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MBP Ab elisa kit :: Human Myelin Basic Protein Antibody (MBP Ab) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS267884
Typical Testing Data/Standard Curve
Unit / Price
48-Strip-Wells  /  $260 +1 FREE 8GB USB
96-Strip-Wells  /  $405 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
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 Product Name   

Myelin Basic Protein Antibody (MBP Ab), ELISA Kit

★Popular Item★
 Also Known As   

Human Myelin Basic Protein Antibody (MBP Ab) ELISA Kit

 Product Gene Name   

MBP Ab elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    614372
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 Species Reactivity    Human
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 Specificity    No cross-reaction with other factors.
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 Samples    Human serum, plasma or cell culture supernatant and organizations in the natural and recombinant MBP Ab concentration.
 Assay Type    Sandwich
 Detection Range    100 U/ml-1.56 U/ml
 Sensitivity    0.5 U/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MBP Ab elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MBP Ab purchase    MBS267884 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Myelin Basic Protein Antibody (MBP Ab) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 100 U/ml-1.56 U/ml in biological research samples containing MBP Ab, with an estimated sensitivity of 0.5 U/ml. The ELISA analytical biochemical technique of the MBS267884 kit is based on MBP Ab antibody-MBP Ab antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MBP Ab antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MBP Ab. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Human serum, plasma or cell culture supernatant and organizations in the natural and recombinant MBP Ab concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for MBP Ab elisa kit

   Principle of the Assay||This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human MBP Ab monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve of MBP Ab elisa kit    MBP Ab elisa kit Typical Testing Data/Standard Curve image
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Sample Manual Insert of MBS267884. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MBP Ab. It may not necessarily be applicable to this product.
 NCBI GI #    4557739
 NCBI GeneID    4153
 NCBI Accession #    NP_000233.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000242.2 [Other Products]
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 UniProt Secondary Accession #    Q4VB12; Q4VB13; Q4VB14; Q5SQS3; Q86SI4; Q96KE4; Q96TF7; Q96TF8; Q96TF9 [Other Products]
 UniProt Related Accession #    P11226 [Other Products]
 Molecular Weight    26,144 Da
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 NCBI Official Full Name    mannose-binding protein C
 NCBI Official Synonym Full Names    mannose-binding lectin (protein C) 2, soluble
 NCBI Official Symbol    MBL2 [Similar Products]
 NCBI Official Synonym Symbols   
MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC
[Similar Products]
 NCBI Protein Information    mannose-binding protein C; collectin-1; mannan-binding lectin; mannose-binding lectin 2, soluble (opsonic defect); mannose-binding lectin (protein C) 2, soluble (opsonic defect)
 UniProt Protein Name    Mannose-binding protein C
 UniProt Synonym Protein Names   
Collectin-1; MBP1; Mannan-binding protein; Mannose-binding lectin
 UniProt Gene Name    MBL2 [Similar Products]
 UniProt Synonym Gene Names    COLEC1; MBL; MBP-C [Similar Products]
 UniProt Entry Name    MBL2_HUMAN
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 NCBI Summary for MBP Ab    This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MBP Ab    MBL2: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: extracellular space; cell surface; collagen; extracellular region

Molecular Function: mannose binding; protein binding; calcium ion binding; calcium-dependent protein binding; receptor binding

Biological Process: defense response to Gram-positive bacterium; killing by host of symbiont cells; positive regulation of phagocytosis; defense response to bacterium; acute-phase response; innate immune response; response to oxidative stress; opsonization; complement activation, lectin pathway; complement activation, classical pathway; negative regulation of viral reproduction; complement activation

Disease: Mannose-binding Protein Deficiency
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 Research Articles on MBP Ab    1. Women with thyroid dysfunction and/or thyroid peroxidase antibodies (TPOAb) had lower MBL levels during pregnancy than controls
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MBP Ab elisa kitPathways associated with MBP Ab elisa kit
 Reference Product  PubMed Publications
 MASP2 elisa kit  >35 publications with MBP Ab and MASP2
 FCN2 elisa kit  >16 publications with MBP Ab and FCN2
 MASP1 elisa kit  >7 publications with MBP Ab and MASP1
 C1S elisa kit  >4 publications with MBP Ab and C1S
 INS elisa kit  >3 publications with MBP Ab and INS
 Products by Pathway  Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Lectin Pathway Of Complement Activation antibodies  Lectin Pathway Of Complement Activation Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
Diseases associated with MBP Ab elisa kitOrgans/Tissues associated with MBP Ab elisa kit
 Disease Name  Pubmed Publications
 Infection Antibodies  >200 publications with MBP Ab and Infection
 Inflammation Antibodies  >79 publications with MBP Ab and Inflammation
 Liver Diseases Antibodies  >31 publications with MBP Ab and Liver Diseases
 Fibrosis Antibodies  >27 publications with MBP Ab and Fibrosis
 HIV Infections Antibodies  >25 publications with MBP Ab and HIV Infections
 Hepatitis Antibodies  >20 publications with MBP Ab and Hepatitis
 Heart Diseases Antibodies  >19 publications with MBP Ab and Heart Diseases
 Necrosis Antibodies  >18 publications with MBP Ab and Necrosis
 Disease Models, Animal Antibodies  >13 publications with MBP Ab and Disease Models, Animal
 Atherosclerosis Antibodies  >12 publications with MBP Ab and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >45 publications with MBP Ab and Liver
 Mixed Antibodies  >3 publications with MBP Ab and Mixed
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