCBI Official Symbol    MCRS1 [Similar Products]
 NCBI Official Synonym Symbols   
P78; MCRS2; MSP58; INO80Q; ICP22BP
[Similar Products]
 NCBI Protein Information    microspherule protein 1; 58 kDa microspherule protein; INO80 complex subunit J; INO80 complex subunit Q; cell cycle-regulated factor (78 kDa); cell cycle-regulated factor p78
 UniProt Protein Name    Microspherule protein 1
 UniProt Synonym Protein Names   
58 kDa microspherule protein; Cell cycle-regulated factor p78; INO80 complex subunit J; MCRS2
 Protein Family    Microspherule protein
 UniProt Gene Name    MCRS1 [Similar Products]
 UniProt Synonym Gene Names    INO80Q; MSP58 [Similar Products]
 UniProt Entry Name    MCRS1_HUMAN
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 UniProt Comments for MCRS1    MCRS1: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Nucleolus; RNA-binding

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: nucleoplasm; cytoplasm; nucleolus; cell junction; histone acetyltransferase complex; actin cytoskeleton

Molecular Function: protein binding; histone acetyltransferase activity (H4-K16 specific)

Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; regulation of transcription, DNA-dependent; protein modification process; DNA repair; DNA recombination
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 Research Articles on MCRS1    1. High expression of MSP58 was also an independent unfavorable prognostic factor.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MCRS1 elisa kitPathways associated with MCRS1 elisa kit
 Reference Product  PubMed Publications
 MYST1 elisa kit  >1 publications with MCRS1 and MYST1
 CHD4 elisa kit  >1 publications with MCRS1 and CHD4
 DAXX elisa kit  >1 publications with MCRS1 and DAXX
 Products by Pathway  Pathway Diagram
 Chromatin Modifying Enzymes Pathway antibodies  Chromatin Modifying Enzymes Pathway Diagram
 Chromatin Organization Pathway antibodies  Chromatin Organization Pathway Diagram
 HATs Acetylate Histones Pathway antibodies  HATs Acetylate Histones Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
Diseases associated with MCRS1 elisa kitOrgans/Tissues associated with MCRS1 elisa kit
 Disease Name  Pubmed Publications
 Liver Neoplasms Antibodies  >4 publications with MCRS1 and Liver Neoplasms
 Liver Diseases Antibodies  >4 publications with MCRS1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >3 publications with MCRS1 and Carcinoma, Hepatocellular
 Necrosis Antibodies  >2 publications with MCRS1 and Necrosis
 Death Antibodies  >1 publications with MCRS1 and Death
 Brain Diseases Antibodies  >1 publications with MCRS1 and Brain Diseases
 Edema Antibodies  >1 publications with MCRS1 and Edema
 Nervous System Diseases Antibodies  >1 publications with MCRS1 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with MCRS1 and Liver
 Lung Antibodies  >3 publications with MCRS1 and Lung
 Brain Antibodies  >3 publications with MCRS1 and Brain
 Lymph Antibodies  >1 publications with MCRS1 and Lymph
 Lymph Node Antibodies  >1 publications with MCRS1 and Lymph Node
 Mammary Gland Antibodies  >1 publications with MCRS1 and Mammary Gland
 Embryonic Tissue Antibodies  >1 publications with MCRS1 and Embryonic Tissue
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