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MT2 elisa kit :: Human MT2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2503619
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Human MT2 (Metallothionein 2) ELISA Kit

 Product Gene Name   

MT2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600804
 3D Structure    ModBase 3D Structure for P49286
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinant Human MT2. No significant cross-reactivity or interference between Human MT2 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    The minimum detectable dose of Human MT2 is 0.188ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero).
 Intended Uses    This ELISA kit applies to the in vitro quantitative determination of Human MT2 concentrations in serum, plasma and other biological fluids.
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MT2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MT2 purchase    MBS2503619 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the MT2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing MT2, with an estimated sensitivity of The minimum detectable dose of Human MT2 is 0.188ng/mL (The sensitivity of this assay, or lowest detectable limit (LDL) was defined as the lowest protein concentration that could be differentiated from zero). The ELISA analytical biochemical technique of the MBS2503619 kit is based on MT2 antibody-MT2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MT2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MT2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for MT2 elisa kit

   Principle of the assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to MT2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for MT2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain MT2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of MT2. You can calculate the concentration of MT2 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of MT2 elisa kit    MT2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2503619. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MT2. It may not necessarily be applicable to this product.
 NCBI GI #    5174595
 NCBI GeneID    4544
 NCBI Accession #    NP_005950.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005959.3 [Other Products]
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 UniProt Primary Accession #    P49286 [Other Products]
 UniProt Related Accession #    P49286 [Other Products]
 Molecular Weight    40,188 Da
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 NCBI Official Full Name    melatonin receptor type 1B
 NCBI Official Synonym Full Names    melatonin receptor 1B
 NCBI Official Symbol    MTNR1B [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    melatonin receptor type 1B; mel1b receptor; melatonin receptor MEL1B
 UniProt Protein Name    Melatonin receptor type 1B
 Protein Family    Metallothionein
 UniProt Gene Name    MTNR1B [Similar Products]
 UniProt Synonym Gene Names    Mel-1B-R; Mel1b receptor [Similar Products]
 UniProt Entry Name    MTR1B_HUMAN
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 NCBI Summary for MT2    This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MT2    MTNR1B: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q21-q22

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; melatonin receptor activity

Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; glucose homeostasis; regulation of insulin secretion

Disease: Diabetes Mellitus, Noninsulin-dependent
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 Research Articles on MT2    1. We conclude that variation in MTNR1B contributes to the absolute level of insulin secretion but not to differences in the temporal rate of change in insulin secretion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MT2 elisa kitPathways associated with MT2 elisa kit
 Reference Product  PubMed Publications
 MTNR1A elisa kit  >27 publications with MT2 and MTNR1A
 ADCY5 elisa kit  >6 publications with MT2 and ADCY5
 ADRA2A elisa kit  >3 publications with MT2 and ADRA2A
 Products by Pathway  Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
Diseases associated with MT2 elisa kit
 Disease Name  Pubmed Publications
 Diabetes Mellitus, Type 2 Antibodies  >58 publications with MT2 and Diabetes Mellitus, Type 2
 Cardiovascular Diseases Antibodies  >5 publications with MT2 and Cardiovascular Diseases
 Hypertension Antibodies  >4 publications with MT2 and Hypertension
 Child Development Disorders, Pervasive Antibodies  >3 publications with MT2 and Child Development Disorders, Pervasive
 Adenocarcinoma Antibodies  >2 publications with MT2 and Adenocarcinoma
 Neurodegenerative Diseases Antibodies  >2 publications with MT2 and Neurodegenerative Diseases
 Polycystic Ovary Syndrome Antibodies  >2 publications with MT2 and Polycystic Ovary Syndrome
 Sleep Initiation and Maintenance Disorders Antibodies  >1 publications with MT2 and Sleep Initiation and Maintenance Disorders
 Depressive Disorder Antibodies  >1 publications with MT2 and Depressive Disorder
 Inflammation Antibodies  >1 publications with MT2 and Inflammation
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