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NLRP7 elisa kit :: Human NLR family, pyrin domain containing 7 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9337822 NLRP7 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NLR family, pyrin domain containing 7 (NLRP7), ELISA Kit

 Also Known As   

Human NACHT, LRR and PYD domains-containing protein 7, NLRP7 ELISA Kit

 Product Synonym Names    Human NACHT; LRR and PYD domains-containing protein 7 (NLRP7) ELISA kit; CLR19.4; FLJ94610; HYDM; MGC126470; MGC126471; NALP7; NOD12; PAN7; PYPAF3; NACHT; LRR and PYD containing protein 7; NACHT; leucine rich repeat and PYD containing 7; PYRIN-containing Apaf1-like protein; NLR family; pyrin domain containing 7
 Product Gene Name   

NLRP7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    609661
 3D Structure    ModBase 3D Structure for Q8WX94
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    0.625ng/ml-20ng/ml
 Sensitivity    0.1ng/ml
 Intra-assay Precision    Intra-assay CV(%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NLRP7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NLRP7 purchase    MBS9337822 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NLR family, pyrin domain containing 7 (NLRP7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625ng/ml-20ng/ml in biological research samples containing NLRP7, with an estimated sensitivity of 0.1ng/ml. The ELISA analytical biochemical technique of the MBS9337822 kit is based on NLRP7 antibody-NLRP7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NLRP7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NLRP7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for NLRP7 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NLRP7 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances
Sample Manual Insert of MBS9337822. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NLRP7. It may not necessarily be applicable to this product.
 NCBI GI #    187937176
 NCBI GeneID    199713
 NCBI Accession #    NP_001120727.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001127255.1 [Other Products]
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 UniProt Primary Accession #    Q8WX94 [Other Products]
 UniProt Secondary Accession #    Q32MH8; Q7RTR1; E9PE16 [Other Products]
 UniProt Related Accession #    Q8WX94 [Other Products]
 Molecular Weight    111,807 Da
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 NCBI Official Full Name    NACHT, LRR and PYD domains-containing protein 7 isoform 3
 NCBI Official Synonym Full Names    NLR family, pyrin domain containing 7
 NCBI Official Symbol    NLRP7 [Similar Products]
 NCBI Official Synonym Symbols   
HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4
[Similar Products]
 NCBI Protein Information    NACHT, LRR and PYD domains-containing protein 7; PYRIN-containing Apaf1-like protein 3; NACHT, LRR and PYD containing protein 7; NACHT, leucine rich repeat and PYD containing 7; nucleotide-binding oligomerization domain protein 12; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7
 UniProt Protein Name    NACHT, LRR and PYD domains-containing protein 7
 UniProt Synonym Protein Names   
Nucleotide-binding oligomerization domain protein 12; PYRIN-containing APAF1-like protein 3
 Protein Family    NACHT, LRR and PYD domains-containing protein
 UniProt Gene Name    NLRP7 [Similar Products]
 UniProt Synonym Gene Names    NALP7; NOD12; PYPAF3 [Similar Products]
 UniProt Entry Name    NALP7_HUMAN
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 NCBI Summary for NLRP7    This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NLRP7    NLRP7: Inhibits CASP1/caspase-1-dependent IL1B secretion. Defects in NLRP7 are the cause of hydatidiform mole recurrent type 1 (HYDM1). A disorder characterized by excessive trophoblast development and the presence of a growing mass of tissue inside the uterus at the beginning of a pregnancy. It leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi. Belongs to the NLRP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 19q13.42

Molecular Function: ATP binding

Disease: Hydatidiform Mole, Recurrent, 1
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 Research Articles on NLRP7    1. The absence of mutations in women with Androgenetic complete hydatidiform moles supports a role for NLRP7 or KHDC3L in Biparental hydatidiform moles only.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with NLRP7 elisa kitOrgans/Tissues associated with NLRP7 elisa kit
 Disease Name  Pubmed Publications
 Hydatidiform Mole Antibodies  >29 publications with NLRP7 and Hydatidiform Mole
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with NLRP7 and Blood
 Placenta Antibodies  >5 publications with NLRP7 and Placenta
 Embryonic Tissue Antibodies  >4 publications with NLRP7 and Embryonic Tissue
 Brain Antibodies  >1 publications with NLRP7 and Brain
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