CAG29354.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,325 Da
NCBI Official Full Name
MGP, partial
NCBI Official Synonym Full Names
matrix Gla protein
NCBI Protein Information
matrix Gla protein; cell growth-inhibiting gene 36 protein
UniProt Protein Name
Matrix Gla protein
UniProt Synonym Protein Names
Cell growth-inhibiting gene 36 protein
UniProt Synonym Gene Names
UniProt Entry Name
MGP_HUMAN
NCBI Summary for MGP
The protein encoded by this gene is secreted and likely acts as an inhibitor of bone formation. The encoded protein is found in the organic matrix of bone and cartilage. Defects in this gene are a cause of Keutel syndrome (KS). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
UniProt Comments for MGP
MGP: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. Defects in MGP are the cause of Keutel syndrome (KS). KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. Belongs to the osteocalcin/matrix Gla protein family.
Protein type: Extracellular matrix; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: extracellular matrix; proteinaceous extracellular matrix
Molecular Function: protein binding; structural constituent of bone; extracellular matrix structural constituent; calcium ion binding
Biological Process: ossification; cell differentiation; regulation of bone mineralization; cartilage condensation
Disease: Keutel Syndrome
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Products associated with MGP elisa kit
Pathways associated with MGP elisa kit
Diseases associated with MGP elisa kit
Organs/Tissues associated with MGP elisa kit
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