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NOGO-A elisa kit :: Human NOGO-A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9310926 NOGO-A elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   


 Product Synonym Names    Human NOGO-A ELISA kit; NOGO-A
 Product Gene Name   

NOGO-A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    604475
 3D Structure    ModBase 3D Structure for Q9NQC3
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NOGO-A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NOGO-A purchase    MBS9310926 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NOGO-A, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing NOGO-A, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9310926 kit is based on NOGO-A antibody-NOGO-A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NOGO-A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NOGO-A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for NOGO-A elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NOGO-A (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9310926. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NOGO-A. It may not necessarily be applicable to this product.
 NCBI GI #    76879695
 NCBI GeneID    57142
 NCBI Accession #    BAE45717.1 [Other Products]
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 UniProt Primary Accession #    Q9NQC3 [Other Products]
 UniProt Secondary Accession #    O94962; Q7L7Q5; Q7L7Q6; Q7L7Q8; Q8IUA4; Q96B16; Q9BXG5; Q9H212; Q9H3I3; Q9UQ42; Q9Y293 [Other Products]
 UniProt Related Accession #    Q9NQC3 [Other Products]
 Molecular Weight    108,450 Da
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 NCBI Official Full Name    NOGO-A, partial
 NCBI Official Synonym Full Names    reticulon 4
 NCBI Official Symbol    RTN4 [Similar Products]
 NCBI Official Synonym Symbols   
ASY; NSP; NOGO; NOGOC; RTN-X; NOGO-A; NSP-CL; Nogo-B; Nogo-C; RTN4-A; RTN4-C; RTN4-B1; RTN4-B2; NI220/250; Nbla00271; Nbla10545
[Similar Products]
 NCBI Protein Information    reticulon-4; foocen; Human NogoA; reticulon 5; My043 protein; neurite outgrowth inhibitor; neurite growth inhibitor 220; neuroendocrine-specific protein C homolog
 UniProt Protein Name    Reticulon-4
 UniProt Synonym Protein Names   
Foocen; Neurite outgrowth inhibitor; Nogo protein; Neuroendocrine-specific protein; NSP; Neuroendocrine-specific protein C homolog; RTN-x; Reticulon-5
 UniProt Gene Name    RTN4 [Similar Products]
 UniProt Synonym Gene Names    KIAA0886; NOGO; My043; SP1507; Nogo protein; NSP [Similar Products]
 UniProt Entry Name    RTN4_HUMAN
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 NCBI Summary for NOGO-A    This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NOGO-A    Nogo: Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Inhibitor; Membrane protein, multi-pass; Cell development/differentiation; Motility/polarity/chemotaxis; Endoplasmic reticulum; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p16.3

Cellular Component: cell projection; cell soma; endoplasmic reticulum; plasma membrane; integral to endoplasmic reticulum membrane; nuclear envelope; intracellular

Molecular Function: protein binding

Biological Process: regulation of apoptosis; nerve growth factor receptor signaling pathway; apoptosis; cerebral cortex radial glia guided migration; axonal fasciculation; negative regulation of axonogenesis; negative regulation of cell growth; angiogenesis; negative regulation of axon extension; regulation of axonogenesis; regulation of cell migration
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 Research Articles on NOGO-A    1. knockdown of NgR enhanced invasion and adhesion but increased cell apoptosis in C6 cells, suggesting that Nogo-66/NgR might have complex effects on glioma cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NOGO-A elisa kitDiseases associated with NOGO-A elisa kit
 Products by Pathway  Pathway Diagram
 Axonal Growth Inhibition (RHOA Activation) Pathway antibodies  Axonal Growth Inhibition (RHOA Activation) Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signalling By NGF Pathway antibodies  Signalling By NGF Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
 P75 NTR Receptor-mediated Signalling Pathway antibodies  P75 NTR Receptor-mediated Signalling Pathway Diagram
 P75(NTR)-mediated Signaling Pathway antibodies  P75(NTR)-mediated Signaling Pathway Diagram
 P75NTR Regulates Axonogenesis Pathway antibodies  P75NTR Regulates Axonogenesis Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >11 publications with NOGO-A and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >6 publications with NOGO-A and Cardiovascular Diseases
 Schizophrenia Antibodies  >6 publications with NOGO-A and Schizophrenia
 Disease Models, Animal Antibodies  >4 publications with NOGO-A and Disease Models, Animal
 Heart Diseases Antibodies  >3 publications with NOGO-A and Heart Diseases
 Hypertension Antibodies  >2 publications with NOGO-A and Hypertension
 Atherosclerosis Antibodies  >2 publications with NOGO-A and Atherosclerosis
 Movement Disorders Antibodies  >2 publications with NOGO-A and Movement Disorders
 Carcinoma Antibodies  >2 publications with NOGO-A and Carcinoma
 Liver Diseases Antibodies  >1 publications with NOGO-A and Liver Diseases
Organs/Tissues associated with NOGO-A elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >25 publications with NOGO-A and Brain
 Nerve Antibodies  >23 publications with NOGO-A and Nerve
 Vascular Antibodies  >12 publications with NOGO-A and Vascular
 Muscle Antibodies  >10 publications with NOGO-A and Muscle
 Blood Antibodies  >5 publications with NOGO-A and Blood
 Heart Antibodies  >4 publications with NOGO-A and Heart
 Liver Antibodies  >3 publications with NOGO-A and Liver
 Embryonic Tissue Antibodies  >2 publications with NOGO-A and Embryonic Tissue
 Kidney Antibodies  >2 publications with NOGO-A and Kidney
 Spinal Cord Antibodies  >2 publications with NOGO-A and Spinal Cord
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