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NDUFA11 elisa kit :: Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9320067 NDUFA11 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa (NDUFA11), ELISA Kit

 Also Known As   

Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11, NDUFA11 ELISA Kit

 Product Synonym Names    Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (NDUFA11) ELISA kit; B14.7; NADH-ubiquinone oxidoreductase subunit B14.7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex; 11; 14.7kDa
 Product Gene Name   

NDUFA11 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    612638
 3D Structure    ModBase 3D Structure for Q86Y39
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NDUFA11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NDUFA11 purchase    MBS9320067 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa (NDUFA11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NDUFA11. The ELISA analytical biochemical technique of the MBS9320067 kit is based on NDUFA11 antibody-NDUFA11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NDUFA11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NDUFA11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NDUFA11. It may not necessarily be applicable to this product.
 NCBI GI #    301129187
 NCBI GeneID    126328
 NCBI Accession #    NP_001180304.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001193375.1 [Other Products]
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 UniProt Primary Accession #    Q86Y39 [Other Products]
 UniProt Secondary Accession #    Q6ZS66; C9JT23 [Other Products]
 UniProt Related Accession #    Q86Y39 [Other Products]
 Molecular Weight    14,852 Da
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 NCBI Official Full Name    NADH dehydrogenase
 NCBI Official Synonym Full Names    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
 NCBI Official Symbol    NDUFA11 [Similar Products]
 NCBI Official Synonym Symbols   
B14.7; CI-B14.7
[Similar Products]
 NCBI Protein Information    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11; complex I B14.7 subunit; NADH-ubiquinone oxidoreductase subunit B14.7
 UniProt Protein Name    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
 UniProt Synonym Protein Names   
Complex I-B14.7; CI-B14.7; NADH-ubiquinone oxidoreductase subunit B14.7
 Protein Family    NADH dehydrogenase
 UniProt Gene Name    NDUFA11 [Similar Products]
 UniProt Synonym Gene Names    CI-B14.7 [Similar Products]
 UniProt Entry Name    NDUAB_HUMAN
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 NCBI Summary for NDUFA11    This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
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 UniProt Comments for NDUFA11    NDUFA11: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in NDUFA11 are a cause of mitochondrial complex I deficiency (MT-C1D). A disorder of the mitochondrial respiratory chain that causes a wide range of clinical manifestations, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy and some forms of Parkinson disease. Belongs to the complex I NDUFA11 subunit family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: mitochondrion; mitochondrial inner membrane; integral to membrane; mitochondrial respiratory chain complex I

Biological Process: cellular metabolic process

Disease: Mitochondrial Complex I Deficiency
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 Research Articles on NDUFA11    1. study identified a splice-site mutation in the NDUFA11 gene in six mitochondrial complex I deficiency patients from three unrelated families
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NDUFA11 elisa kitDiseases associated with NDUFA11 elisa kit
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Parkinson's Disease Pathway antibodies  Parkinson's Disease Pathway Diagram
 Disease Name  Pubmed Publications
 Ischemic Attack, Transient Antibodies  >1 publications with NDUFA11 and Ischemic Attack, Transient
 Mitochondrial Diseases Antibodies  >1 publications with NDUFA11 and Mitochondrial Diseases
 MITOCHONDRIAL COMPLEX I DEFICIENCY Antibodies  >1 publications with NDUFA11 and MITOCHONDRIAL COMPLEX I DEFICIENCY
Organs/Tissues associated with NDUFA11 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with NDUFA11 and Brain
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