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MRC2 elisa kit :: Human Mannose Receptor C Type 2 (MRC2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS452201
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $375 +1 FREE 8GB USB
96-Strip-Wells  /  $495 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,225 +2 FREE 8GB USB
10x96-Strip-Wells  /  $4,320 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mannose Receptor C Type 2 (MRC2), ELISA Kit

★Popular Item★
 Also Known As   

Human Mannose Receptor C Type 2 (MRC2) ELISA Kit

 Product Synonym Names    PKC2; PKC-Z; PRKCZ; Protein Kinase M Zeta
 Product Gene Name   

MRC2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    AF107292 mRNA
 3D Structure    ModBase 3D Structure for Q9UBG0
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 Species Reactivity    Human
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 Samples    Serum, plasma, tissue homogenates and other biological fluids.
 Assay Type    Sandwich
 Detection Range    0.312-20ng/mL
 Sensitivity    0.117ng/mL
 Intra Assay    CV<10%
 Inter Assay    CV<12%
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 Preparation and Storage    For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MRC2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MRC2 purchase    MBS452201 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mannose Receptor C Type 2 (MRC2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.312-20ng/mL in biological research samples containing MRC2, with an estimated sensitivity of 0.117ng/mL. The ELISA analytical biochemical technique of the MBS452201 kit is based on MRC2 antibody-MRC2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MRC2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MRC2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of MRC2 elisa kit    MRC2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS452201. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MRC2. It may not necessarily be applicable to this product.
 NCBI GI #    110624774
 NCBI GeneID    9902
 NCBI Accession #    NP_006030.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006039.4 [Other Products]
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 UniProt Primary Accession #    Q9UBG0 [Other Products]
 UniProt Secondary Accession #    Q7LGE7; Q9Y5P9; A6H8K4; D3DU08 [Other Products]
 UniProt Related Accession #    Q9UBG0 [Other Products]
 Molecular Weight    166,674 Da
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 NCBI Official Full Name    C-type mannose receptor 2
 NCBI Official Synonym Full Names    mannose receptor C type 2
 NCBI Official Symbol    MRC2 [Similar Products]
 NCBI Official Synonym Symbols   
CD280; UPARAP; CLEC13E; ENDO180
[Similar Products]
 NCBI Protein Information    C-type mannose receptor 2
 UniProt Protein Name    C-type mannose receptor 2
 UniProt Synonym Protein Names   
C-type lectin domain family 13 member E; Endocytic receptor 180; Macrophage mannose receptor 2; Urokinase-type plasminogen activator receptor-associated protein; UPAR-associated protein; Urokinase receptor-associated protein; CD_antigen: CD280
 Protein Family    C-type mannose receptor
 UniProt Gene Name    MRC2 [Similar Products]
 UniProt Synonym Gene Names    CLEC13E; ENDO180; KIAA0709; UPARAP; UPAR-associated protein; Urokinase receptor-associated protein [Similar Products]
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 NCBI Summary for MRC2    This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]
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 UniProt Comments for MRC2    May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
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 Research Articles on MRC2    1. A model of the ligand-binding region of uPARAP was obtained by molecular replacement.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MRC2 elisa kitPathways associated with MRC2 elisa kit
 Reference Product  PubMed Publications
 PLAUR elisa kit  >5 publications with MRC2 and PLAUR
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway antibodies  Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
Diseases associated with MRC2 elisa kitOrgans/Tissues associated with MRC2 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >11 publications with MRC2 and Carcinoma
 Breast Neoplasms Antibodies  >6 publications with MRC2 and Breast Neoplasms
 Fibrosis Antibodies  >5 publications with MRC2 and Fibrosis
 Liver Diseases Antibodies  >5 publications with MRC2 and Liver Diseases
 Neoplasm Metastasis Antibodies  >5 publications with MRC2 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >5 publications with MRC2 and Disease Models, Animal
 Nervous System Diseases Antibodies  >5 publications with MRC2 and Nervous System Diseases
 Kidney Diseases Antibodies  >4 publications with MRC2 and Kidney Diseases
 Inflammation Antibodies  >3 publications with MRC2 and Inflammation
 Lung Diseases Antibodies  >3 publications with MRC2 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >12 publications with MRC2 and Blood
 Bone Antibodies  >9 publications with MRC2 and Bone
 Liver Antibodies  >7 publications with MRC2 and Liver
 Skin Antibodies  >7 publications with MRC2 and Skin
 Prostate Antibodies  >5 publications with MRC2 and Prostate
 Lung Antibodies  >5 publications with MRC2 and Lung
 Kidney Antibodies  >5 publications with MRC2 and Kidney
 Connective Tissue Antibodies  >4 publications with MRC2 and Connective Tissue
 Vascular Antibodies  >4 publications with MRC2 and Vascular
 Muscle Antibodies  >4 publications with MRC2 and Muscle
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