NP_055753.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,806 Da
NCBI Official Full Name
MLX-interacting protein
NCBI Official Synonym Full Names
MLX interacting protein
NCBI Protein Information
MLX-interacting protein; Mlx interactor; transcriptional activator MondoA; class E basic helix-loop-helix protein 36
UniProt Protein Name
MLX-interacting protein
UniProt Synonym Protein Names
Class E basic helix-loop-helix protein 36; bHLHe36; Transcriptional activator MondoA
UniProt Synonym Gene Names
UniProt Entry Name
MLXIP_HUMAN
NCBI Summary for MLXIP
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]
UniProt Comments for MLXIP
MLXIP: Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. 5 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: mitochondrial outer membrane; nucleus
Molecular Function: protein dimerization activity; DNA binding; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent; nucleocytoplasmic transport
Research Articles on MLXIP
Precautions
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Diseases associated with MLXIP elisa kit
Organs/Tissues associated with MLXIP elisa kit
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