P51606.2
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,270 Da
NCBI Official Full Name
N-acylglucosamine 2-epimerase
NCBI Official Synonym Full Names
renin binding protein
NCBI Official Synonym Symbols
NCBI Protein Information
N-acylglucosamine 2-epimerase; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase
UniProt Protein Name
N-acylglucosamine 2-epimerase
UniProt Synonym Protein Names
GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; Renin-binding protein; RnBP
UniProt Synonym Gene Names
UniProt Entry Name
RENBP_HUMAN
NCBI Summary for RENBP
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]
UniProt Comments for RENBP
RENBP: Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Belongs to the N-acylglucosamine 2-epimerase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 5.1.3.8; Inhibitor; Isomerase
Chromosomal Location of Human Ortholog: Xq28
Molecular Function: protein homodimerization activity; endopeptidase inhibitor activity; N-acylglucosamine 2-epimerase activity; ATP binding
Biological Process: N-acetylneuraminate catabolic process; regulation of blood pressure; N-acetylglucosamine metabolic process; N-acetylmannosamine metabolic process
Research Articles on RENBP
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Products associated with RENBP elisa kit
Pathways associated with RENBP elisa kit
Diseases associated with RENBP elisa kit
Organs/Tissues associated with RENBP elisa kit
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