AAC24491.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,012 Da
NCBI Official Full Name
natural resistance associated macrophage protein 1
NCBI Official Synonym Symbols
NCBI Protein Information
natural resistance-associated macrophage protein 1; NRAMP 1; solute carrier family 11 member 1
UniProt Protein Name
Natural resistance-associated macrophage protein 1
UniProt Synonym Protein Names
Solute carrier family 11 member 1
UniProt Synonym Gene Names
UniProt Entry Name
NRAM1_PIG
UniProt Comments for SLC11A1
Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe2+ and Mn2+, cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes ().
Research Articles on SLC11A1
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Pathways associated with SLC11A1 elisa kit
Diseases associated with SLC11A1 elisa kit
Organs/Tissues associated with SLC11A1 elisa kit
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