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NAT8L elisa kit :: Human N-Acetyltransferase 8 Like Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS085684 NAT8L elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

N-Acetyltransferase 8 Like Protein (NAT8L), ELISA Kit

 Also Known As   

Human N-Acetyltransferase 8 Like Protein ELISA Kit

 Product Gene Name   

NAT8L elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    610647
 3D Structure    ModBase 3D Structure for Q8N9F0
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Serum, Plasma and Tissue Homogenate
 Assay Type    Sandwich
 Detection Range    0.25 ng/ml - 8 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Other Notes    Small volumes of NAT8L elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NAT8L purchase    MBS085684 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the N-Acetyltransferase 8 Like Protein (NAT8L) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 ng/ml - 8 ng/ml in biological research samples containing NAT8L, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS085684 kit is based on NAT8L antibody-NAT8L antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NAT8L antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NAT8L. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions such as Serum, Plasma and Tissue Homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for NAT8L elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NAT8L (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS085684
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NCBI/Uniprot data below describe general gene information for NAT8L. It may not necessarily be applicable to this product.
 NCBI GI #    259016335
 NCBI GeneID    339983
 NCBI Accession #    Q8N9F0.3 [Other Products]
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 UniProt Primary Accession #    Q8N9F0 [Other Products]
 UniProt Related Accession #    Q8N9F0 [Other Products]
 Molecular Weight    32,837 Da
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 NCBI Official Full Name    N-acetylaspartate synthetase
 NCBI Official Synonym Full Names    N-acetyltransferase 8-like (GCN5-related, putative)
 NCBI Official Symbol    NAT8L [Similar Products]
 NCBI Official Synonym Symbols   
CML3; NACED; NAT8-LIKE
[Similar Products]
 NCBI Protein Information    N-acetylaspartate synthetase; NAA synthetase; camello-like protein 3
 UniProt Protein Name    N-acetylaspartate synthetase
 UniProt Synonym Protein Names   
Camello-like protein 3; N-acetyltransferase 8-like protein
 Protein Family    N-acetylaspartate synthetase
 UniProt Gene Name    NAT8L [Similar Products]
 UniProt Synonym Gene Names    CML3; NAA synthetase [Similar Products]
 UniProt Entry Name    NAT8L_HUMAN
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 NCBI Summary for NAT8L    This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010]
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 UniProt Comments for NAT8L    NAT8L: Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. Defects in NAT8L are the cause of N-acetylaspartate deficiency (NACED). A metabolic disorder resulting in truncal ataxia, marked developmental delay, seizures, and secondary microcephaly. Belongs to the camello family.

Protein type: Acetyltransferase; EC 2.3.1.17; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: mitochondrion; cytoplasm; mitochondrial membrane; integral to membrane; rough endoplasmic reticulum membrane

Molecular Function: aspartate N-acetyltransferase activity

Biological Process: positive regulation of dopamine uptake; metabolic process

Disease: N-acetylaspartate Deficiency
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 Research Articles on NAT8L    1. Nat8l impacts on the brown adipogenic phenotype
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Human N-Acetyltransferase 8 Like Protein ELISA Kit
 Catalog #  Product Name  Catalog #  Product Name
 MBS099995  Cavy N-Acetyltransferase 8 Like Protein ELISA Kit  MBS2084065  HRP-Linked Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L)
 MBS058661  Donkey N-Acetyltransferase 8 Like Protein ELISA Kit  MBS2084060  APC/CY7-Linked Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L)
 MBS2084061  PE-Linked Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L)  MBS091540  Duck N-Acetyltransferase 8 Like Protein ELISA Kit
 MBS2033485  Recombinant N-Acetyltransferase 8 Like Protein (NAT8L)  MBS053537  Chicken N-Acetyltransferase 8 Like Protein ELISA Kit
 MBS097800  Sheep N-Acetyltransferase 8 Like Protein ELISA Kit  MBS091303  Goose N-Acetyltransferase 8 Like Protein ELISA Kit
Pathways associated with NAT8L elisa kitDiseases associated with NAT8L elisa kit
 Products by Pathway  Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Metapathway Biotransformation antibodies  Metapathway Biotransformation Diagram
 Disease Name  Pubmed Publications
 Abnormalities, Drug-Induced Antibodies  >1 publications with NAT8L and Abnormalities, Drug-Induced
Organs/Tissues associated with NAT8L elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with NAT8L and Brain
 Kidney Antibodies  >3 publications with NAT8L and Kidney
 Nerve Antibodies  >1 publications with NAT8L and Nerve
 Adipose Tissue Antibodies  >1 publications with NAT8L and Adipose Tissue
 Ovary Antibodies  >1 publications with NAT8L and Ovary
 Testis Antibodies  >1 publications with NAT8L and Testis
 Liver Antibodies  >1 publications with NAT8L and Liver
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