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MVP elisa kit :: Human Major Vault Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS024048 MVP elisa kit
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Major Vault Protein (MVP), ELISA Kit

★Popular Item★
 Also Known As   

Human Major Vault Protein ELISA Kit

 Product Gene Name   

MVP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 16; NC_000016.9 (29831715..29859360). Location: 16p11.2
 OMIM    605088
 3D Structure    ModBase 3D Structure for Q14764
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Serum, Plasma and Tissue Homogenate
 Assay Type    Sandwich
 Detection Range    31.2pg/ml-1000pg/ml.
 Sensitivity    5.0pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MVP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MVP purchase    MBS024048 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Major Vault Protein (MVP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2pg/ml-1000pg/ml in biological research samples containing MVP, with an estimated sensitivity of 5.0pg/ml. The ELISA analytical biochemical technique of the MBS024048 kit is based on MVP antibody-MVP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MVP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MVP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma and Tissue Homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for MVP elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MVP (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS024048. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MVP. It may not necessarily be applicable to this product.
 NCBI GI #    19913412
 NCBI GeneID    9961
 NCBI Accession #    NP_005106.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005115.4 [Other Products]
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 UniProt Primary Accession #    Q14764 [Other Products]
 UniProt Secondary Accession #    Q96BG4; Q9BPW6; Q9BQT1; Q9UBD1 [Other Products]
 UniProt Related Accession #    Q14764 [Other Products]
 Molecular Weight    99,327 Da
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 NCBI Official Full Name    major vault protein
 NCBI Official Synonym Full Names    major vault protein
 NCBI Official Symbol    MVP [Similar Products]
 NCBI Official Synonym Symbols   
LRP; VAULT1
[Similar Products]
 NCBI Protein Information    major vault protein; lung resistance-related protein
 UniProt Protein Name    Major vault protein
 UniProt Synonym Protein Names   
Lung resistance-related protein
 Protein Family    Major vault protein
 UniProt Gene Name    MVP [Similar Products]
 UniProt Synonym Gene Names    LRP; MVP [Similar Products]
 UniProt Entry Name    MVP_HUMAN
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 NCBI Summary for MVP    This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
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 UniProt Comments for MVP    MVP: Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cytoskeleton; membrane; perinuclear region of cytoplasm; cytoplasm; nuclear pore; ribonucleoprotein complex; nucleus

Molecular Function: protein binding; protein kinase binding; protein phosphatase binding

Biological Process: cell proliferation; protein transport; mRNA transport; negative regulation of protein amino acid autophosphorylation
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 Research Articles on MVP    1. MVP and IGF-1R expression are related in oral squamous cell carcinoma and conferred reduced long-term survival in patients suffering from advanced stages of the disease
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MVP elisa kitDiseases associated with MVP elisa kit
 Reference Product  PubMed Publications
 ABCB1 elisa kit  >39 publications with MVP and ABCB1
 ABCC1 elisa kit  >6 publications with MVP and ABCC1
 PTEN elisa kit  >5 publications with MVP and PTEN
 ABCC3 elisa kit  >4 publications with MVP and ABCC3
 STAT1 elisa kit  >2 publications with MVP and STAT1
 PTPN11 elisa kit  >1 publications with MVP and PTPN11
 YPEL4 elisa kit  >1 publications with MVP and YPEL4
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >733 publications with MVP and Heart Diseases
 Neoplasms Antibodies  >282 publications with MVP and Neoplasms
 Drug Toxicity Antibodies  >77 publications with MVP and Drug Toxicity
 Brain Diseases Antibodies  >74 publications with MVP and Brain Diseases
 Neoplasm Metastasis Antibodies  >31 publications with MVP and Neoplasm Metastasis
 Fibrosis Antibodies  >30 publications with MVP and Fibrosis
 Hypertension Antibodies  >29 publications with MVP and Hypertension
 Hypertrophy Antibodies  >29 publications with MVP and Hypertrophy
 Disease Models, Animal Antibodies  >29 publications with MVP and Disease Models, Animal
 Myocardial Infarction Antibodies  >26 publications with MVP and Myocardial Infarction
Organs/Tissues associated with MVP elisa kit
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >521 publications with MVP and Heart
 Blood Antibodies  >253 publications with MVP and Blood
 Lung Antibodies  >208 publications with MVP and Lung
 Vascular Antibodies  >97 publications with MVP and Vascular
 Brain Antibodies  >77 publications with MVP and Brain
 Muscle Antibodies  >62 publications with MVP and Muscle
 Bone Antibodies  >56 publications with MVP and Bone
 Connective Tissue Antibodies  >42 publications with MVP and Connective Tissue
 Liver Antibodies  >32 publications with MVP and Liver
 Bladder Antibodies  >29 publications with MVP and Bladder
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