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MYO6 elisa kit :: Human Myosin VI (MYO6) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7228995 MYO6 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Myosin VI (MYO6), ELISA Kit

 Also Known As   

Human Myosin VI (MYO6) ELISA Kit

 Product Gene Name   

MYO6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    607821
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact technical support.
 Other Notes    Small volumes of MYO6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MYO6 purchase    MBS7228995 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Myosin VI (MYO6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MYO6. The ELISA analytical biochemical technique of the MBS7228995 kit is based on MYO6 antibody-MYO6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MYO6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MYO6. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for MYO6 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for MYO6. It may not necessarily be applicable to this product.
 NCBI GI #    12642366
 NCBI GeneID    4646
 NCBI Accession #    AAK00229.1 [Other Products]
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 UniProt Secondary Accession #    Q5TEM5; Q5TEM6; Q5TEM7; Q9BZZ7; Q9UEG2; A6H8V4; E1P540 [Other Products]
 UniProt Related Accession #    Q9UM54 [Other Products]
 Molecular Weight    148,659 Da
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 NCBI Official Full Name    myosin VI
 NCBI Official Synonym Full Names    myosin VI
 NCBI Official Symbol    MYO6 [Similar Products]
 NCBI Official Synonym Symbols   
DFNA22; DFNB37
[Similar Products]
 NCBI Protein Information    unconventional myosin-VI; unconventional myosin-6
 UniProt Protein Name    Unconventional myosin-VI
 UniProt Synonym Protein Names   
Unconventional myosin-6
 Protein Family    Unconventional myosin
 UniProt Gene Name    MYO6 [Similar Products]
 UniProt Synonym Gene Names    KIAA0389 [Similar Products]
 UniProt Entry Name    MYO6_HUMAN
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 NCBI Summary for MYO6    This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
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 UniProt Comments for MYO6    MYO6: a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins.

Protein type: Motility/polarity/chemotaxis; Motor; Actin-binding

Chromosomal Location of Human Ortholog: 6q13

Cellular Component: Golgi apparatus; nuclear membrane; microvillus; lysosomal membrane; cytoplasmic membrane-bound vesicle; clathrin coated vesicle membrane; coated pit; cell cortex; clathrin-coated endocytic vesicle; DNA-directed RNA polymerase II, holoenzyme; cytosol; nucleoplasm; filamentous actin; ruffle; membrane; cell soma; apical part of cell; axon; endocytic vesicle; perinuclear region of cytoplasm; cytoplasm; unconventional myosin complex; plasma membrane; nucleus

Molecular Function: calmodulin binding; actin filament binding; minus-end directed microfilament motor activity; protein binding; motor activity; ADP binding; actin binding; ATP binding

Biological Process: response to drug; inner ear morphogenesis; DNA damage response, signal transduction by p53 class mediator; actin filament-based movement; metabolic process; regulation of synaptic plasticity; endocytosis; regulation of secretion; locomotory behavior; auditory receptor cell differentiation; synaptic transmission; intracellular protein transport; sensory perception of sound; synaptogenesis; glutamate secretion; dendrite development; positive regulation of transcription from RNA polymerase II promoter; protein targeting

Disease: Deafness, Autosomal Recessive 37; Deafness, Autosomal Dominant 22
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 Research Articles on MYO6    1. Myo6 plays a critical role in the fusion of endosome/lysosome in Rmc epithelial cells. Deficiency of myo6 compromises the epithelial barrier function
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MYO6 elisa kitPathways associated with MYO6 elisa kit
 Reference Product  PubMed Publications
 GIPC1 elisa kit  >5 publications with MYO6 and GIPC1
 OTOF elisa kit  >2 publications with MYO6 and OTOF
 DAB2 elisa kit  >2 publications with MYO6 and DAB2
 OPTN elisa kit  >1 publications with MYO6 and OPTN
 Products by Pathway  Pathway Diagram
 Gap Junction Degradation Pathway antibodies  Gap Junction Degradation Pathway Diagram
 Gap Junction Trafficking Pathway antibodies  Gap Junction Trafficking Pathway Diagram
 Gap Junction Trafficking And Regulation Pathway antibodies  Gap Junction Trafficking And Regulation Pathway Diagram
 Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway antibodies  Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway antibodies  Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway Diagram
 Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway antibodies  Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway Diagram
 Trafficking Of AMPA Receptors Pathway antibodies  Trafficking Of AMPA Receptors Pathway Diagram
 Transmission Across Chemical Synapses Pathway antibodies  Transmission Across Chemical Synapses Pathway Diagram
Diseases associated with MYO6 elisa kitOrgans/Tissues associated with MYO6 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >23 publications with MYO6 and Nervous System Diseases
 Disease Models, Animal Antibodies  >4 publications with MYO6 and Disease Models, Animal
 Fibrosis Antibodies  >3 publications with MYO6 and Fibrosis
 Cardiomyopathies Antibodies  >2 publications with MYO6 and Cardiomyopathies
 Hypertension Antibodies  >1 publications with MYO6 and Hypertension
 Cell Transformation, Neoplastic Antibodies  >1 publications with MYO6 and Cell Transformation, Neoplastic
 Congenital Abnormalities Antibodies  >1 publications with MYO6 and Congenital Abnormalities
 Proteinuria Antibodies  >1 publications with MYO6 and Proteinuria
 Kidney Diseases Antibodies  >1 publications with MYO6 and Kidney Diseases
 Carcinoma, Squamous Cell Antibodies  >1 publications with MYO6 and Carcinoma, Squamous Cell
 Organ/Tissue Name  Pubmed Publications
 Ear Antibodies  >21 publications with MYO6 and Ear
 Brain Antibodies  >11 publications with MYO6 and Brain
 Intestine Antibodies  >4 publications with MYO6 and Intestine
 Kidney Antibodies  >4 publications with MYO6 and Kidney
 Prostate Antibodies  >3 publications with MYO6 and Prostate
 Embryonic Tissue Antibodies  >2 publications with MYO6 and Embryonic Tissue
 Blood Antibodies  >2 publications with MYO6 and Blood
 Bone Antibodies  >1 publications with MYO6 and Bone
 Nerve Antibodies  >1 publications with MYO6 and Nerve
 Eye Antibodies  >1 publications with MYO6 and Eye
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