NP_004813.2
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
67,748 Da
NCBI Official Full Name
netrin-1
NCBI Official Synonym Full Names
netrin 1
NCBI Official Synonym Symbols
NCBI Protein Information
netrin-1; netrin 1, mouse, homolog of; epididymis tissue protein Li 131P
UniProt Protein Name
Netrin-1
UniProt Synonym Protein Names
Epididymis tissue protein Li 131P
UniProt Synonym Gene Names
UniProt Entry Name
NET1_HUMAN
NCBI Summary for NTN1
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development. [provided by RefSeq, Jul 2008]
UniProt Comments for NTN1
NTN1: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: cytoplasm; extracellular region; basement membrane
Molecular Function: protein binding
Biological Process: axon guidance; inner ear morphogenesis; cell-cell adhesion; establishment of nucleus localization; apoptosis; positive regulation of axon extension; positive regulation of cell proliferation; neuron migration; negative regulation of axon extension; regulation of cell migration; anterior/posterior axon guidance
Research Articles on NTN1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with NTN1 elisa kit
Pathways associated with NTN1 elisa kit
Diseases associated with NTN1 elisa kit
Organs/Tissues associated with NTN1 elisa kit
|