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NE elisa kit :: Human Norepinephrine (NE) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602530
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $260 +1 FREE 8GB USB
96-Strip-Wells  /  $405 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Norepinephrine (NE), ELISA Kit

★Popular Item★
 Also Known As   

Human Norepinephrine (NE) ELISA Kit

 Product Gene Name   

NE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 604715
 3D Structure    ModBase 3D Structure for P23975
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 Species Reactivity    Human
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 Specificity    No cross-reaction with other factors.
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 Samples    Serum, plasma or cell culture supernatant and organizations in the natural and recombinant NE concentration
 Assay Type    Sandwich
 Detection Range    2000 pg/ml-31.2 pg/ml
 Sensitivity    12 pg/ml.
 Intra-assay Precision    ? 8%
 Inter-assay Precision    ? 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NE purchase    MBS2602530 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Norepinephrine (NE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 2000 pg/ml-31.2 pg/ml in biological research samples containing NE, with an estimated sensitivity of 12 pg/ml. The ELISA analytical biochemical technique of the MBS2602530 kit is based on NE antibody-NE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma or cell culture supernatant and organizations in the natural and recombinant NE concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for NE elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human NE monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of NE elisa kit    NE elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2602530. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NE. It may not necessarily be applicable to this product.
 NCBI GI #    1143479
 NCBI GeneID    6530
 NCBI Accession #    CAA62566.1 [Other Products]
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 UniProt Primary Accession #    P23975 [Other Products]
 UniProt Secondary Accession #    Q96KH8; B2R707; B4DX48 [Other Products]
 UniProt Related Accession #    P23975 [Other Products]
 Molecular Weight    57,370 Da
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 NCBI Official Full Name    norepinephrine transporter
 NCBI Official Synonym Full Names    solute carrier family 6 (neurotransmitter transporter), member 2
 NCBI Official Symbol    SLC6A2 [Similar Products]
 NCBI Official Synonym Symbols   
NET; NAT1; NET1; SLC6A5
[Similar Products]
 NCBI Protein Information    sodium-dependent noradrenaline transporter; norepinephrine transporter; neurotransmitter transporter; solute carrier family 6 member 5; solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
 UniProt Protein Name    Sodium-dependent noradrenaline transporter
 UniProt Synonym Protein Names   
Norepinephrine transporter; NET; Solute carrier family 6 member 2
 UniProt Gene Name    SLC6A2 [Similar Products]
 UniProt Synonym Gene Names    NAT1; NET1; SLC6A5; NET [Similar Products]
 UniProt Entry Name    SC6A2_HUMAN
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 NCBI Summary for NE    This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
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 UniProt Comments for NE    SLC6A2: Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. Defects in SLC6A2 are a cause of orthostatic intolerance (OI). OI is a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 16q12.2

Cellular Component: neuron projection; cell surface; membrane; integral to plasma membrane; plasma membrane; lipid raft

Molecular Function: protein binding; beta-tubulin binding; monoamine transmembrane transporter activity; alpha-tubulin binding; norephinephrine:sodium symporter activity

Biological Process: response to drug; synaptic transmission; norepinephrine transport; transport; neurotransmitter transport; monoamine transport; response to pain; transmembrane transport

Disease: Orthostatic Intolerance
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 Research Articles on NE    1. Duloxetine significantly affected norpepinephrine turnover in the central nervous system and periphery; these effects presumably occurred via inhibition of reuptake by NET, as indicated by effects on functional reuptake inhibition ex vivo.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NE elisa kitPathways associated with NE elisa kit
 Reference Product  PubMed Publications
 SLC18A2 elisa kit  >12 publications with NE and SLC18A2
 PICK1 elisa kit  >2 publications with NE and PICK1
 STX1A elisa kit  >1 publications with NE and STX1A
 Products by Pathway  Pathway Diagram
 Monoamine Transport Pathway antibodies  Monoamine Transport Pathway Diagram
 Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies  Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
Diseases associated with NE elisa kitOrgans/Tissues associated with NE elisa kit
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >120 publications with NE and Mental Disorders
 Nervous System Diseases Antibodies  >49 publications with NE and Nervous System Diseases
 Attention Deficit Disorder with Hyperactivity Antibodies  >49 publications with NE and Attention Deficit Disorder with Hyperactivity
 Cardiovascular Diseases Antibodies  >47 publications with NE and Cardiovascular Diseases
 Depressive Disorder Antibodies  >36 publications with NE and Depressive Disorder
 Heart Diseases Antibodies  >32 publications with NE and Heart Diseases
 Brain Diseases Antibodies  >30 publications with NE and Brain Diseases
 Hypertension Antibodies  >26 publications with NE and Hypertension
 Disease Models, Animal Antibodies  >25 publications with NE and Disease Models, Animal
 Tachycardia Antibodies  >17 publications with NE and Tachycardia
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >276 publications with NE and Brain
 Nerve Antibodies  >267 publications with NE and Nerve
 Muscle Antibodies  >44 publications with NE and Muscle
 Kidney Antibodies  >28 publications with NE and Kidney
 Placenta Antibodies  >18 publications with NE and Placenta
 Intestine Antibodies  >2 publications with NE and Intestine
 Testis Antibodies  >2 publications with NE and Testis
 Prostate Antibodies  >1 publications with NE and Prostate
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